Is there a correlation between androgens and sexual desire in women?

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Is there a correlation between androgens and sexual desire in women? / Wåhlin-Jacobsen, Sarah; Pedersen, Anette Tønnes; Kristensen, Ellids; Læssøe, Nanna Cassandra; Lundqvist, Marika; Cohen, Arieh S; Hougaard, David M; Giraldi, Annamaria.

In: Journal of Sexual Medicine, Vol. 12, No. 2, 02.2015, p. 358-73.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Wåhlin-Jacobsen, S, Pedersen, AT, Kristensen, E, Læssøe, NC, Lundqvist, M, Cohen, AS, Hougaard, DM & Giraldi, A 2015, 'Is there a correlation between androgens and sexual desire in women?', Journal of Sexual Medicine, vol. 12, no. 2, pp. 358-73. https://doi.org/10.1111/jsm.12774

APA

Wåhlin-Jacobsen, S., Pedersen, A. T., Kristensen, E., Læssøe, N. C., Lundqvist, M., Cohen, A. S., Hougaard, D. M., & Giraldi, A. (2015). Is there a correlation between androgens and sexual desire in women? Journal of Sexual Medicine, 12(2), 358-73. https://doi.org/10.1111/jsm.12774

Vancouver

Wåhlin-Jacobsen S, Pedersen AT, Kristensen E, Læssøe NC, Lundqvist M, Cohen AS et al. Is there a correlation between androgens and sexual desire in women? Journal of Sexual Medicine. 2015 Feb;12(2):358-73. https://doi.org/10.1111/jsm.12774

Author

Wåhlin-Jacobsen, Sarah ; Pedersen, Anette Tønnes ; Kristensen, Ellids ; Læssøe, Nanna Cassandra ; Lundqvist, Marika ; Cohen, Arieh S ; Hougaard, David M ; Giraldi, Annamaria. / Is there a correlation between androgens and sexual desire in women?. In: Journal of Sexual Medicine. 2015 ; Vol. 12, No. 2. pp. 358-73.

Bibtex

@article{0b0606e3963044378751249883354b53,

title = "Is there a correlation between androgens and sexual desire in women?",

abstract = "INTRODUCTION: For women, the correlation between circulating androgens and sexual desire is inconclusive. Substitution with androgens at physiological levels improves sexual function in women who experience decreased sexual desire and androgen deficiency from surgical menopause, pituitary disease, and age-related decline in androgen production in the ovaries. Measuring bioactive testosterone is difficult and new methods have been proposed, including measuring the primary androgen metabolite androsterone glucuronide (ADT-G).AIM: The aim of this study was to investigate a possible correlation between serum levels of androgens and sexual desire in women and whether the level of ADT-G is better correlated than the level of circulating androgens with sexual desire.METHODS: This was a cross-sectional study including 560 healthy women aged 19-65 years divided into three age groups. Correlations were considered to be statistically significant at P<0.05.MAIN OUTCOME MEASURE: Sexual desire was determined as the total score of the sexual desire domain of the Female Sexual Function Index. Total testosterone (TT), calculated free testosterone (FT), androstenedione, dehydroepiandrosterone sulfate (DHEAS), and ADT-G were analyzed using mass spectrometry.RESULTS: Sexual desire correlated overall with FT and androstenedione in the total cohort of women. In a subgroup of women aged 25-44 years with no use of systemic hormonal contraception, sexual desire correlated with TT, FT, androstenedione, and DHEAS. In women aged 45-65 years, androstenedione correlated with sexual desire. No correlations between ADT-G and sexual desire were identified.CONCLUSIONS: In the present study, FT and androstenedione were statistically significantly correlated with sexual desire in the total cohort of women. ADT-G did not correlate more strongly than circulating androgens with sexual desire and is therefore not superior to measuring circulating androgens by mass spectrometry.",

keywords = "Adult, Age Factors, Aged, Androgens, Androstenedione, Androstenols, Androsterone, Cross-Sectional Studies, Dehydroepiandrosterone Sulfate, Female, Humans, Libido, Middle Aged, Molecular Sequence Data, Socioeconomic Factors, Testosterone, Women's Health",

author = "Sarah W{\aa}hlin-Jacobsen and Pedersen, {Anette T{\o}nnes} and Ellids Kristensen and L{\ae}ss{\o}e, {Nanna Cassandra} and Marika Lundqvist and Cohen, {Arieh S} and Hougaard, {David M} and Annamaria Giraldi",

note = "{\textcopyright} 2014 International Society for Sexual Medicine.",

year = "2015",

month = feb,

doi = "10.1111/jsm.12774",

language = "English",

volume = "12",

pages = "358--73",

journal = "Journal of Sexual Medicine",

issn = "1743-6095",

publisher = "Elsevier",

number = "2",