Mental vulnerability--a risk factor for ischemic heart disease
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Mental vulnerability--a risk factor for ischemic heart disease. / Eplov, Lene Falgaard; Jørgensen, Torben; Birket-Smith, Morten; Petersen, Janne; Johansen, Christoffer; Mortensen, Erik Lykke.
In: Journal of Psychosomatic Research, Vol. 60, No. 2, 2006, p. 169-76.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Mental vulnerability--a risk factor for ischemic heart disease
AU - Eplov, Lene Falgaard
AU - Jørgensen, Torben
AU - Birket-Smith, Morten
AU - Petersen, Janne
AU - Johansen, Christoffer
AU - Mortensen, Erik Lykke
N1 - Keywords: Adult; Aged; Cause of Death; Cohort Studies; Comorbidity; Denmark; Female; Follow-Up Studies; Health Surveys; Humans; Male; Middle Aged; Myocardial Ischemia; Personality Inventory; Proportional Hazards Models; Psychophysiologic Disorders; Referral and Consultation; Risk Factors; Vulnerable Populations
PY - 2006
Y1 - 2006
N2 - OBJECTIVE: The purpose of this study is to examine whether mental vulnerability is a risk factor for the development of ischemic heart disease (IHD) after adjustment for well-established risk factors. METHODS: In three prospective cohort studies in Copenhagen County, Denmark, we recorded the level of mental vulnerability and possible risk factors to IHD at baseline. For follow-up, the sample was linked to relevant registries to identify all cases of fatal and nonfatal IHD. The relationship between mental vulnerability and IHD was examined using both Kaplan-Meir and Cox proportional hazard models adjusting for possible confounding factors. RESULTS: Mental vulnerability was significantly associated with the risk for IHD (medium mental vulnerability: hazard ratio 1.41, 95% confidence interval 1.04-1.91; and high mental vulnerability: hazard ratio 2.05; 95% confidence interval 1.46-2.88), after adjusting for confounders. CONCLUSION: Our results imply that mental vulnerability is an independent risk factor for IHD.
AB - OBJECTIVE: The purpose of this study is to examine whether mental vulnerability is a risk factor for the development of ischemic heart disease (IHD) after adjustment for well-established risk factors. METHODS: In three prospective cohort studies in Copenhagen County, Denmark, we recorded the level of mental vulnerability and possible risk factors to IHD at baseline. For follow-up, the sample was linked to relevant registries to identify all cases of fatal and nonfatal IHD. The relationship between mental vulnerability and IHD was examined using both Kaplan-Meir and Cox proportional hazard models adjusting for possible confounding factors. RESULTS: Mental vulnerability was significantly associated with the risk for IHD (medium mental vulnerability: hazard ratio 1.41, 95% confidence interval 1.04-1.91; and high mental vulnerability: hazard ratio 2.05; 95% confidence interval 1.46-2.88), after adjusting for confounders. CONCLUSION: Our results imply that mental vulnerability is an independent risk factor for IHD.
U2 - 10.1016/j.jpsychores.2005.05.013
DO - 10.1016/j.jpsychores.2005.05.013
M3 - Journal article
C2 - 16439270
VL - 60
SP - 169
EP - 176
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
SN - 0022-3999
IS - 2
ER -
ID: 12389046