Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green

Research output: Contribution to journalJournal articleResearchpeer-review

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Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green. / Boushel, R; Langberg, Henning; Olesen, J; Nowak, M; Simonsen, L; Bülow, J; Kjaer, M.

In: Journal of Applied Physiology, Vol. 89, No. 5, 11.2000, p. 1868-78.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Boushel, R, Langberg, H, Olesen, J, Nowak, M, Simonsen, L, Bülow, J & Kjaer, M 2000, 'Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green', Journal of Applied Physiology, vol. 89, no. 5, pp. 1868-78.

APA

Boushel, R., Langberg, H., Olesen, J., Nowak, M., Simonsen, L., Bülow, J., & Kjaer, M. (2000). Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green. Journal of Applied Physiology, 89(5), 1868-78.

Vancouver

Boushel R, Langberg H, Olesen J, Nowak M, Simonsen L, Bülow J et al. Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green. Journal of Applied Physiology. 2000 Nov;89(5):1868-78.

Author

Boushel, R ; Langberg, Henning ; Olesen, J ; Nowak, M ; Simonsen, L ; Bülow, J ; Kjaer, M. / Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green. In: Journal of Applied Physiology. 2000 ; Vol. 89, No. 5. pp. 1868-78.

Bibtex

@article{d1de7f84168848d283eb3502cdbae544,
title = "Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green",
abstract = "Using near-infrared spectroscopy (NIRS) and the tracer indocyanine green (ICG), we quantified blood flow in calf muscle and around the Achilles tendon during plantar flexion (1-9 W). For comparison, blood flow in calf muscle was determined by dye dilution in combination with magnetic resonance imaging measures of muscle volume, and, for the peritendon region, blood flow was measured by (133)Xe washout. From rest to a peak load of 9 W, NIRS-ICG blood flow in calf muscle increased from 2.4+/-0.2 to 74+/-5 ml x 100 ml tissue(-1) x min(-1), similar to that measured by reverse dye (77+/-6 ml x 100 ml tissue(-1) x min(-1)). Achilles peritendon blood flow measured by NIRS-ICG rose with exercise from 2.2+/-0.5 to 15.1+/-0.2 ml x 100 ml(-1) x min(-1), which was similar to that determined by (133)Xe washout (2.0+/-0.6 to 14.6+/-0.3 ml x 100 ml tissue(-1) x min(-1)). This is the first study using NIRS and ICG to quantify regional tissue blood flow during exercise in humans. Due to its high spatial and temporal resolution, the technique may be useful for determining regional blood flow distribution and regulation during exercise in humans.",
keywords = "Coloring Agents, Exercise, Humans, Indocyanine Green, Leg, Muscle, Skeletal, Regional Blood Flow, Sensitivity and Specificity, Spectroscopy, Near-Infrared, Xenon Radioisotopes",
author = "R Boushel and Henning Langberg and J Olesen and M Nowak and L Simonsen and J B{\"u}low and M Kjaer",
year = "2000",
month = "11",
language = "English",
volume = "89",
pages = "1868--78",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "5",

}

RIS

TY - JOUR

T1 - Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green

AU - Boushel, R

AU - Langberg, Henning

AU - Olesen, J

AU - Nowak, M

AU - Simonsen, L

AU - Bülow, J

AU - Kjaer, M

PY - 2000/11

Y1 - 2000/11

N2 - Using near-infrared spectroscopy (NIRS) and the tracer indocyanine green (ICG), we quantified blood flow in calf muscle and around the Achilles tendon during plantar flexion (1-9 W). For comparison, blood flow in calf muscle was determined by dye dilution in combination with magnetic resonance imaging measures of muscle volume, and, for the peritendon region, blood flow was measured by (133)Xe washout. From rest to a peak load of 9 W, NIRS-ICG blood flow in calf muscle increased from 2.4+/-0.2 to 74+/-5 ml x 100 ml tissue(-1) x min(-1), similar to that measured by reverse dye (77+/-6 ml x 100 ml tissue(-1) x min(-1)). Achilles peritendon blood flow measured by NIRS-ICG rose with exercise from 2.2+/-0.5 to 15.1+/-0.2 ml x 100 ml(-1) x min(-1), which was similar to that determined by (133)Xe washout (2.0+/-0.6 to 14.6+/-0.3 ml x 100 ml tissue(-1) x min(-1)). This is the first study using NIRS and ICG to quantify regional tissue blood flow during exercise in humans. Due to its high spatial and temporal resolution, the technique may be useful for determining regional blood flow distribution and regulation during exercise in humans.

AB - Using near-infrared spectroscopy (NIRS) and the tracer indocyanine green (ICG), we quantified blood flow in calf muscle and around the Achilles tendon during plantar flexion (1-9 W). For comparison, blood flow in calf muscle was determined by dye dilution in combination with magnetic resonance imaging measures of muscle volume, and, for the peritendon region, blood flow was measured by (133)Xe washout. From rest to a peak load of 9 W, NIRS-ICG blood flow in calf muscle increased from 2.4+/-0.2 to 74+/-5 ml x 100 ml tissue(-1) x min(-1), similar to that measured by reverse dye (77+/-6 ml x 100 ml tissue(-1) x min(-1)). Achilles peritendon blood flow measured by NIRS-ICG rose with exercise from 2.2+/-0.5 to 15.1+/-0.2 ml x 100 ml(-1) x min(-1), which was similar to that determined by (133)Xe washout (2.0+/-0.6 to 14.6+/-0.3 ml x 100 ml tissue(-1) x min(-1)). This is the first study using NIRS and ICG to quantify regional tissue blood flow during exercise in humans. Due to its high spatial and temporal resolution, the technique may be useful for determining regional blood flow distribution and regulation during exercise in humans.

KW - Coloring Agents

KW - Exercise

KW - Humans

KW - Indocyanine Green

KW - Leg

KW - Muscle, Skeletal

KW - Regional Blood Flow

KW - Sensitivity and Specificity

KW - Spectroscopy, Near-Infrared

KW - Xenon Radioisotopes

M3 - Journal article

VL - 89

SP - 1868

EP - 1878

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 5

ER -

ID: 98570611