Does shared family background influence the impact of educational differences on early mortality?

Research output: Contribution to journal › Journal article › peer-review

Standard

Does shared family background influence the impact of educational differences on early mortality? / Søndergaard, Grethe; Mortensen, Laust H; Andersen, Anne-Marie Nybo; Andersen, Per Kragh; Dalton, Susanne Oksbjerg; Madsen, Mia Lund; Osler, Merete.

In: American Journal of Epidemiology, Vol. 176, No. 8, 2012, p. 675-83.

Research output: Contribution to journal › Journal article › peer-review

Harvard

Søndergaard, G, Mortensen, LH, Andersen, A-MN, Andersen, PK, Dalton, SO, Madsen, ML & Osler, M 2012, 'Does shared family background influence the impact of educational differences on early mortality?', American Journal of Epidemiology, vol. 176, no. 8, pp. 675-83. https://doi.org/10.1093/aje/kws230

APA

Søndergaard, G., Mortensen, L. H., Andersen, A-M. N., Andersen, P. K., Dalton, S. O., Madsen, M. L., & Osler, M. (2012). Does shared family background influence the impact of educational differences on early mortality? American Journal of Epidemiology, 176(8), 675-83. https://doi.org/10.1093/aje/kws230

Vancouver

Søndergaard G, Mortensen LH, Andersen A-MN, Andersen PK, Dalton SO, Madsen ML et al. Does shared family background influence the impact of educational differences on early mortality? American Journal of Epidemiology. 2012;176(8):675-83. https://doi.org/10.1093/aje/kws230

Author

Søndergaard, Grethe ; Mortensen, Laust H ; Andersen, Anne-Marie Nybo ; Andersen, Per Kragh ; Dalton, Susanne Oksbjerg ; Madsen, Mia Lund ; Osler, Merete. / Does shared family background influence the impact of educational differences on early mortality?. In: American Journal of Epidemiology. 2012 ; Vol. 176, No. 8. pp. 675-83.

Bibtex

@article{90de7104c412478d9cfdb6696c9f04c1,
title = "Does shared family background influence the impact of educational differences on early mortality?",
abstract = "The mechanisms behind social differences in mortality rates have been debated. The authors examined the extent to which shared family background and health in early life could explain the association between educational status and all-cause mortality rates using a sibling design. The study was register-based and included all individuals born in Denmark between 1950 and 1979 who had at least 1 full sibling born in the same time period (n = 1,381,436). All individuals were followed from 28 years of age until death, emigration, or December 2009. The authors used Cox regression analyses to estimate hazard ratios for mortality according to educational level. Conventional cohort and intersibling analyses were carried out and conducted separately for deaths occurring before and after the age of 45 years, respectively. The cohort analyses showed an inverse association between educational status and all-cause mortality that was strongest for males, increased with younger birth cohorts, and tended to be strongest in the analyses of death before 45 years of age. The associations were attenuated slightly in the intersibling analyses and after adjustment for serious health conditions in early life. Hence, health selection and confounding by factors shared by siblings explained only a minor part of the association between educational level and all-cause mortality.",
keywords = "Adult, Algorithms, Cause of Death, Denmark, Educational Status, Family, Female, Follow-Up Studies, Health Status Disparities, Humans, Incidence, Male, Middle Aged, Neoplasms, Odds Ratio, Poverty, Proportional Hazards Models, Risk Factors, Siblings, Survival Rate",
author = "Grethe S{\o}ndergaard and Mortensen, {Laust H} and Andersen, {Anne-Marie Nybo} and Andersen, {Per Kragh} and Dalton, {Susanne Oksbjerg} and Madsen, {Mia Lund} and Merete Osler",
year = "2012",
doi = "10.1093/aje/kws230",
language = "English",
volume = "176",
pages = "675--83",
journal = "American Journal of Epidemiology",
issn = "0002-9262",
publisher = "Oxford University Press",
number = "8",

}

RIS

TY - JOUR

T1 - Does shared family background influence the impact of educational differences on early mortality?

AU - Søndergaard, Grethe

AU - Mortensen, Laust H

AU - Andersen, Anne-Marie Nybo

AU - Andersen, Per Kragh

AU - Dalton, Susanne Oksbjerg

AU - Madsen, Mia Lund

AU - Osler, Merete

PY - 2012

Y1 - 2012

N2 - The mechanisms behind social differences in mortality rates have been debated. The authors examined the extent to which shared family background and health in early life could explain the association between educational status and all-cause mortality rates using a sibling design. The study was register-based and included all individuals born in Denmark between 1950 and 1979 who had at least 1 full sibling born in the same time period (n = 1,381,436). All individuals were followed from 28 years of age until death, emigration, or December 2009. The authors used Cox regression analyses to estimate hazard ratios for mortality according to educational level. Conventional cohort and intersibling analyses were carried out and conducted separately for deaths occurring before and after the age of 45 years, respectively. The cohort analyses showed an inverse association between educational status and all-cause mortality that was strongest for males, increased with younger birth cohorts, and tended to be strongest in the analyses of death before 45 years of age. The associations were attenuated slightly in the intersibling analyses and after adjustment for serious health conditions in early life. Hence, health selection and confounding by factors shared by siblings explained only a minor part of the association between educational level and all-cause mortality.

AB - The mechanisms behind social differences in mortality rates have been debated. The authors examined the extent to which shared family background and health in early life could explain the association between educational status and all-cause mortality rates using a sibling design. The study was register-based and included all individuals born in Denmark between 1950 and 1979 who had at least 1 full sibling born in the same time period (n = 1,381,436). All individuals were followed from 28 years of age until death, emigration, or December 2009. The authors used Cox regression analyses to estimate hazard ratios for mortality according to educational level. Conventional cohort and intersibling analyses were carried out and conducted separately for deaths occurring before and after the age of 45 years, respectively. The cohort analyses showed an inverse association between educational status and all-cause mortality that was strongest for males, increased with younger birth cohorts, and tended to be strongest in the analyses of death before 45 years of age. The associations were attenuated slightly in the intersibling analyses and after adjustment for serious health conditions in early life. Hence, health selection and confounding by factors shared by siblings explained only a minor part of the association between educational level and all-cause mortality.

KW - Adult

KW - Algorithms

KW - Cause of Death

KW - Denmark

KW - Educational Status

KW - Family

KW - Female

KW - Follow-Up Studies

KW - Health Status Disparities

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Neoplasms

KW - Odds Ratio

KW - Poverty

KW - Proportional Hazards Models

KW - Risk Factors

KW - Siblings

KW - Survival Rate

U2 - 10.1093/aje/kws230

DO - 10.1093/aje/kws230

M3 - Journal article

C2 - 23024135

VL - 176

SP - 675

EP - 683

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

SN - 0002-9262

IS - 8

ER -

ID: 44353291