Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets
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Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets. / Kragstrup, J.; Melsen, F.; Mosekilde, L.
In: Metabolic Bone Disease and Related Research, Vol. 3, No. 3, 1981, p. 181-185.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets
AU - Kragstrup, J.
AU - Melsen, F.
AU - Mosekilde, L.
PY - 1981
Y1 - 1981
N2 - The mean wall thickness of iliac trabecular bone packets was determined in undecalcified iliac crest bone specimens from 14 hypothyroid patients, 14 hyperthyroid patients and 28 age- and sex-matched normal controls. Calcification rate and fractional resorption, formation and labeled surfaces in trabecular bone from the patients were measured by conventional histomorphometric methods after double-labeling with tetracycline. The mean wall thickness was increased in the hypothyroid patients (58,9 μm), while no change was demonstrated in the hyperthyroid group (52,5 μm) as compared to the controls (54,0 μm). Calculated estimates of trabecular bone remodeling at the "Basic Multicellular Unit" level showed longer periods of resorption, formation and total remodeling in the hypothyroid than in the hyperthyroid patients.
AB - The mean wall thickness of iliac trabecular bone packets was determined in undecalcified iliac crest bone specimens from 14 hypothyroid patients, 14 hyperthyroid patients and 28 age- and sex-matched normal controls. Calcification rate and fractional resorption, formation and labeled surfaces in trabecular bone from the patients were measured by conventional histomorphometric methods after double-labeling with tetracycline. The mean wall thickness was increased in the hypothyroid patients (58,9 μm), while no change was demonstrated in the hyperthyroid group (52,5 μm) as compared to the controls (54,0 μm). Calculated estimates of trabecular bone remodeling at the "Basic Multicellular Unit" level showed longer periods of resorption, formation and total remodeling in the hypothyroid than in the hyperthyroid patients.
KW - Hyperthyroidism
KW - Hypothyroidism
KW - Mean Wall Thickness
KW - Trabecular Bone Remodeling
U2 - 10.1016/0221-8747(81)90006-0
DO - 10.1016/0221-8747(81)90006-0
M3 - Journal article
C2 - 7347794
AN - SCOPUS:0019754282
VL - 3
SP - 181
EP - 185
JO - Bone
JF - Bone
SN - 8756-3282
IS - 3
ER -
ID: 324421283