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Published
Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains
Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 22 Jun 2011, In: B M C Microbiology. 11, 1, p. 144
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice
Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In: Epilepsy Research. 95, 1-2, p. 70-81
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mechanism of Ca²⁺/calmodulin-dependent kinase II regulation of AMPA receptor gating
Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In: Nature Neuroscience. 14, 6, p. 727-735
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy
Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In silico predictions of hERG channel blockers in drug discovery: from ligand-based and target-based approaches to systems chemical biology
Taboureau, O. & Jørgensen, Flemming Steen, Jun 2011, In: Combinatorial Chemistry & High Throughput Screening. 14, 5, p. 375-387
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1
Holm, J., Ferreras, M., Ipsen, H., Würtzen, P. A., Gajhede, Michael, Larsen, J. N., Lund, K. & Spangfort, M. D., 20 May 2011, In: Journal of Biological Chemistry. 286, 20, p. 17569-17578
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Expression and beta-glucan binding properties of Scots pine (Pinus sylvestris L.) antimicrobial protein (Sp-AMP)
Sooriyaarachchi, S., Jaber, E., Covarrubias, A. S., Ubhayasekera, W., Asiegbu, F. O. & Mowbray, S. L., 17 May 2011, In: Plant Molecular Biology. 77, 1-2, p. 33-45
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Extraction and detection of Ionophores in the Aquatic Environment
Bak, S. A., Hansen, M., Krogh, K. A., Björklund, E. & Halling-Sørensen, B., 17 May 2011.
Research output: Contribution to conference › Poster › Research
Published
Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta² -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors
Dallanoce, C., Magrone, P., Matera, C., Frigerio, F., Grazioso, G., De Amici, M., Fucile, S., Piccari, V., Frydenvang, Karla Andrea, Pucci, L., Gotti, C., Clementi, F. & De Micheli, C., 2 May 2011, In: ChemMedChem. 6, 5, p. 889-903
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Thapsigargin affinity purification of intracellular P_2A-type Ca²⁺ATPases
Vandecaetsbeek, I., Christensen, Søren Brøgger, Liu, Huizhen, van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P., 1 May 2011, In: BBA General Subjects. 1813, 5, p. 1118-1127
Research output: Contribution to journal › Journal article › Research › peer-review
Published
1,2,3-triazoles in peptidomimetic chemistry
Pedersen, D. S. & Abell, A., May 2011, In: European Journal of Organic Chemistry. 2011, 13, p. 2399-2411
Research output: Contribution to journal › Review › Research › peer-review
Published
New insights into the GABA_A receptor structure and orthosteric ligand binding: Receptor modeling guided by experimental data
Sander, T., Frølund, Bente, Bruun, A. T., Ivanov, I., McCammon, J. A. & Balle, T., May 2011, In: Proteins: Structure, Function, and Bioinformatics. 79, 5, p. 1458-1477
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Studies of monoamine transporters: Phosphorylation of the serotonin transporter and interactions of antidepressants with the serotonin and norepinephrine transporters
Sørensen, L., May 2011, København: Det Farmaceutiske Fakultet. 174 p.
Research output: Book/Report › Ph.D. thesis › Research
Published
X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase
Yennawar, H., Møller, M., Gillilan, R. & Yennawar, N., May 2011, In: Acta Crystallographica. Section D: Biological Crystallography. 67, Pt 5, p. 440-446
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers
Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In: European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain)
López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y. & Calvo, M. I., 12 Apr 2011, In: Journal of Ethnopharmacology. 134, 3, p. 1014-1017
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Electrophilic organic selenium reagents: protonated seleninic acids as precursors for unsymmetrical aromatic selenides
Stuhr-Hansen, N., Sølling, Theis Ivan & Henriksen, L., 8 Apr 2011, In: Tetrahedron. 67, 14, p. 2633-2643
Research output: Contribution to journal › Journal article › Research › peer-review
Published
ZP2307, a novel cyclic PTH(1-17) analog, reversed established osteopenia in adult ovariectomized rats
Vääräniemi, J., Morko, J., Peng, Z., Rissanen, J. P., Suominen, M. I., Fagerlund, K. M., Suutari, T. A., Boonen, H. C. M., Neerup, T. S., Bak, H. H. & Halleen, J. M., 7 Apr 2011. 1 p.
