Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015

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Standard

Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015. / Heinrich, Niels Søndergaard; Kriegbaum, Margit; Grand, Mia Klinten; Lind, Bent Struer; Andersen, Christen Lykkegaard; Persson, Frederik.

In: Primary Care Diabetes, Vol. 16, No. 6, 2022, p. 818-823.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Heinrich, NS, Kriegbaum, M, Grand, MK, Lind, BS, Andersen, CL & Persson, F 2022, 'Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015', Primary Care Diabetes, vol. 16, no. 6, pp. 818-823. https://doi.org/10.1016/j.pcd.2022.10.006

APA

Heinrich, N. S., Kriegbaum, M., Grand, M. K., Lind, B. S., Andersen, C. L., & Persson, F. (2022). Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015. Primary Care Diabetes, 16(6), 818-823. https://doi.org/10.1016/j.pcd.2022.10.006

Vancouver

Heinrich NS, Kriegbaum M, Grand MK, Lind BS, Andersen CL, Persson F. Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015. Primary Care Diabetes. 2022;16(6):818-823. https://doi.org/10.1016/j.pcd.2022.10.006

Author

Heinrich, Niels Søndergaard ; Kriegbaum, Margit ; Grand, Mia Klinten ; Lind, Bent Struer ; Andersen, Christen Lykkegaard ; Persson, Frederik. / Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015. In: Primary Care Diabetes. 2022 ; Vol. 16, No. 6. pp. 818-823.

Bibtex

@article{7c8cebd8fe654703821dde8a3b1794f2,
title = "Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015",
abstract = "Aims: Primary care plays an integral role in the management of type 2 diabetes (T2D). We investigated in a large group of individuals in this setting the biochemical profiles, pharmacological management and clinical outcomes as well as their changes over time. Methods: This is a register-based study including relevant laboratory test results requested between 2000 and 2015 by general practitioners in the greater Copenhagen area. We identified 72,044 individuals with T2D on whom data concerning prescription medicine and clinical outcomes were obtained from national registries. Results: The number of individuals with T2D greatly increased from 2001 to 2015. Hemoglobin A1c, estimated glomerular filtration rate and urine albumin creatinine ratio did not change, but cholestrol levels improved. The proportion redeeming anti-diabetics remained around 80%, with an increase for metformin. The use of cardiovascular drugs increased. All-cause and especially cardiovascular mortality decreased over the period. Hospital admissions for non-fatal cardiovascular events dropped. Conclusion: The number of individuals with T2D in primary care increased dramatically whereas pharmacological management, control of risk factors and clinical outcomes seem to have improved. Nevertheless, a conspicuous minority did not receive diabetes-related medication.",
keywords = "Clinical outcomes, Medications, Primary care, Register study, Type 2 diabetes",
author = "Heinrich, {Niels S{\o}ndergaard} and Margit Kriegbaum and Grand, {Mia Klinten} and Lind, {Bent Struer} and Andersen, {Christen Lykkegaard} and Frederik Persson",
note = "Publisher Copyright: {\textcopyright} 2022 Primary Care Diabetes Europe",
year = "2022",
doi = "10.1016/j.pcd.2022.10.006",
language = "English",
volume = "16",
pages = "818--823",
journal = "Primary Care Diabetes",
issn = "1751-9918",
publisher = "Elsevier",
number = "6",

}

RIS

TY - JOUR

T1 - Biochemical profiling, pharmacological management and clinical outcomes in type 2 diabetes in Danish primary care from 2001 to 2015

AU - Heinrich, Niels Søndergaard

AU - Kriegbaum, Margit

AU - Grand, Mia Klinten

AU - Lind, Bent Struer

AU - Andersen, Christen Lykkegaard

AU - Persson, Frederik

N1 - Publisher Copyright: © 2022 Primary Care Diabetes Europe

PY - 2022

Y1 - 2022

N2 - Aims: Primary care plays an integral role in the management of type 2 diabetes (T2D). We investigated in a large group of individuals in this setting the biochemical profiles, pharmacological management and clinical outcomes as well as their changes over time. Methods: This is a register-based study including relevant laboratory test results requested between 2000 and 2015 by general practitioners in the greater Copenhagen area. We identified 72,044 individuals with T2D on whom data concerning prescription medicine and clinical outcomes were obtained from national registries. Results: The number of individuals with T2D greatly increased from 2001 to 2015. Hemoglobin A1c, estimated glomerular filtration rate and urine albumin creatinine ratio did not change, but cholestrol levels improved. The proportion redeeming anti-diabetics remained around 80%, with an increase for metformin. The use of cardiovascular drugs increased. All-cause and especially cardiovascular mortality decreased over the period. Hospital admissions for non-fatal cardiovascular events dropped. Conclusion: The number of individuals with T2D in primary care increased dramatically whereas pharmacological management, control of risk factors and clinical outcomes seem to have improved. Nevertheless, a conspicuous minority did not receive diabetes-related medication.

AB - Aims: Primary care plays an integral role in the management of type 2 diabetes (T2D). We investigated in a large group of individuals in this setting the biochemical profiles, pharmacological management and clinical outcomes as well as their changes over time. Methods: This is a register-based study including relevant laboratory test results requested between 2000 and 2015 by general practitioners in the greater Copenhagen area. We identified 72,044 individuals with T2D on whom data concerning prescription medicine and clinical outcomes were obtained from national registries. Results: The number of individuals with T2D greatly increased from 2001 to 2015. Hemoglobin A1c, estimated glomerular filtration rate and urine albumin creatinine ratio did not change, but cholestrol levels improved. The proportion redeeming anti-diabetics remained around 80%, with an increase for metformin. The use of cardiovascular drugs increased. All-cause and especially cardiovascular mortality decreased over the period. Hospital admissions for non-fatal cardiovascular events dropped. Conclusion: The number of individuals with T2D in primary care increased dramatically whereas pharmacological management, control of risk factors and clinical outcomes seem to have improved. Nevertheless, a conspicuous minority did not receive diabetes-related medication.

KW - Clinical outcomes

KW - Medications

KW - Primary care

KW - Register study

KW - Type 2 diabetes

U2 - 10.1016/j.pcd.2022.10.006

DO - 10.1016/j.pcd.2022.10.006

M3 - Journal article

C2 - 36272916

AN - SCOPUS:85140328995

VL - 16

SP - 818

EP - 823

JO - Primary Care Diabetes

JF - Primary Care Diabetes

SN - 1751-9918

IS - 6

ER -

ID: 332824257