A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group

Research output: Contribution to journalJournal articlepeer-review

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A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group. / Kruse, A Y; Kjaergard, L L; Krogsgaard, K; Gluud, C; Mortensen, E L; Gottschau, A; Bjerg, A M.

In: Controlled Clinical Trials, Vol. 21, No. 3, 06.2000, p. 223-40.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Kruse, AY, Kjaergard, LL, Krogsgaard, K, Gluud, C, Mortensen, EL, Gottschau, A & Bjerg, AM 2000, 'A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group', Controlled Clinical Trials, vol. 21, no. 3, pp. 223-40. https://doi.org/10.1016/s0197-2456(00)00048-9

APA

Kruse, A. Y., Kjaergard, L. L., Krogsgaard, K., Gluud, C., Mortensen, E. L., Gottschau, A., & Bjerg, A. M. (2000). A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group. Controlled Clinical Trials, 21(3), 223-40. https://doi.org/10.1016/s0197-2456(00)00048-9

Vancouver

Kruse AY, Kjaergard LL, Krogsgaard K, Gluud C, Mortensen EL, Gottschau A et al. A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group. Controlled Clinical Trials. 2000 Jun;21(3):223-40. https://doi.org/10.1016/s0197-2456(00)00048-9

Author

Kruse, A Y ; Kjaergard, L L ; Krogsgaard, K ; Gluud, C ; Mortensen, E L ; Gottschau, A ; Bjerg, A M. / A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group. In: Controlled Clinical Trials. 2000 ; Vol. 21, No. 3. pp. 223-40.

Bibtex

@article{f8224aa6056743e09b31c247b79a1ea2,
title = "A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group",
abstract = "To improve the patient education process in clinical research, three information materials describing general aspects of design and conduct of randomized clinical trials were developed. The materials varied in length, reading ability level, and reader appeal. Their influence on knowledge about and attitude toward randomized clinical trials was assessed in a randomized, parallel group, evaluator-blinded trial among 415 outpatients. The patients were randomized to the following groups: control (no intervention), leaflet, brochure, or booklet. Knowledge was assessed by a 17-item multiple-choice questionnaire and attitude was assessed by a 32-item Likert questionnaire at entry and 2 weeks after the intervention. The interventions and the questionnaires were pilot tested and power calculations were performed. At entry, the mean knowledge score was 7.9 points. At follow-up, the knowledge scores increased by 0.5 for the control, 1.0 for the leaflet, 1.6 for the brochure, and 1.4 for the booklet. The brochure and the booklet improved the knowledge score significantly compared with the control. The general attitude was positive at entry (mean 71.5 points). Only the booklet significantly increased the total attitude score (4.8 points) and the randomized clinical trials attitude subscale score (1.8 points). In conclusion, written information significantly improved outpatients' knowledge about and attitude toward randomized clinical trials. Detailed rather than brief information was more effective. Control Clin Trials 2000;21:223-240",
keywords = "Attitude to Health, Humans, Informed Consent, Patient Education as Topic, Pilot Projects, Randomized Controlled Trials as Topic, Single-Blind Method, Surveys and Questionnaires",
author = "Kruse, {A Y} and Kjaergard, {L L} and K Krogsgaard and C Gluud and Mortensen, {E L} and A Gottschau and Bjerg, {A M}",
year = "2000",
month = jun,
doi = "10.1016/s0197-2456(00)00048-9",
language = "English",
volume = "21",
pages = "223--40",
journal = "Controlled Clinical Trials",
issn = "0197-2456",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - A randomized trial assessing the impact of written information on outpatients' knowledge about and attitude toward randomized clinical trials. The INFO trial group

AU - Kruse, A Y

AU - Kjaergard, L L

AU - Krogsgaard, K

AU - Gluud, C

AU - Mortensen, E L

AU - Gottschau, A

AU - Bjerg, A M

PY - 2000/6

Y1 - 2000/6

N2 - To improve the patient education process in clinical research, three information materials describing general aspects of design and conduct of randomized clinical trials were developed. The materials varied in length, reading ability level, and reader appeal. Their influence on knowledge about and attitude toward randomized clinical trials was assessed in a randomized, parallel group, evaluator-blinded trial among 415 outpatients. The patients were randomized to the following groups: control (no intervention), leaflet, brochure, or booklet. Knowledge was assessed by a 17-item multiple-choice questionnaire and attitude was assessed by a 32-item Likert questionnaire at entry and 2 weeks after the intervention. The interventions and the questionnaires were pilot tested and power calculations were performed. At entry, the mean knowledge score was 7.9 points. At follow-up, the knowledge scores increased by 0.5 for the control, 1.0 for the leaflet, 1.6 for the brochure, and 1.4 for the booklet. The brochure and the booklet improved the knowledge score significantly compared with the control. The general attitude was positive at entry (mean 71.5 points). Only the booklet significantly increased the total attitude score (4.8 points) and the randomized clinical trials attitude subscale score (1.8 points). In conclusion, written information significantly improved outpatients' knowledge about and attitude toward randomized clinical trials. Detailed rather than brief information was more effective. Control Clin Trials 2000;21:223-240

AB - To improve the patient education process in clinical research, three information materials describing general aspects of design and conduct of randomized clinical trials were developed. The materials varied in length, reading ability level, and reader appeal. Their influence on knowledge about and attitude toward randomized clinical trials was assessed in a randomized, parallel group, evaluator-blinded trial among 415 outpatients. The patients were randomized to the following groups: control (no intervention), leaflet, brochure, or booklet. Knowledge was assessed by a 17-item multiple-choice questionnaire and attitude was assessed by a 32-item Likert questionnaire at entry and 2 weeks after the intervention. The interventions and the questionnaires were pilot tested and power calculations were performed. At entry, the mean knowledge score was 7.9 points. At follow-up, the knowledge scores increased by 0.5 for the control, 1.0 for the leaflet, 1.6 for the brochure, and 1.4 for the booklet. The brochure and the booklet improved the knowledge score significantly compared with the control. The general attitude was positive at entry (mean 71.5 points). Only the booklet significantly increased the total attitude score (4.8 points) and the randomized clinical trials attitude subscale score (1.8 points). In conclusion, written information significantly improved outpatients' knowledge about and attitude toward randomized clinical trials. Detailed rather than brief information was more effective. Control Clin Trials 2000;21:223-240

KW - Attitude to Health

KW - Humans

KW - Informed Consent

KW - Patient Education as Topic

KW - Pilot Projects

KW - Randomized Controlled Trials as Topic

KW - Single-Blind Method

KW - Surveys and Questionnaires

U2 - 10.1016/s0197-2456(00)00048-9

DO - 10.1016/s0197-2456(00)00048-9

M3 - Journal article

C2 - 10822120

VL - 21

SP - 223

EP - 240

JO - Controlled Clinical Trials

JF - Controlled Clinical Trials

SN - 0197-2456

IS - 3

ER -

ID: 275943674