Research areas

  1. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators

    Kaae, B. H., Harpsøe, Kasper, Kvist, T., Mathiesen, Jesper M., Mølck, C., Gloriam, David E., Jimenez, H. N., Uberti, M. A., Nielsen, S. M., Nielsen, Birgitte, Bräuner, Hans, Sauerberg, P., Clausen, Rasmus Prætorius & Madsen, Ulf, 2012, In: ChemMedChem. 7, 3, p. 440-451

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    How to engage experienced medicine users at the counter for a pharmacy-based asthma inhaler service

    Kaae, Susanne & Nørgaard, Lotte Stig, 2012, In: International Journal of Pharmacy Practice. 20, p. 99-106

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

    Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: International Journal of Pharmaceutics. 428, 1-2, p. 171-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction

    Koradia, V. S., Tenho, M., Diego, H. L. D., Ringkjøbing-Elma, M., Møller-Sonnergaard, Jørn, Salonen, J., Lehto, V. & Rantanen, Jukka, 2012, In: Pharmaceutical Research. 29, 1, p. 134-144

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In: Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil

    Kristensen, J. B., Jørgensen, H. & Mu, Huiling, 2012, In: European Journal of Lipid Science and Technology. 114, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors

    Kristensen, L. H., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 168 p.

    Research output: Book/ReportPh.D. thesisResearch

  8. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, P., Kastrup, Jette Sandholm Jensen, Helin, K., Olsen, L. & Gajhede, Michael, Jun 2012, In: F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Internal correction of spectral interferences and mass bias for selenium metabolism studies using enriched stabel isotopes in combination with multiple linear regression

    Lunøe, K., Martinez-Sierra, J. G., Gammelgaard, Bente & Alonso, J. I. G., 2012, In: Analytical and Bioanalytical Chemistry. 402, 9, p. 2749-2763

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Modelling the carbon cycle of Siena province (Tuscany, central Italy)

    Marchi, M., Jørgensen, S. E., Pulselli, F. M., Marchettini, N. & Bastianoni, S., 2012, In: Ecological Modelling. 225, p. 40-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo

    Mullertz, Anette , Fatouros, D. G., Smith, J. R., Vertzoni, M. & Reppas, C., 2012, In: Molecular Pharmaceutics. 9, 2, p. 237-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In: Analytical and Bioanalytical Chemistry. 402, p. 2131-2139

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABAA receptors

    Nilsson, J., Nielsen, E. Ø., Liljefors, T., Nielsen, M. P. C. & Sterner, O., Feb 2012, In: Bioorganic Chemistry. 40, p. 125-130

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Role of Cu2+ in oligomerization and aggregation of alzheimer's amyloid-β peptides

    Pedersen, J. T., 2012, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet. 85 p.

    Research output: Book/ReportPh.D. thesisResearch

  18. Published

    Behaviour of HPMC compacts investigated using UV-imaging

    Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A robust force field based method for calculating conformational energies of charged drug-like molecules

    Pøhlsgaard, J., Harpsøe, Kasper, Jørgensen, Flemming Steen & Olsen, L., 2012, In: Journal of Chemical Information and Modeling. 52, 2, p. 409-419

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation

    Rand, Kasper Dyrberg, Pringle, S. D., Morris, M. & Brown, J. M., 2012, In: Analytical Chemistry. 84, 4, p. 1931-1940

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: Unique role of halogen bonding revealed

    Rohde, L. A. H., Ahring, P. K., Jensen, M. L., Nielsen, E. Ø., Peters, D., Helgstrand, C., Krintel, C., Harpsøe, Kasper, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Balle, T., 3 Feb 2012, In: The Journal of Biological Chemistry. 287, 6, p. 4248-4259

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Comment on "Binding free energies of inhibitors to iron porphyrin complex as a model for cytochrome P450"

    Rydberg, P., Apr 2012, In: Biopolymers. 97, 4, p. 250-251

    Research output: Contribution to journalComment/debateResearchpeer-review

  23. Published

    Ligand-based site of metabolism prediction for cytochrome P450 2D6

    Rydberg, P. & Olsen, L., 12 Jan 2012, In: A C S Medicinal Chemistry Letters. 3, 1, p. 69-73

    Research output: Contribution to journalLetterResearchpeer-review

  24. Published

    Genetic fuzzy system modeling and simulation of vascular behaviour

    Tang, J. & Boonen, H. C. M., 13 Jun 2012. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  25. Published

    In vitro release from oil injectabels for intra-articular administration: importance of interfacial area, diffusivity and partitioning

    Thing, M. A., Larsen, C. S., Østergaard, Jesper, Jensen, H. & Larsen, Susan Weng, 2012, In: European Journal of Pharmaceutical Sciences. 45, 3, p. 351-357

    Research output: Contribution to journalJournal articleResearchpeer-review

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