Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study

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Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway : a registry-based study. / Magnus, Maria C.; Oakley, Laura L.; Hansen, Anne V.; Örtqvist, Anne K.; Petersen, Tanja G.; Mortensen, Laust H.; Bliddal, Mette; Andersen, Anne Marie Nybo; Stephansson, Olof; Håberg, Siri E.

In: Scientific Reports, Vol. 12, No. 1, 20625, 2022.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Magnus, MC, Oakley, LL, Hansen, AV, Örtqvist, AK, Petersen, TG, Mortensen, LH, Bliddal, M, Andersen, AMN, Stephansson, O & Håberg, SE 2022, 'Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study', Scientific Reports, vol. 12, no. 1, 20625. https://doi.org/10.1038/s41598-022-25036-1

APA

Magnus, M. C., Oakley, L. L., Hansen, A. V., Örtqvist, A. K., Petersen, T. G., Mortensen, L. H., Bliddal, M., Andersen, A. M. N., Stephansson, O., & Håberg, S. E. (2022). Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study. Scientific Reports, 12(1), [20625]. https://doi.org/10.1038/s41598-022-25036-1

Vancouver

Magnus MC, Oakley LL, Hansen AV, Örtqvist AK, Petersen TG, Mortensen LH et al. Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study. Scientific Reports. 2022;12(1). 20625. https://doi.org/10.1038/s41598-022-25036-1

Author

Magnus, Maria C. ; Oakley, Laura L. ; Hansen, Anne V. ; Örtqvist, Anne K. ; Petersen, Tanja G. ; Mortensen, Laust H. ; Bliddal, Mette ; Andersen, Anne Marie Nybo ; Stephansson, Olof ; Håberg, Siri E. / Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway : a registry-based study. In: Scientific Reports. 2022 ; Vol. 12, No. 1.

Bibtex

@article{78b42783c7884821b881208df992279e,
title = "Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study",
abstract = "It remains unclear whether the rate of fetal death has changed during the COVID-19 pandemic. We assessed the impact of COVID-19 mitigation measures on fetal death in Sweden (449,347 births), Denmark (290,857 pregnancies) and Norway (261,057 pregnancies) using robust population-based registry data. We used Cox regression to assess the impact of the implementation of pandemic mitigation measures on March 12th, 2020, on miscarriage (fetal loss before gestational week 22) and stillbirth (fetal loss after gestational week 22). A total of 11% of 551,914 pregnancies in Denmark and Norway ended in miscarriage, while the proportion of stillbirths among 937,174 births across the three countries was 0.3%. There was no difference in the risk of fetal death during the year following pandemic mitigation measures. For miscarriage, the combined hazard ratio (HR) for Norway and Denmark was 1.01 (95% CI 0.98, 1.03), and for stillbirth, the combined HR for all three countries was 0.99 (95% CI 0.89, 1.09). We observed a slightly decreased risk of miscarriage during the first 4 months, with an HR of 0.94 (95% CI 0.90, 0.99) after lockdown. In conclusion, the risk of fetal death did not change after the implementation of COVID-19 pandemic mitigation measures in the three Scandinavian countries.",
author = "Magnus, {Maria C.} and Oakley, {Laura L.} and Hansen, {Anne V.} and {\"O}rtqvist, {Anne K.} and Petersen, {Tanja G.} and Mortensen, {Laust H.} and Mette Bliddal and Andersen, {Anne Marie Nybo} and Olof Stephansson and H{\aa}berg, {Siri E.}",
note = "Publisher Copyright: {\textcopyright} 2022, The Author(s).",
year = "2022",
doi = "10.1038/s41598-022-25036-1",
language = "English",
volume = "12",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway

T2 - a registry-based study

AU - Magnus, Maria C.

AU - Oakley, Laura L.

AU - Hansen, Anne V.

AU - Örtqvist, Anne K.

AU - Petersen, Tanja G.

AU - Mortensen, Laust H.

AU - Bliddal, Mette

AU - Andersen, Anne Marie Nybo

AU - Stephansson, Olof

AU - Håberg, Siri E.

N1 - Publisher Copyright: © 2022, The Author(s).

PY - 2022

Y1 - 2022

N2 - It remains unclear whether the rate of fetal death has changed during the COVID-19 pandemic. We assessed the impact of COVID-19 mitigation measures on fetal death in Sweden (449,347 births), Denmark (290,857 pregnancies) and Norway (261,057 pregnancies) using robust population-based registry data. We used Cox regression to assess the impact of the implementation of pandemic mitigation measures on March 12th, 2020, on miscarriage (fetal loss before gestational week 22) and stillbirth (fetal loss after gestational week 22). A total of 11% of 551,914 pregnancies in Denmark and Norway ended in miscarriage, while the proportion of stillbirths among 937,174 births across the three countries was 0.3%. There was no difference in the risk of fetal death during the year following pandemic mitigation measures. For miscarriage, the combined hazard ratio (HR) for Norway and Denmark was 1.01 (95% CI 0.98, 1.03), and for stillbirth, the combined HR for all three countries was 0.99 (95% CI 0.89, 1.09). We observed a slightly decreased risk of miscarriage during the first 4 months, with an HR of 0.94 (95% CI 0.90, 0.99) after lockdown. In conclusion, the risk of fetal death did not change after the implementation of COVID-19 pandemic mitigation measures in the three Scandinavian countries.

AB - It remains unclear whether the rate of fetal death has changed during the COVID-19 pandemic. We assessed the impact of COVID-19 mitigation measures on fetal death in Sweden (449,347 births), Denmark (290,857 pregnancies) and Norway (261,057 pregnancies) using robust population-based registry data. We used Cox regression to assess the impact of the implementation of pandemic mitigation measures on March 12th, 2020, on miscarriage (fetal loss before gestational week 22) and stillbirth (fetal loss after gestational week 22). A total of 11% of 551,914 pregnancies in Denmark and Norway ended in miscarriage, while the proportion of stillbirths among 937,174 births across the three countries was 0.3%. There was no difference in the risk of fetal death during the year following pandemic mitigation measures. For miscarriage, the combined hazard ratio (HR) for Norway and Denmark was 1.01 (95% CI 0.98, 1.03), and for stillbirth, the combined HR for all three countries was 0.99 (95% CI 0.89, 1.09). We observed a slightly decreased risk of miscarriage during the first 4 months, with an HR of 0.94 (95% CI 0.90, 0.99) after lockdown. In conclusion, the risk of fetal death did not change after the implementation of COVID-19 pandemic mitigation measures in the three Scandinavian countries.

U2 - 10.1038/s41598-022-25036-1

DO - 10.1038/s41598-022-25036-1

M3 - Journal article

C2 - 36450919

AN - SCOPUS:85143089396

VL - 12

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 20625

ER -

ID: 338822616