The effect of running, strength, and vibration strength training on the mechanical, morphological, and biochemical properties of the Achilles tendon in rats

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Kirsten Legerlotz, Peter Schjerling, Henning Langberg, Gert-Peter Brüggemann, Anja Niehoff

Compared with muscle or bone, there is a lack of information about the relationship between tendon adaptation and the applied loading characteristic. The purpose of the present study was to analyze the effect of different exercise modes characterized by very distinct loading patterns on the mechanical, morphological, and biochemical properties of the Achilles tendon. Sixty-four female Sprague-Dawley rats were divided into five groups: nonactive age-matched control (AMC; n = 20), voluntary wheel running (RT; n = 20), vibration strength-trained (LVST; n = 12), high-vibration strength-trained (HVST; n = 6), and high strength-trained (HST; n = 6) group. After a 12-wk-long experimental period, the Achilles tendon was tested mechanically and the cross-sectional area, the soleus and gastrocnemius muscle mass, and mRNA concentration of collagen I, collagen III, tissue inhibitor of metalloproteinase-1 (TIMP-1), transforming growth factor-beta, connective tissue growth factor, and matrix metalloproteinase-2 was determined. Neither in the LVST nor in the HVST group could any adaptation of the Achilles tendon be detected, although the training had an effect on the gastrocnemius muscle mass in the LVST group (P
Original languageEnglish
JournalJournal of Applied Physiology
Volume102
Issue number2
Pages (from-to)564-72
Number of pages9
ISSN8750-7587
DOIs
Publication statusPublished - Feb 2007

    Research areas

  • Achilles Tendon, Adaptation, Physiological, Animals, Biomechanical Phenomena, Collagen, Connective Tissue Growth Factor, Female, Immediate-Early Proteins, Intercellular Signaling Peptides and Proteins, Matrix Metalloproteinase 2, Muscle Strength, Physical Conditioning, Animal, RNA, Messenger, Rats, Rats, Sprague-Dawley, Running, Tissue Inhibitor of Metalloproteinase-1, Transforming Growth Factor beta, Vibration

ID: 98570480