Childhood intelligence in relation to adult coronary heart disease and stroke risk: Evidence from a Danish birth cohort study

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Standard

Childhood intelligence in relation to adult coronary heart disease and stroke risk : Evidence from a Danish birth cohort study. / Batty, G David; Mortensen, Erik L; Nybo Andersen, Anne-Marie; Osler, Merete.

In: Paediatric and Perinatal Epidemiology, Vol. 19, No. 6, 2005, p. 452-459.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Batty, GD, Mortensen, EL, Nybo Andersen, A-M & Osler, M 2005, 'Childhood intelligence in relation to adult coronary heart disease and stroke risk: Evidence from a Danish birth cohort study', Paediatric and Perinatal Epidemiology, vol. 19, no. 6, pp. 452-459. https://doi.org/10.1111/j.1365-3016.2005.00671.x

APA

Batty, G. D., Mortensen, E. L., Nybo Andersen, A-M., & Osler, M. (2005). Childhood intelligence in relation to adult coronary heart disease and stroke risk: Evidence from a Danish birth cohort study. Paediatric and Perinatal Epidemiology, 19(6), 452-459. https://doi.org/10.1111/j.1365-3016.2005.00671.x

Vancouver

Batty GD, Mortensen EL, Nybo Andersen A-M, Osler M. Childhood intelligence in relation to adult coronary heart disease and stroke risk: Evidence from a Danish birth cohort study. Paediatric and Perinatal Epidemiology. 2005;19(6):452-459. https://doi.org/10.1111/j.1365-3016.2005.00671.x

Author

Batty, G David ; Mortensen, Erik L ; Nybo Andersen, Anne-Marie ; Osler, Merete. / Childhood intelligence in relation to adult coronary heart disease and stroke risk : Evidence from a Danish birth cohort study. In: Paediatric and Perinatal Epidemiology. 2005 ; Vol. 19, No. 6. pp. 452-459.

Bibtex

@article{2619ddd09f0011df928f000ea68e967b,
title = "Childhood intelligence in relation to adult coronary heart disease and stroke risk: Evidence from a Danish birth cohort study",
abstract = "While recent studies have reported an inverse relation between childhood intelligence test scores and all-cause mortality in later life, the link with disease-specific outcomes has been rarely examined. Furthermore, the potential confounding effect of birthweight and childhood social circumstances is unknown. We investigated the relation of childhood intelligence with coronary heart disease (CHD) and stroke risk in a cohort of 6910 men born in 1953 in the Copenhagen area of Denmark. Events were ascertained from 1978 to 2000 using a cause-of-death register and hospital discharge records. There were 150 CHD (19 fatal; 131 non-fatal) and 93 stroke (4 fatal; 89 non-fatal) events during follow-up into mid-life. Childhood intelligence was inversely related to CHD with the highest rate apparent in adults with low childhood test scores (HR(lowest vs. highest quartile), 2.70; 95% confidence interval: 1.60, 4.57; P(trend) = 0.0001). After adjustment for paternal social class and birthweight, this association was attenuated only marginally. There was little evidence of a IQ-stroke relationship. The cognitive characteristics captured by IQ testing in the present study, such as communication and problem solving ability, appear to be associated with risk of CHD. Health promotion specialists and clinical practitioners may wish to consider these skills in their interactions with the general public. Replication of these results using studies which hold data on intelligence and socio-economic position across the life course is required.",
author = "Batty, {G David} and Mortensen, {Erik L} and {Nybo Andersen}, Anne-Marie and Merete Osler",
year = "2005",
doi = "10.1111/j.1365-3016.2005.00671.x",
language = "English",
volume = "19",
pages = "452--459",
journal = "Paediatric and Perinatal Epidemiology (Print)",
issn = "0269-5022",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Childhood intelligence in relation to adult coronary heart disease and stroke risk

T2 - Evidence from a Danish birth cohort study

AU - Batty, G David

AU - Mortensen, Erik L

AU - Nybo Andersen, Anne-Marie

AU - Osler, Merete

PY - 2005

Y1 - 2005

N2 - While recent studies have reported an inverse relation between childhood intelligence test scores and all-cause mortality in later life, the link with disease-specific outcomes has been rarely examined. Furthermore, the potential confounding effect of birthweight and childhood social circumstances is unknown. We investigated the relation of childhood intelligence with coronary heart disease (CHD) and stroke risk in a cohort of 6910 men born in 1953 in the Copenhagen area of Denmark. Events were ascertained from 1978 to 2000 using a cause-of-death register and hospital discharge records. There were 150 CHD (19 fatal; 131 non-fatal) and 93 stroke (4 fatal; 89 non-fatal) events during follow-up into mid-life. Childhood intelligence was inversely related to CHD with the highest rate apparent in adults with low childhood test scores (HR(lowest vs. highest quartile), 2.70; 95% confidence interval: 1.60, 4.57; P(trend) = 0.0001). After adjustment for paternal social class and birthweight, this association was attenuated only marginally. There was little evidence of a IQ-stroke relationship. The cognitive characteristics captured by IQ testing in the present study, such as communication and problem solving ability, appear to be associated with risk of CHD. Health promotion specialists and clinical practitioners may wish to consider these skills in their interactions with the general public. Replication of these results using studies which hold data on intelligence and socio-economic position across the life course is required.

AB - While recent studies have reported an inverse relation between childhood intelligence test scores and all-cause mortality in later life, the link with disease-specific outcomes has been rarely examined. Furthermore, the potential confounding effect of birthweight and childhood social circumstances is unknown. We investigated the relation of childhood intelligence with coronary heart disease (CHD) and stroke risk in a cohort of 6910 men born in 1953 in the Copenhagen area of Denmark. Events were ascertained from 1978 to 2000 using a cause-of-death register and hospital discharge records. There were 150 CHD (19 fatal; 131 non-fatal) and 93 stroke (4 fatal; 89 non-fatal) events during follow-up into mid-life. Childhood intelligence was inversely related to CHD with the highest rate apparent in adults with low childhood test scores (HR(lowest vs. highest quartile), 2.70; 95% confidence interval: 1.60, 4.57; P(trend) = 0.0001). After adjustment for paternal social class and birthweight, this association was attenuated only marginally. There was little evidence of a IQ-stroke relationship. The cognitive characteristics captured by IQ testing in the present study, such as communication and problem solving ability, appear to be associated with risk of CHD. Health promotion specialists and clinical practitioners may wish to consider these skills in their interactions with the general public. Replication of these results using studies which hold data on intelligence and socio-economic position across the life course is required.

U2 - 10.1111/j.1365-3016.2005.00671.x

DO - 10.1111/j.1365-3016.2005.00671.x

M3 - Journal article

C2 - 16269073

VL - 19

SP - 452

EP - 459

JO - Paediatric and Perinatal Epidemiology (Print)

JF - Paediatric and Perinatal Epidemiology (Print)

SN - 0269-5022

IS - 6

ER -

ID: 21161788