Research output: Contribution to conference › Poster › Research
Published
Discovery of benzamide analogues as a novel class of 5-HT₃ receptor agonists
Jørgensen, Charlotte Grube, Frølund, Bente, Kehler, J. & Jensen, Anders A., 4 Apr 2011, In: ChemMedChem. 6, 4, p. 725-736
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity
Søvsø Jensen, B., Christensen, Søren Brøgger, Jäger, A. K. & Rønsted, Nina, Apr 2011, In: Biochemical Systematics and Ecology. 39, 2, p. 153-155
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Glutamate receptor agonists: stereochemical aspects
Vogensen, S. B., Greenwood, J. R., Bunch, Lennart & Clausen, Rasmus Prætorius, Apr 2011, In: Current Topics in Medicinal Chemistry. 11, 7, p. 887-906
Research output: Contribution to journal › Review › Research › peer-review
Published
Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction
Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346
Research output: Contribution to journal › Journal article › Research › peer-review
Published
European new safe and innovative medicines initiatives: history and progress (through December 2009)
Bjerrum, Ole Jannik & H. Linden, H., Mar 2011, Translational medicine and drug discovery. Cambridge: Cambridge University Press, p. 265-288 23 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
Published
Metabolic profiling of Rhodiola rosea rhizomes by ¹H NMR spectroscopy
Ioset, K. N., Nyberg, N. T., Van Diermen, D., Malnoe, P., Hostettmann, K., Shikov, A. N. & Jaroszewski, J. W., Mar 2011, In: Phytochemical Analysis. 22, 2, p. 158-165
Research output: Contribution to journal › Journal article › Research › peer-review
Published
G protein- and agonist-bound serotonin 5-HT_2A receptor model activated by steered molecular dynamics simulations
Ísberg, V., Balle, T., Sander, T., Jørgensen, Flemming Steen & Gloriam, David E., 28 Feb 2011, In: Journal of Chemical Information and Modeling. 51, 2, p. 315-325
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp
Runager, K., Basaiawmoit, R. V., Deva, T., Andreasen, M., Valnickova, Z., Sørensen, C. S., Karring, H., Thøgersen, I. B., Christiansen, G., Underhaug, J., Kristensen, T., Nielsen, N. C., Klintworth, G. K., Otzen, D. E. & Enghild, J. J., 18 Feb 2011, In: The Journal of Biological Chemistry. 286, 7, p. 4951-4958
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Medicinal chemistry of competitive kainate receptor antagonists
Larsen, A. M. & Bunch, Lennart, 16 Feb 2011, In: ACS Chemical Neuroscience. 2, 2, p. 60-74
Research output: Contribution to journal › Review › Research › peer-review
Published
Flavonoids and the CNS
Jäger, A. K. & Saaby, Lasse, 10 Feb 2011, In: Molecules. 16, 2, p. 1471-1485
Research output: Contribution to journal › Review › Research › peer-review
Published
Functional and structural studies of neuronal D-serine transporter Asc1
Wang, X., 10 Feb 2011, København: Det Farmaceutiske Fakultet. 148 p.
Research output: Book/Report › Ph.D. thesis › Research
Published
Expedient synthesis of 1,3-substituted benzene peptidomimetics
Bach, Anders & Strømgaard, Kristian, 8 Feb 2011, In: Synthesis. 2011, 5, p. 807-815
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97
Chi, C. N., Bach, Anders, Engström, Å., Strømgaard, Kristian, Lundström, P., Ferguson, N. & Jemth, P., 4 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3597-3606
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors
Pinto, A., Conti, P., Grazioso, G., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte & De Micheli, C., 1 Feb 2011, In: European Journal of Medicinal Chemistry. 46, 2, p. 787-793
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Intestinal drug delivery via hPEPT1 : in vitro and in silico evaluation of the realtionship between substrate, binding and translocation
Omkvist, D. H., Feb 2011, Det Farmaceutiske Fakultet. 51 p.
