Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets

Research output: Contribution to journalJournal articleResearchpeer-review

The mean wall thickness of iliac trabecular bone packets was determined in undecalcified iliac crest bone specimens from 14 hypothyroid patients, 14 hyperthyroid patients and 28 age- and sex-matched normal controls. Calcification rate and fractional resorption, formation and labeled surfaces in trabecular bone from the patients were measured by conventional histomorphometric methods after double-labeling with tetracycline. The mean wall thickness was increased in the hypothyroid patients (58,9 μm), while no change was demonstrated in the hyperthyroid group (52,5 μm) as compared to the controls (54,0 μm). Calculated estimates of trabecular bone remodeling at the "Basic Multicellular Unit" level showed longer periods of resorption, formation and total remodeling in the hypothyroid than in the hyperthyroid patients.

Original languageEnglish
JournalMetabolic Bone Disease and Related Research
Issue number3
Pages (from-to)181-185
Number of pages5
Publication statusPublished - 1981
Externally publishedYes

    Research areas

  • Hyperthyroidism, Hypothyroidism, Mean Wall Thickness, Trabecular Bone Remodeling

ID: 324421283