Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women

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Standard

Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women. / Østerdal, M L; Strøm, M; Klemmensen, A K; Knudsen, V K; Juhl, M; Halldorsson, T I; Andersen, Anne-Marie Nybo; Magnus, P; Olsen, S F.

In: British Journal of Obstetrics and Gynecology, Vol. 116, No. 1, 2008, p. 98-107.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Østerdal, ML, Strøm, M, Klemmensen, AK, Knudsen, VK, Juhl, M, Halldorsson, TI, Andersen, A-MN, Magnus, P & Olsen, SF 2008, 'Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women', British Journal of Obstetrics and Gynecology, vol. 116, no. 1, pp. 98-107. https://doi.org/10.1111/j.1471-0528.2008.02001.x

APA

Østerdal, M. L., Strøm, M., Klemmensen, A. K., Knudsen, V. K., Juhl, M., Halldorsson, T. I., Andersen, A-M. N., Magnus, P., & Olsen, S. F. (2008). Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women. British Journal of Obstetrics and Gynecology, 116(1), 98-107. https://doi.org/10.1111/j.1471-0528.2008.02001.x

Vancouver

Østerdal ML, Strøm M, Klemmensen AK, Knudsen VK, Juhl M, Halldorsson TI et al. Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women. British Journal of Obstetrics and Gynecology. 2008;116(1):98-107. https://doi.org/10.1111/j.1471-0528.2008.02001.x

Author

Østerdal, M L ; Strøm, M ; Klemmensen, A K ; Knudsen, V K ; Juhl, M ; Halldorsson, T I ; Andersen, Anne-Marie Nybo ; Magnus, P ; Olsen, S F. / Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women. In: British Journal of Obstetrics and Gynecology. 2008 ; Vol. 116, No. 1. pp. 98-107.

Bibtex

@article{b70b53c072ee11df928f000ea68e967b,
title = "Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women",
abstract = "OBJECTIVE: To examine the association between physical activity in early pregnancy and risk of pre-eclampsia. DESIGN: Prospective cohort. SETTING: Denmark. POPULATION: A total of 85,139 pregnant Danish women, recruited between 1996 and 2002. METHODS: The authors assessed leisure time physical activity in first trimester by a telephone interview and categorised women a priori into seven groups: 0 (reference), 1-44, 45-74, 75-149, 150-269, 270-419 and 420+ minutes/week. Pre-eclampsia diagnoses were extracted from the Danish National Patient Registry. A number of potential confounders were adjusted for by logistic regression. MAIN OUTCOME MEASURES: Pre-eclampsia and severe pre-eclampsia. RESULTS: The two highest physical activity levels were associated with increased risk of severe pre-eclampsia compared with the nonexercising group, with adjusted odds ratios of 1.65 (95% CI: 1.11-2.43) and 1.78 (95% CI: 1.07-2.95), whereas more moderate levels of physical activity (1-270 minutes/week) had no statistically significant association with risk of pre-eclampsia (total n = 85,139). CONCLUSIONS: We were unable to document a protective effect of leisure time physical activity against pre-eclampsia. Our data even suggest that leisure time physical activity exceeding 270 minutes/week in first trimester may increase risk of severe pre-eclampsia.",
author = "{\O}sterdal, {M L} and M Str{\o}m and Klemmensen, {A K} and Knudsen, {V K} and M Juhl and Halldorsson, {T I} and Andersen, {Anne-Marie Nybo} and P Magnus and Olsen, {S F}",
note = "Keywords: Adult; Denmark; Epidemiologic Methods; Exercise; Female; Humans; Leisure Activities; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Young Adult",
year = "2008",
doi = "10.1111/j.1471-0528.2008.02001.x",
language = "English",
volume = "116",
pages = "98--107",
journal = "BJOG: An International Journal of Obstetrics and Gynaecology",
issn = "0140-7686",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Does leisure time physical activity in early pregnancy protect against pre-eclampsia? Prospective cohort in Danish women

AU - Østerdal, M L

AU - Strøm, M

AU - Klemmensen, A K

AU - Knudsen, V K

AU - Juhl, M

AU - Halldorsson, T I

AU - Andersen, Anne-Marie Nybo

AU - Magnus, P

AU - Olsen, S F

N1 - Keywords: Adult; Denmark; Epidemiologic Methods; Exercise; Female; Humans; Leisure Activities; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Young Adult

PY - 2008

Y1 - 2008

N2 - OBJECTIVE: To examine the association between physical activity in early pregnancy and risk of pre-eclampsia. DESIGN: Prospective cohort. SETTING: Denmark. POPULATION: A total of 85,139 pregnant Danish women, recruited between 1996 and 2002. METHODS: The authors assessed leisure time physical activity in first trimester by a telephone interview and categorised women a priori into seven groups: 0 (reference), 1-44, 45-74, 75-149, 150-269, 270-419 and 420+ minutes/week. Pre-eclampsia diagnoses were extracted from the Danish National Patient Registry. A number of potential confounders were adjusted for by logistic regression. MAIN OUTCOME MEASURES: Pre-eclampsia and severe pre-eclampsia. RESULTS: The two highest physical activity levels were associated with increased risk of severe pre-eclampsia compared with the nonexercising group, with adjusted odds ratios of 1.65 (95% CI: 1.11-2.43) and 1.78 (95% CI: 1.07-2.95), whereas more moderate levels of physical activity (1-270 minutes/week) had no statistically significant association with risk of pre-eclampsia (total n = 85,139). CONCLUSIONS: We were unable to document a protective effect of leisure time physical activity against pre-eclampsia. Our data even suggest that leisure time physical activity exceeding 270 minutes/week in first trimester may increase risk of severe pre-eclampsia.

AB - OBJECTIVE: To examine the association between physical activity in early pregnancy and risk of pre-eclampsia. DESIGN: Prospective cohort. SETTING: Denmark. POPULATION: A total of 85,139 pregnant Danish women, recruited between 1996 and 2002. METHODS: The authors assessed leisure time physical activity in first trimester by a telephone interview and categorised women a priori into seven groups: 0 (reference), 1-44, 45-74, 75-149, 150-269, 270-419 and 420+ minutes/week. Pre-eclampsia diagnoses were extracted from the Danish National Patient Registry. A number of potential confounders were adjusted for by logistic regression. MAIN OUTCOME MEASURES: Pre-eclampsia and severe pre-eclampsia. RESULTS: The two highest physical activity levels were associated with increased risk of severe pre-eclampsia compared with the nonexercising group, with adjusted odds ratios of 1.65 (95% CI: 1.11-2.43) and 1.78 (95% CI: 1.07-2.95), whereas more moderate levels of physical activity (1-270 minutes/week) had no statistically significant association with risk of pre-eclampsia (total n = 85,139). CONCLUSIONS: We were unable to document a protective effect of leisure time physical activity against pre-eclampsia. Our data even suggest that leisure time physical activity exceeding 270 minutes/week in first trimester may increase risk of severe pre-eclampsia.

U2 - 10.1111/j.1471-0528.2008.02001.x

DO - 10.1111/j.1471-0528.2008.02001.x

M3 - Journal article

C2 - 19055653

VL - 116

SP - 98

EP - 107

JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

SN - 0140-7686

IS - 1

ER -

ID: 20196906