High incidence of dementia in Faroese-born female residents in Denmark
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High incidence of dementia in Faroese-born female residents in Denmark. / Petersen, Maria Skaalum; Lophaven, Søren N.; Weihe, Pál; Lynge, Elsebeth.
In: Alzheimer's and Dementia: Translational Research and Clinical Interventions, Vol. 6, No. 1, e12022, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - High incidence of dementia in Faroese-born female residents in Denmark
AU - Petersen, Maria Skaalum
AU - Lophaven, Søren N.
AU - Weihe, Pál
AU - Lynge, Elsebeth
PY - 2020
Y1 - 2020
N2 - Introduction: To assess whether the incidence of dementia among immigrants in Denmark from the Faroe Islands is similar to that of the inhabitants of their new country. Methods: Data on Faroese-born immigrants in Denmark were retrieved from the Danish Central Population Register. Incident dementia cases were identified from the Danish National Patient Register. Standardized incidence ratios (SIRs) were used to compare the dementia incidence in immigrants with the general Danish population. Results: Female, first-generation Faroese immigrants had double the risk of dementia compared with Danes (SIR 2.1, 95% confidence interval [CI] 1.8-2.5); the excess risk prevailed even beyond 10 years in Denmark, and it affected all sub-types of dementia. In male immigrants, only a modest, statistically non-significant excess risk was seen (SIR 1.2, 95% CI 0.9-1.6). Discussion: The observation of an excess risk of dementia in women only but not in men of Faroese origin living in Denmark underscores the complexity of the etiology of dementia.
AB - Introduction: To assess whether the incidence of dementia among immigrants in Denmark from the Faroe Islands is similar to that of the inhabitants of their new country. Methods: Data on Faroese-born immigrants in Denmark were retrieved from the Danish Central Population Register. Incident dementia cases were identified from the Danish National Patient Register. Standardized incidence ratios (SIRs) were used to compare the dementia incidence in immigrants with the general Danish population. Results: Female, first-generation Faroese immigrants had double the risk of dementia compared with Danes (SIR 2.1, 95% confidence interval [CI] 1.8-2.5); the excess risk prevailed even beyond 10 years in Denmark, and it affected all sub-types of dementia. In male immigrants, only a modest, statistically non-significant excess risk was seen (SIR 1.2, 95% CI 0.9-1.6). Discussion: The observation of an excess risk of dementia in women only but not in men of Faroese origin living in Denmark underscores the complexity of the etiology of dementia.
KW - dementia
KW - Faroe Islands
KW - genetic etiology
KW - immigrants
KW - sex difference
U2 - 10.1002/trc2.12022
DO - 10.1002/trc2.12022
M3 - Journal article
C2 - 32346600
AN - SCOPUS:85095950371
VL - 6
JO - Alzheimer's and Dementia: Translational Research and Clinical Interventions
JF - Alzheimer's and Dementia: Translational Research and Clinical Interventions
SN - 2352-8737
IS - 1
M1 - e12022
ER -
ID: 256161136