Concise synthesis of new bridged-nicotine analogues

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Concise synthesis of new bridged-nicotine analogues. / Crestey, François; Hooyberghs, Geert ; Kristensen, Jesper Langgaard.

In: Tetrahedron, Vol. 68, No. 5, 04.02.2012, p. 1417-1421.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Crestey, F, Hooyberghs, G & Kristensen, JL 2012, 'Concise synthesis of new bridged-nicotine analogues', Tetrahedron, vol. 68, no. 5, pp. 1417-1421. https://doi.org/10.1016/j.tet.2011.12.029

APA

Crestey, F., Hooyberghs, G., & Kristensen, J. L. (2012). Concise synthesis of new bridged-nicotine analogues. Tetrahedron, 68(5), 1417-1421. https://doi.org/10.1016/j.tet.2011.12.029

Vancouver

Crestey F, Hooyberghs G, Kristensen JL. Concise synthesis of new bridged-nicotine analogues. Tetrahedron. 2012 Feb 4;68(5):1417-1421. https://doi.org/10.1016/j.tet.2011.12.029

Author

Crestey, François ; Hooyberghs, Geert ; Kristensen, Jesper Langgaard. / Concise synthesis of new bridged-nicotine analogues. In: Tetrahedron. 2012 ; Vol. 68, No. 5. pp. 1417-1421.

Bibtex

@article{19582b1688104f10b1c3ad948450e287,
title = "Concise synthesis of new bridged-nicotine analogues",
abstract = "This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23{\%} and 40{\%} overall yield, respectively.",
keywords = "Former Faculty of Pharmaceutical Sciences",
author = "Fran{\cc}ois Crestey and Geert Hooyberghs and Kristensen, {Jesper Langgaard}",
note = "Keywords: Pyridine metallation; Bridged-nicotine analogue; Suzukie-Miyaura cross-coupling reaction; Nicotinic acetylcholine receptor; Intramolecular reductive amination",
year = "2012",
month = "2",
day = "4",
doi = "10.1016/j.tet.2011.12.029",
language = "English",
volume = "68",
pages = "1417--1421",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Pergamon Press",
number = "5",

}

RIS

TY - JOUR

T1 - Concise synthesis of new bridged-nicotine analogues

AU - Crestey, François

AU - Hooyberghs, Geert

AU - Kristensen, Jesper Langgaard

N1 - Keywords: Pyridine metallation; Bridged-nicotine analogue; Suzukie-Miyaura cross-coupling reaction; Nicotinic acetylcholine receptor; Intramolecular reductive amination

PY - 2012/2/4

Y1 - 2012/2/4

N2 - This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively.

AB - This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively.

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1016/j.tet.2011.12.029

DO - 10.1016/j.tet.2011.12.029

M3 - Journal article

VL - 68

SP - 1417

EP - 1421

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 5

ER -

ID: 37426122