Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

Research output: Contribution to journalReview

Standard

Factors Affecting the Absorption of Subcutaneously Administered Insulin : Effect on Variability. / Gradel, Anna Katrina Jógvansdóttir; Porsgaard, Trine; Lykkesfeldt, Jens; Seested, Torben; Gram-Nielsen, Sanne; Kristensen, Niels Rode; Refsgaard, Hanne.

In: Journal of Diabetes Research, Vol. 2018, 1205121, 2018.

Research output: Contribution to journalReview

Harvard

Gradel, AKJ, Porsgaard, T, Lykkesfeldt, J, Seested, T, Gram-Nielsen, S, Kristensen, NR & Refsgaard, H 2018, 'Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability', Journal of Diabetes Research, vol. 2018, 1205121. https://doi.org/10.1155/2018/1205121

APA

Gradel, A. K. J., Porsgaard, T., Lykkesfeldt, J., Seested, T., Gram-Nielsen, S., Kristensen, N. R., & Refsgaard, H. (2018). Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability. Journal of Diabetes Research, 2018, [1205121]. https://doi.org/10.1155/2018/1205121

Vancouver

Gradel AKJ, Porsgaard T, Lykkesfeldt J, Seested T, Gram-Nielsen S, Kristensen NR et al. Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability. Journal of Diabetes Research. 2018;2018. 1205121. https://doi.org/10.1155/2018/1205121

Author

Gradel, Anna Katrina Jógvansdóttir ; Porsgaard, Trine ; Lykkesfeldt, Jens ; Seested, Torben ; Gram-Nielsen, Sanne ; Kristensen, Niels Rode ; Refsgaard, Hanne. / Factors Affecting the Absorption of Subcutaneously Administered Insulin : Effect on Variability. In: Journal of Diabetes Research. 2018 ; Vol. 2018.

Bibtex

@article{96743695f9614d47a129af7b61eb8c0a,
title = "Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability",
abstract = "Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels. Since this variability is largely influenced by the absorption of insulin, a deeper understanding of the factors affecting the absorption of insulin from the subcutaneous tissue is necessary in order to improve glycaemic control and the long-term prognosis in people with diabetes. These factors can be related to either the insulin preparation, the injection site/patient, or the injection technique. This review highlights the factors affecting insulin absorption with special attention on the physiological factors at the injection site. In addition, it also provides a detailed description of the insulin absorption process and the various modifications to this process that have been utilized by the different insulin preparations available.",
keywords = "Faculty of Health and Medical Sciences",
author = "Gradel, {Anna Katrina J{\'o}gvansd{\'o}ttir} and Trine Porsgaard and Jens Lykkesfeldt and Torben Seested and Sanne Gram-Nielsen and Kristensen, {Niels Rode} and Hanne Refsgaard",
year = "2018",
doi = "10.1155/2018/1205121",
language = "English",
volume = "2018",
journal = "Journal of Diabetes Research",
issn = "2314-6745",
publisher = "Hindawi Publishing Corporation",

}

RIS

TY - JOUR

T1 - Factors Affecting the Absorption of Subcutaneously Administered Insulin

T2 - Effect on Variability

AU - Gradel, Anna Katrina Jógvansdóttir

AU - Porsgaard, Trine

AU - Lykkesfeldt, Jens

AU - Seested, Torben

AU - Gram-Nielsen, Sanne

AU - Kristensen, Niels Rode

AU - Refsgaard, Hanne

PY - 2018

Y1 - 2018

N2 - Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels. Since this variability is largely influenced by the absorption of insulin, a deeper understanding of the factors affecting the absorption of insulin from the subcutaneous tissue is necessary in order to improve glycaemic control and the long-term prognosis in people with diabetes. These factors can be related to either the insulin preparation, the injection site/patient, or the injection technique. This review highlights the factors affecting insulin absorption with special attention on the physiological factors at the injection site. In addition, it also provides a detailed description of the insulin absorption process and the various modifications to this process that have been utilized by the different insulin preparations available.

AB - Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels. Since this variability is largely influenced by the absorption of insulin, a deeper understanding of the factors affecting the absorption of insulin from the subcutaneous tissue is necessary in order to improve glycaemic control and the long-term prognosis in people with diabetes. These factors can be related to either the insulin preparation, the injection site/patient, or the injection technique. This review highlights the factors affecting insulin absorption with special attention on the physiological factors at the injection site. In addition, it also provides a detailed description of the insulin absorption process and the various modifications to this process that have been utilized by the different insulin preparations available.

KW - Faculty of Health and Medical Sciences

U2 - 10.1155/2018/1205121

DO - 10.1155/2018/1205121

M3 - Review

C2 - 30116732

VL - 2018

JO - Journal of Diabetes Research

JF - Journal of Diabetes Research

SN - 2314-6745

M1 - 1205121

ER -

ID: 199157280