Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Dietary risk factors for inflammatory bowel diseases in a high-risk population : Results from the Faroese IBD study. / Hammer, T; Lophaven, S Nymand; Nielsen, K Rubek; Petersen, M Skaalum; Munkholm, P; Weihe, P; Burisch, J; Lynge, E.

In: United European Gastroenterology Journal, Vol. 7, No. 7, 2019, p. 924-932.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Hammer, T, Lophaven, SN, Nielsen, KR, Petersen, MS, Munkholm, P, Weihe, P, Burisch, J & Lynge, E 2019, 'Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study', United European Gastroenterology Journal, vol. 7, no. 7, pp. 924-932. https://doi.org/10.1177/2050640619852244

APA

Hammer, T., Lophaven, S. N., Nielsen, K. R., Petersen, M. S., Munkholm, P., Weihe, P., ... Lynge, E. (2019). Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study. United European Gastroenterology Journal, 7(7), 924-932. https://doi.org/10.1177/2050640619852244

Vancouver

Hammer T, Lophaven SN, Nielsen KR, Petersen MS, Munkholm P, Weihe P et al. Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study. United European Gastroenterology Journal. 2019;7(7):924-932. https://doi.org/10.1177/2050640619852244

Author

Hammer, T ; Lophaven, S Nymand ; Nielsen, K Rubek ; Petersen, M Skaalum ; Munkholm, P ; Weihe, P ; Burisch, J ; Lynge, E. / Dietary risk factors for inflammatory bowel diseases in a high-risk population : Results from the Faroese IBD study. In: United European Gastroenterology Journal. 2019 ; Vol. 7, No. 7. pp. 924-932.

Bibtex

@article{fbdd1d4e70a645ec8de575db1286eb2d,
title = "Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study",
abstract = "Background: The Faroe Islands currently have the highest recorded inflammatory bowel disease (IBD) incidence in the world.Objective: This study investigated environmental risk factors for IBD in the Faroese population.Methods: Environmental exposure data including lifestyle risk factors and neurotoxicants collected for over 30 years were retrieved from the Children's Health and the Environment in the Faroes (CHEF) cohorts including mainly mother-child pairs, with exposure data collected from pregnant mothers. For lifestyle risk factors, the incidence of IBD and ulcerative colitis (UC) was calculated as the rate ratio (RR) with 95{\%} confidence intervals (CI) in exposed versus non-exposed persons. For neurotoxicants RR was calculated for persons with high versus low exposure.Results: Six cohorts included 5698 persons with complete follow-up data and at least one exposure, and 37 were diagnosed with IBD. For pilot whale/blubber, the RR was 1.02 (95{\%} CI, 0.48-2.18); RR of 1.01 for fish (95{\%} CI, 0.35-2.91); and of the pollutants studied, a statistical significantly increased risk was found for 1,1,1,-trichloro-2,2-bis-(p-chlorophenyl) ethane (p,p'-DDT); RR 3.04 (95{\%} CI, 1.12-8.30). RRs were 1.96 (95{\%} CI, 1.03-3.73) for smoking and 1.10 (95{\%} CI, 0.55-2.19) for alcohol intake.Conclusion: The high IBD incidence is unlikely to be caused by special dietary habits or by environmental pollutants.",
author = "T Hammer and Lophaven, {S Nymand} and Nielsen, {K Rubek} and Petersen, {M Skaalum} and P Munkholm and P Weihe and J Burisch and E Lynge",
year = "2019",
doi = "10.1177/2050640619852244",
language = "English",
volume = "7",
pages = "924--932",
journal = "United European Gastroenterology Journal",
issn = "2050-6406",
publisher = "SAGE Publications",
number = "7",

}

RIS

TY - JOUR

T1 - Dietary risk factors for inflammatory bowel diseases in a high-risk population

T2 - Results from the Faroese IBD study

AU - Hammer, T

AU - Lophaven, S Nymand

AU - Nielsen, K Rubek

AU - Petersen, M Skaalum

AU - Munkholm, P

AU - Weihe, P

AU - Burisch, J

AU - Lynge, E

PY - 2019

Y1 - 2019

N2 - Background: The Faroe Islands currently have the highest recorded inflammatory bowel disease (IBD) incidence in the world.Objective: This study investigated environmental risk factors for IBD in the Faroese population.Methods: Environmental exposure data including lifestyle risk factors and neurotoxicants collected for over 30 years were retrieved from the Children's Health and the Environment in the Faroes (CHEF) cohorts including mainly mother-child pairs, with exposure data collected from pregnant mothers. For lifestyle risk factors, the incidence of IBD and ulcerative colitis (UC) was calculated as the rate ratio (RR) with 95% confidence intervals (CI) in exposed versus non-exposed persons. For neurotoxicants RR was calculated for persons with high versus low exposure.Results: Six cohorts included 5698 persons with complete follow-up data and at least one exposure, and 37 were diagnosed with IBD. For pilot whale/blubber, the RR was 1.02 (95% CI, 0.48-2.18); RR of 1.01 for fish (95% CI, 0.35-2.91); and of the pollutants studied, a statistical significantly increased risk was found for 1,1,1,-trichloro-2,2-bis-(p-chlorophenyl) ethane (p,p'-DDT); RR 3.04 (95% CI, 1.12-8.30). RRs were 1.96 (95% CI, 1.03-3.73) for smoking and 1.10 (95% CI, 0.55-2.19) for alcohol intake.Conclusion: The high IBD incidence is unlikely to be caused by special dietary habits or by environmental pollutants.

AB - Background: The Faroe Islands currently have the highest recorded inflammatory bowel disease (IBD) incidence in the world.Objective: This study investigated environmental risk factors for IBD in the Faroese population.Methods: Environmental exposure data including lifestyle risk factors and neurotoxicants collected for over 30 years were retrieved from the Children's Health and the Environment in the Faroes (CHEF) cohorts including mainly mother-child pairs, with exposure data collected from pregnant mothers. For lifestyle risk factors, the incidence of IBD and ulcerative colitis (UC) was calculated as the rate ratio (RR) with 95% confidence intervals (CI) in exposed versus non-exposed persons. For neurotoxicants RR was calculated for persons with high versus low exposure.Results: Six cohorts included 5698 persons with complete follow-up data and at least one exposure, and 37 were diagnosed with IBD. For pilot whale/blubber, the RR was 1.02 (95% CI, 0.48-2.18); RR of 1.01 for fish (95% CI, 0.35-2.91); and of the pollutants studied, a statistical significantly increased risk was found for 1,1,1,-trichloro-2,2-bis-(p-chlorophenyl) ethane (p,p'-DDT); RR 3.04 (95% CI, 1.12-8.30). RRs were 1.96 (95% CI, 1.03-3.73) for smoking and 1.10 (95% CI, 0.55-2.19) for alcohol intake.Conclusion: The high IBD incidence is unlikely to be caused by special dietary habits or by environmental pollutants.

U2 - 10.1177/2050640619852244

DO - 10.1177/2050640619852244

M3 - Journal article

C2 - 31428417

VL - 7

SP - 924

EP - 932

JO - United European Gastroenterology Journal

JF - United European Gastroenterology Journal

SN - 2050-6406

IS - 7

ER -

ID: 235859135