High-grade cervical lesions after vaccination against human papillomavirus: A Danish cohort study
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High-grade cervical lesions after vaccination against human papillomavirus : A Danish cohort study. / Thamsborg, Lise Holst; Napolitano, George; Larsen, Lise Grupe; Lynge, Elsebeth.
In: Acta Obstetrica et Gynecologica, Vol. 99, No. 10, 2020, p. 1290-1296.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - High-grade cervical lesions after vaccination against human papillomavirus
T2 - A Danish cohort study
AU - Thamsborg, Lise Holst
AU - Napolitano, George
AU - Larsen, Lise Grupe
AU - Lynge, Elsebeth
PY - 2020
Y1 - 2020
N2 - Introduction It is pertinent to evaluate the impact of vaccination against human papillomavirus (HPV) in real life. The aim of the study was to evaluate the real-life impact of HPV vaccination in the first birth cohort of Danish women offered free HPV vaccination as girls and invited to screening at the age of 23 years. Material and methods Women born in 1993 were offered free HPV vaccination at the age of 15 years but women born in 1983 have never been offered free HPV vaccination. We followed these two birth cohorts for 10 years from the age of 15 to after their first invitation to screening, and compared the risk of high-grade cervical intraepithelial neoplasia (CIN). Data were obtained from Danish national health registers. Results Vaccination coverage was 91% in the 1993 birth cohort and
AB - Introduction It is pertinent to evaluate the impact of vaccination against human papillomavirus (HPV) in real life. The aim of the study was to evaluate the real-life impact of HPV vaccination in the first birth cohort of Danish women offered free HPV vaccination as girls and invited to screening at the age of 23 years. Material and methods Women born in 1993 were offered free HPV vaccination at the age of 15 years but women born in 1983 have never been offered free HPV vaccination. We followed these two birth cohorts for 10 years from the age of 15 to after their first invitation to screening, and compared the risk of high-grade cervical intraepithelial neoplasia (CIN). Data were obtained from Danish national health registers. Results Vaccination coverage was 91% in the 1993 birth cohort and
KW - cervical intraepithelial neoplasia
KW - early detection of cancer
KW - human papillomavirus
KW - prevention and control
KW - vaccination
KW - CYTOLOGY
KW - THINPREP
KW - SUREPATH
KW - IMPACT
KW - YOUNG
KW - AGE
U2 - 10.1111/aogs.13935
DO - 10.1111/aogs.13935
M3 - Journal article
C2 - 32754966
VL - 99
SP - 1290
EP - 1296
JO - Acta Obstetricia et Gynecologica Scandinavica
JF - Acta Obstetricia et Gynecologica Scandinavica
SN - 0001-6349
IS - 10
ER -
ID: 247069739