Effect of organized screening on incidence and mortality of cervical cancer in Denmark.
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Effect of organized screening on incidence and mortality of cervical cancer in Denmark. / Lynge, E; Madsen, Mette; Engholm, G.
In: Cancer Research, Vol. 49, No. 8, 1989, p. 2157-60.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Effect of organized screening on incidence and mortality of cervical cancer in Denmark.
AU - Lynge, E
AU - Madsen, Mette
AU - Engholm, G
N1 - Keywords: Adult; Denmark; Female; Humans; Middle Aged; Risk Factors; Uterine Cervical Neoplasms; Vaginal Smears
PY - 1989
Y1 - 1989
N2 - Pap smears were used only on a limited scale in Denmark until the late 1960s. Since then smears have been taken both in organized screening programs and outside the programs by general practitioners, private gynecologists, and hospital wards. The present smear-taking activity is equivalent to an average of one smear every second year per woman. As the responsibility for health care rests with the counties in Denmark, differences are found between the counties both concerning organization of screening programs, and concerning the overall level of the smear-taking activity. An analysis using multiplicative Poisson models on county-based incidence and mortality data for women aged 30-59 years in 1963-1982 showed a statistically significant effect of organized screening in reducing both the incidence (RR = 0.67; 95% CI, 0.61-0.73), and the mortality (RR = 0.68; 95% CI, 0.59-0.78) of cervical cancer from 5 years after introduction of an organized screening program. The level of overall smear-taking activity was found to be of limited importance when organized screening was taken into account.
AB - Pap smears were used only on a limited scale in Denmark until the late 1960s. Since then smears have been taken both in organized screening programs and outside the programs by general practitioners, private gynecologists, and hospital wards. The present smear-taking activity is equivalent to an average of one smear every second year per woman. As the responsibility for health care rests with the counties in Denmark, differences are found between the counties both concerning organization of screening programs, and concerning the overall level of the smear-taking activity. An analysis using multiplicative Poisson models on county-based incidence and mortality data for women aged 30-59 years in 1963-1982 showed a statistically significant effect of organized screening in reducing both the incidence (RR = 0.67; 95% CI, 0.61-0.73), and the mortality (RR = 0.68; 95% CI, 0.59-0.78) of cervical cancer from 5 years after introduction of an organized screening program. The level of overall smear-taking activity was found to be of limited importance when organized screening was taken into account.
M3 - Journal article
C2 - 2702657
VL - 49
SP - 2157
EP - 2160
JO - Cancer Research
JF - Cancer Research
SN - 0008-5472
IS - 8
ER -
ID: 4853401