Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice: study protocol for three cluster-randomised, superiority trials

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice : study protocol for three cluster-randomised, superiority trials. / Curth, Nadja Kehler; Brinck-Claussen, Ursula Ødum; Davidsen, Annette Sofie; Lau, Marianne Engelbrecht; Lundsteen, Merete; Mikkelsen, John Hagel; Csillag, Claudio; Hjorthøj, Carsten; Nordentoft, Merete; Eplov, Lene Falgaard.

In: Trials, Vol. 18, 382 , 16.08.2017, p. 1-13.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Curth, NK, Brinck-Claussen, UØ, Davidsen, AS, Lau, ME, Lundsteen, M, Mikkelsen, JH, Csillag, C, Hjorthøj, C, Nordentoft, M & Eplov, LF 2017, 'Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice: study protocol for three cluster-randomised, superiority trials' Trials, vol. 18, 382 , pp. 1-13. https://doi.org/10.1186/s13063-017-2120-3

APA

Curth, N. K., Brinck-Claussen, U. Ø., Davidsen, A. S., Lau, M. E., Lundsteen, M., Mikkelsen, J. H., ... Eplov, L. F. (2017). Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice: study protocol for three cluster-randomised, superiority trials. Trials, 18, 1-13. [382 ]. https://doi.org/10.1186/s13063-017-2120-3

Vancouver

Curth NK, Brinck-Claussen UØ, Davidsen AS, Lau ME, Lundsteen M, Mikkelsen JH et al. Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice: study protocol for three cluster-randomised, superiority trials. Trials. 2017 Aug 16;18:1-13. 382 . https://doi.org/10.1186/s13063-017-2120-3

Author

Curth, Nadja Kehler ; Brinck-Claussen, Ursula Ødum ; Davidsen, Annette Sofie ; Lau, Marianne Engelbrecht ; Lundsteen, Merete ; Mikkelsen, John Hagel ; Csillag, Claudio ; Hjorthøj, Carsten ; Nordentoft, Merete ; Eplov, Lene Falgaard. / Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice : study protocol for three cluster-randomised, superiority trials. In: Trials. 2017 ; Vol. 18. pp. 1-13.

Bibtex

@article{133db656aba64c7186d9f6140cb733ae,
title = "Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice: study protocol for three cluster-randomised, superiority trials",
abstract = "Background: People with anxiety disorders represent a significant part of a general practitioner’s patient population. However, there are organisational obstacles for optimal treatment, such as a lack of coordination of illness management and limited access to evidence-based treatment such as cognitive behavioral therapy. A limited number of studies suggest that collaborative care has a positive effect on symptoms for people with anxiety disorders. However, most studies are carried out in the USA and none have reported results for social phobia or generalised anxiety disorder separately. Thus, there is a need for studies carried out in different settings for specific anxiety populations.A Danish model for collaborative care (the Collabri model) has been developed for people diagnosed with depression or anxiety disorders. The model is evaluated through four trials, of which three will be outlined in this protocol and focus on panic disorder, generalised anxiety disorder and social phobia. The aim is to investigate whether treatment according to the Collabri model has a better effect than usual treatment on symptoms when provided to people with anxiety disorders.Methods:Three cluster-randomised, clinical superiority trials are set up to investigate treatment according to the Collabri model for collaborative care compared to treatment-as-usual for 364 patients diagnosed with panic disorder, generalised anxiety disorder and social phobia, respectively (total n = 1092). Patients are recruited from general practices located in the Capital Region of Denmark. For all trials, the primary outcome is anxiety symptoms (Beck Anxiety Inventory (BAI)) 6 months after baseline. Secondary outcomes include BAI after 15 months, depression symptoms (Beck Depression Inventory) after 6 months, level of psychosocial functioning (Global Assessment of Functioning) and general psychological symptoms (Symptom Checklist-90-R) after 6 and 15 months.Discussion:Results will add to the limited pool of information about collaborative care for patients with anxiety disorders. To our knowledge, these will be the first carried out in a Danish context and the first to report results for generalised anxiety and social phobia separately. If the trials show positive results, they could contribute to the improvement of future treatment of anxiety disorders.Trial registration:ClinicalTrials.gov, ID: NCT02678624. Retrospectively registered 7 February 2016; last updated 15 August 2016,",
keywords = "Collaborative care, Shared care, Anxiety disorders, Panic disorder, Generalised anxiety disorder, Social phobia, Cluster-randomised trial, General practice",
author = "Curth, {Nadja Kehler} and Brinck-Claussen, {Ursula {\O}dum} and Davidsen, {Annette Sofie} and Lau, {Marianne Engelbrecht} and Merete Lundsteen and Mikkelsen, {John Hagel} and Claudio Csillag and Carsten Hjorth{\o}j and Merete Nordentoft and Eplov, {Lene Falgaard}",
year = "2017",
month = "8",
day = "16",
doi = "10.1186/s13063-017-2120-3",
language = "English",
volume = "18",
pages = "1--13",
journal = "Trials",
issn = "1745-6215",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Collaborative care for panic disorder, generalised anxiety disorder and social phobia in general practice

