Analysing the distribution of synaptic vesicles using a spatial point process model

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Standard

Analysing the distribution of synaptic vesicles using a spatial point process model. / Khanmohammadi, Mahdieh; Waagepetersen, Rasmus; Nava, Nicoletta; Nyengaard, Jens; Sporring, Jon.

Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. Association for Computing Machinery, 2014. p. 73-78.

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Harvard

Khanmohammadi, M, Waagepetersen, R, Nava, N, Nyengaard, J & Sporring, J 2014, Analysing the distribution of synaptic vesicles using a spatial point process model. in Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. Association for Computing Machinery, pp. 73-78, 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, Newport Beach, United States, 20/09/2014. https://doi.org/10.1145/2649387.2649404

APA

Khanmohammadi, M., Waagepetersen, R., Nava, N., Nyengaard, J., & Sporring, J. (2014). Analysing the distribution of synaptic vesicles using a spatial point process model. In Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (pp. 73-78). Association for Computing Machinery. https://doi.org/10.1145/2649387.2649404

Vancouver

Khanmohammadi M, Waagepetersen R, Nava N, Nyengaard J, Sporring J. Analysing the distribution of synaptic vesicles using a spatial point process model. In Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. Association for Computing Machinery. 2014. p. 73-78 https://doi.org/10.1145/2649387.2649404

Author

Khanmohammadi, Mahdieh ; Waagepetersen, Rasmus ; Nava, Nicoletta ; Nyengaard, Jens ; Sporring, Jon. / Analysing the distribution of synaptic vesicles using a spatial point process model. Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. Association for Computing Machinery, 2014. pp. 73-78

Bibtex

@inproceedings{94c55600f4de49d5b368d9e6f8de5fdf,
title = "Analysing the distribution of synaptic vesicles using a spatial point process model",
abstract = "Stress can affect the brain functionality in many ways. As the synaptic vesicles have a major role in nervous signal transportation in synapses, their distribution in relationship to the active zone is very important in studying the neuron responses. We study the effect of stress on brain functionality by statistically modelling the distribution of the synaptic vesicles in two groups of rats: a control group subjected to sham stress and a stressed group subjected to a single acute foot-shock (FS)-stress episode.We hypothesize that the synaptic vesicles have different spatial distributions in the two groups. The spatial distributions are modelled using spatial point process models with an inhomogeneous conditional intensity and repulsive pairwise interactions. Our results verify the hypothesis that the two groups have different spatial distributions.",
keywords = "Faculty of Health and Medical Sciences, Synaptic vesicles distribution,, Spatial point process, Serial section transmission electron microscopy images,, Stress",
author = "Mahdieh Khanmohammadi and Rasmus Waagepetersen and Nicoletta Nava and Jens Nyengaard and Jon Sporring",
year = "2014",
doi = "10.1145/2649387.2649404",
language = "English",
pages = "73--78",
booktitle = "Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics",
publisher = "Association for Computing Machinery",
note = "null ; Conference date: 20-09-2014 Through 23-09-2014",

}

RIS

TY - GEN

T1 - Analysing the distribution of synaptic vesicles using a spatial point process model

AU - Khanmohammadi, Mahdieh

AU - Waagepetersen, Rasmus

AU - Nava, Nicoletta

AU - Nyengaard, Jens

AU - Sporring, Jon

N1 - Conference code: 5

PY - 2014

Y1 - 2014

N2 - Stress can affect the brain functionality in many ways. As the synaptic vesicles have a major role in nervous signal transportation in synapses, their distribution in relationship to the active zone is very important in studying the neuron responses. We study the effect of stress on brain functionality by statistically modelling the distribution of the synaptic vesicles in two groups of rats: a control group subjected to sham stress and a stressed group subjected to a single acute foot-shock (FS)-stress episode.We hypothesize that the synaptic vesicles have different spatial distributions in the two groups. The spatial distributions are modelled using spatial point process models with an inhomogeneous conditional intensity and repulsive pairwise interactions. Our results verify the hypothesis that the two groups have different spatial distributions.

AB - Stress can affect the brain functionality in many ways. As the synaptic vesicles have a major role in nervous signal transportation in synapses, their distribution in relationship to the active zone is very important in studying the neuron responses. We study the effect of stress on brain functionality by statistically modelling the distribution of the synaptic vesicles in two groups of rats: a control group subjected to sham stress and a stressed group subjected to a single acute foot-shock (FS)-stress episode.We hypothesize that the synaptic vesicles have different spatial distributions in the two groups. The spatial distributions are modelled using spatial point process models with an inhomogeneous conditional intensity and repulsive pairwise interactions. Our results verify the hypothesis that the two groups have different spatial distributions.

KW - Faculty of Health and Medical Sciences

KW - Synaptic vesicles distribution,

KW - Spatial point process

KW - Serial section transmission electron microscopy images,

KW - Stress

U2 - 10.1145/2649387.2649404

DO - 10.1145/2649387.2649404

M3 - Article in proceedings

SP - 73

EP - 78

BT - Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics

PB - Association for Computing Machinery

Y2 - 20 September 2014 through 23 September 2014

ER -

ID: 159741105