Non-occupational exposure to paint fumes during pregnancy and fetal growth in a general population
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Non-occupational exposure to paint fumes during pregnancy and fetal growth in a general population. / Sørensen, Mette; Andersen, Anne-Marie N; Raaschou-Nielsen, Ole.
In: Environmental Research, Vol. 110, No. 4, 05.2010, p. 383-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Non-occupational exposure to paint fumes during pregnancy and fetal growth in a general population
AU - Sørensen, Mette
AU - Andersen, Anne-Marie N
AU - Raaschou-Nielsen, Ole
N1 - Copyright 2010 Elsevier Inc. All rights reserved.
PY - 2010/5
Y1 - 2010/5
N2 - Occupational exposure to organic solvents during pregnancy has been associated with reduced fetal growth. Though organic solvents in the form of paint fumes are also found in the home environment, no studies have investigated the effect of such exposure in a general population. We studied associations between residential exposure to paint fumes during pregnancy and fetal growth within the Danish National Birth Cohort which consecutively recruited pregnant women from 1996 to 2002 from all over Denmark. Around the 30th pregnancy week, 19,000 mothers were interviewed about use of paint in their residence during pregnancy. The mothers were also asked about smoking habits and alcohol consumption during pregnancy, pre-pregnancy weight, height, parity and occupation. Information on birth weight and gestational age was obtained from national registers. We found that 45% of the mothers had been exposed to paint fumes in their residence during pregnancy. We found a statistically significant inverse relationship between exposure to paint fumes and the risk of being small for gestational age. There were no statistically significant associations between exposure to paint fumes and birth weight and risk of preterm birth after adjustment for potential confounders. Our results suggest that there are no causal relationship between non-occupational exposure to paint fumes in the residence during pregnancy and fetal growth.
AB - Occupational exposure to organic solvents during pregnancy has been associated with reduced fetal growth. Though organic solvents in the form of paint fumes are also found in the home environment, no studies have investigated the effect of such exposure in a general population. We studied associations between residential exposure to paint fumes during pregnancy and fetal growth within the Danish National Birth Cohort which consecutively recruited pregnant women from 1996 to 2002 from all over Denmark. Around the 30th pregnancy week, 19,000 mothers were interviewed about use of paint in their residence during pregnancy. The mothers were also asked about smoking habits and alcohol consumption during pregnancy, pre-pregnancy weight, height, parity and occupation. Information on birth weight and gestational age was obtained from national registers. We found that 45% of the mothers had been exposed to paint fumes in their residence during pregnancy. We found a statistically significant inverse relationship between exposure to paint fumes and the risk of being small for gestational age. There were no statistically significant associations between exposure to paint fumes and birth weight and risk of preterm birth after adjustment for potential confounders. Our results suggest that there are no causal relationship between non-occupational exposure to paint fumes in the residence during pregnancy and fetal growth.
KW - Adult
KW - Cohort Studies
KW - Denmark
KW - Female
KW - Fetal Development
KW - Humans
KW - Infant, Newborn
KW - Infant, Small for Gestational Age
KW - Inhalation Exposure
KW - Maternal Exposure
KW - Paint
KW - Pregnancy
KW - Premature Birth
KW - Solvents
U2 - 10.1016/j.envres.2010.02.011
DO - 10.1016/j.envres.2010.02.011
M3 - Journal article
C2 - 20219188
VL - 110
SP - 383
EP - 387
JO - Environmental Research
JF - Environmental Research
SN - 0013-9351
IS - 4
ER -
ID: 32321292