T2 - study protocol for three cluster-randomised, superiority trials

AU - Curth, Nadja Kehler

AU - Brinck-Claussen, Ursula Ødum

AU - Davidsen, Annette Sofie

AU - Lau, Marianne Engelbrecht

AU - Lundsteen, Merete

AU - Mikkelsen, John Hagel

AU - Csillag, Claudio

AU - Hjorthøj, Carsten

AU - Nordentoft, Merete

AU - Eplov, Lene Falgaard

PY - 2017/8/16

Y1 - 2017/8/16

N2 - Background: People with anxiety disorders represent a significant part of a general practitioner’s patient population. However, there are organisational obstacles for optimal treatment, such as a lack of coordination of illness management and limited access to evidence-based treatment such as cognitive behavioral therapy. A limited number of studies suggest that collaborative care has a positive effect on symptoms for people with anxiety disorders. However, most studies are carried out in the USA and none have reported results for social phobia or generalised anxiety disorder separately. Thus, there is a need for studies carried out in different settings for specific anxiety populations.A Danish model for collaborative care (the Collabri model) has been developed for people diagnosed with depression or anxiety disorders. The model is evaluated through four trials, of which three will be outlined in this protocol and focus on panic disorder, generalised anxiety disorder and social phobia. The aim is to investigate whether treatment according to the Collabri model has a better effect than usual treatment on symptoms when provided to people with anxiety disorders.Methods:Three cluster-randomised, clinical superiority trials are set up to investigate treatment according to the Collabri model for collaborative care compared to treatment-as-usual for 364 patients diagnosed with panic disorder, generalised anxiety disorder and social phobia, respectively (total n = 1092). Patients are recruited from general practices located in the Capital Region of Denmark. For all trials, the primary outcome is anxiety symptoms (Beck Anxiety Inventory (BAI)) 6 months after baseline. Secondary outcomes include BAI after 15 months, depression symptoms (Beck Depression Inventory) after 6 months, level of psychosocial functioning (Global Assessment of Functioning) and general psychological symptoms (Symptom Checklist-90-R) after 6 and 15 months.Discussion:Results will add to the limited pool of information about collaborative care for patients with anxiety disorders. To our knowledge, these will be the first carried out in a Danish context and the first to report results for generalised anxiety and social phobia separately. If the trials show positive results, they could contribute to the improvement of future treatment of anxiety disorders.Trial registration:ClinicalTrials.gov, ID: NCT02678624. Retrospectively registered 7 February 2016; last updated 15 August 2016,

AB - Background: People with anxiety disorders represent a significant part of a general practitioner’s patient population. However, there are organisational obstacles for optimal treatment, such as a lack of coordination of illness management and limited access to evidence-based treatment such as cognitive behavioral therapy. A limited number of studies suggest that collaborative care has a positive effect on symptoms for people with anxiety disorders. However, most studies are carried out in the USA and none have reported results for social phobia or generalised anxiety disorder separately. Thus, there is a need for studies carried out in different settings for specific anxiety populations.A Danish model for collaborative care (the Collabri model) has been developed for people diagnosed with depression or anxiety disorders. The model is evaluated through four trials, of which three will be outlined in this protocol and focus on panic disorder, generalised anxiety disorder and social phobia. The aim is to investigate whether treatment according to the Collabri model has a better effect than usual treatment on symptoms when provided to people with anxiety disorders.Methods:Three cluster-randomised, clinical superiority trials are set up to investigate treatment according to the Collabri model for collaborative care compared to treatment-as-usual for 364 patients diagnosed with panic disorder, generalised anxiety disorder and social phobia, respectively (total n = 1092). Patients are recruited from general practices located in the Capital Region of Denmark. For all trials, the primary outcome is anxiety symptoms (Beck Anxiety Inventory (BAI)) 6 months after baseline. Secondary outcomes include BAI after 15 months, depression symptoms (Beck Depression Inventory) after 6 months, level of psychosocial functioning (Global Assessment of Functioning) and general psychological symptoms (Symptom Checklist-90-R) after 6 and 15 months.Discussion:Results will add to the limited pool of information about collaborative care for patients with anxiety disorders. To our knowledge, these will be the first carried out in a Danish context and the first to report results for generalised anxiety and social phobia separately. If the trials show positive results, they could contribute to the improvement of future treatment of anxiety disorders.Trial registration:ClinicalTrials.gov, ID: NCT02678624. Retrospectively registered 7 February 2016; last updated 15 August 2016,

KW - Collaborative care

KW - Shared care

KW - Anxiety disorders

KW - Panic disorder

KW - Generalised anxiety disorder

KW - Social phobia

KW - Cluster-randomised trial

KW - General practice

U2 - 10.1186/s13063-017-2120-3

DO - 10.1186/s13063-017-2120-3

M3 - Journal article

VL - 18

SP - 1

EP - 13

JO - Trials

JF - Trials

SN - 1745-6215

M1 - 382

ER -

ID: 186781597