Research output: Book/Report › Ph.D. thesis › Research
Published
Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.)
Saaby, Lasse, Jäger, A. K., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Feb 2011, In: Phytotherapy Research. 25, 2, p. 195-201
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators
Pøhlsgaard, J., Frydenvang, Karla Andrea, Madsen, Ulf & Kastrup, Jette Sandholm Jensen, 1 Jan 2011, In: Neuropharmacology. 60, 1, p. 135-150
Research output: Contribution to journal › Review › Research › peer-review
Published
Potentiating action of propofol at GABA_A receptors of retinal bipolar cells
Yue, L., Xie, A., Bruzik, K. S., Frølund, Bente, Qian, H. & Pepperberg, D. R., 1 Jan 2011, In: Investigative Ophthalmology & Visual Science. 52, 5, p. 2497-2509
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Purification, crystallization and preliminary X-ray diffraction of the G3BP1 NTF2-like domain
Vognsen, T., Möller, I. R. & Kristensen, O., 1 Jan 2011, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 67, Pt 1, p. 48-50
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors
Nilsson, J., Gidlöf, R., Nielsen, E. Ø., Liljefors, T., Nielsen, M. P. C. & Sterner, O., 1 Jan 2011, In: Bioorganic & Medicinal Chemistry. 19, 1, p. 111-121
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of bile on the oral absorption of poorly water-soluble drugs in rats
Tønsberg, H., Jan 2011, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet. 83 p.
Research output: Book/Report › Ph.D. thesis › Research
Published
On-chip electro membrane extraction with online ultaviolet and mass spectrometric detection
Petersen, Nickolaj J., Foss, S. T., Jensen, H., Hansen, S. H., Skonberg, C., Snakenborg, D., Kutter, J. P. & Pedersen-Bjergaard, Stig, Jan 2011, In: Analytical Chemistry. 83, 1, p. 44-51
Research output: Contribution to journal › Journal article › Research › peer-review
Published
(Eco)teoxicological effects of transformation products: (Not) a research question ?
Hansen, M., 2011.
Research output: Working paper › Research
Published
1H NMR- and HPLC-based metabolomics combined with hyphenated HPLC-SPE-NMR methods for the investigation of herbal remedies and medicinal plants
Agnolet, S., 2011, København: Det Farmaceutiske Fakultet.
Research output: Book/Report › Ph.D. thesis › Research
Published
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin
Jensen, L. B., Petersson, K. & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 68-75
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A ligand's view of target similarity: chemogenomic binding site-directed techniques for drug discovery
Garland, S. L. & Gloriam, David E., 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1872-1881
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A model on the carbon cycling in Lake Taihu, China
Weiping, H., Jørgensen, S. E., Fabing, Z., Yonggen, C., Zhixin, H. & Longyuan, Y., 2011, In: Ecological Modelling. 222, 16, p. 2973-2991
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs
Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Activities of drug transporters and cytochrome P450s in cultures of primary hepatocytes
Jacobsen, J. K., 2011, Det Farmaceutiske Fakultet. 122 p.
Research output: Book/Report › Ph.D. thesis › Research
Published
Adsorption of insulin with varying self-association profiles to a solid Teflon surface-Influence on protein structures, fibrillation tendency and thermal stability
Jørgensen, Lene, Bennedsen, P., Hoffmann, S. V., Pinholt, C., Krogh, R. L., Jensen, M. G., Hostrup, S. & Burkinksky, J. T., 2011, In: European Journal of Pharmaceutical Sciences. 42, 5, p. 509-516
Research output: Contribution to journal › Journal article › Research › peer-review

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