One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

Research output: Contribution to journalJournal articlepeer-review

Standard

One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder. / Højgaard, Davíð R.M.A.; Hybel, Katja A.; Ivarsson, Tord; Skarphedinsson, Gudmundur; Becker Nissen, Judith; Weidle, Bernhard; Melin, Karin; Torp, Nor Christian; Valderhaug, Robert; Dahl, Kitty; Mortensen, Erik Lykke; Compton, Scott; Jensen, Sanne; Lenhard, Fabian; Hove Thomsen, Per.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 56, No. 11, 2017, p. 940-947.e1.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Højgaard, DRMA, Hybel, KA, Ivarsson, T, Skarphedinsson, G, Becker Nissen, J, Weidle, B, Melin, K, Torp, NC, Valderhaug, R, Dahl, K, Mortensen, EL, Compton, S, Jensen, S, Lenhard, F & Hove Thomsen, P 2017, 'One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 56, no. 11, pp. 940-947.e1. https://doi.org/10.1016/j.jaac.2017.09.002

APA

Højgaard, D. R. M. A., Hybel, K. A., Ivarsson, T., Skarphedinsson, G., Becker Nissen, J., Weidle, B., Melin, K., Torp, N. C., Valderhaug, R., Dahl, K., Mortensen, E. L., Compton, S., Jensen, S., Lenhard, F., & Hove Thomsen, P. (2017). One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 56(11), 940-947.e1. https://doi.org/10.1016/j.jaac.2017.09.002

Vancouver

Højgaard DRMA, Hybel KA, Ivarsson T, Skarphedinsson G, Becker Nissen J, Weidle B et al. One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 2017;56(11):940-947.e1. https://doi.org/10.1016/j.jaac.2017.09.002

Author

Højgaard, Davíð R.M.A. ; Hybel, Katja A. ; Ivarsson, Tord ; Skarphedinsson, Gudmundur ; Becker Nissen, Judith ; Weidle, Bernhard ; Melin, Karin ; Torp, Nor Christian ; Valderhaug, Robert ; Dahl, Kitty ; Mortensen, Erik Lykke ; Compton, Scott ; Jensen, Sanne ; Lenhard, Fabian ; Hove Thomsen, Per. / One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder. In: Journal of the American Academy of Child and Adolescent Psychiatry. 2017 ; Vol. 56, No. 11. pp. 940-947.e1.

Bibtex

@article{4e2f76c69de749cfa1d27ead8bbb701a,
title = "One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder",
abstract = "Objective: This study describes 1-year treatment outcomes from a large sample of cognitive-behavioral therapy (CBT) responders, investigates age as a possible moderator of these treatment outcomes, and evaluates clinical relapse at the 1-year follow-up. Method: This study is the planned follow-up to the Nordic Long-term OCD [obsessive-compulsive disorder] Treatment Study (NordLOTS), which included 177 children and adolescents who were rated as treatment responders following CBT for OCD. Participants were assessed with the Children's Yale−Brown Obsessive-Compulsive Scale (CY-BOCS) at 6- and 12-month follow-up. Treatment response and remission were defined as CY-BOCS total scores ≤15 and ≤10, respectively. Linear mixed-effects models were used to analyze all outcomes. Results: At 1 year, a total of 155 children and adolescents (87.6%) were available for follow-up assessment, with 142 of these (91.6%) rated below a total score of ≤15 on the CY-BOCS. At 1-year follow-up, 121 (78.1%) were in remission. On average, CY-BOCS total scores dropped by 1.72 points during the first year after terminating treatment (p =.001). A total of 28 participants (15.8%) relapsed (CY-BOCS ≥ 16) at either the 6- or 12-month assessment; only 2 patients required additional CBT. Conclusion: Results suggest that manualized CBT in a community setting for pediatric OCD has durable effects for those who respond to an initial course of treatment; children and adolescents who respond to such treatment can be expected to maintain their treatment gains for at least 1 year following acute care. Clinical trial registration information: Nordic Long-term Obsessive-Compulsive Disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.",
keywords = "cognitive-behavioral therapy, follow-up, obsessive-compulsive disorder, pediatric, treatment",
author = "H{\o}jgaard, {Dav{\'i}{\dh} R.M.A.} and Hybel, {Katja A.} and Tord Ivarsson and Gudmundur Skarphedinsson and {Becker Nissen}, Judith and Bernhard Weidle and Karin Melin and Torp, {Nor Christian} and Robert Valderhaug and Kitty Dahl and Mortensen, {Erik Lykke} and Scott Compton and Sanne Jensen and Fabian Lenhard and {Hove Thomsen}, Per",
year = "2017",
doi = "10.1016/j.jaac.2017.09.002",
language = "English",
volume = "56",
pages = "940--947.e1",
journal = "American Academy of Child and Adolescent Psychiatry. Journal",
issn = "0890-8567",
publisher = "Elsevier",
number = "11",

}

RIS

TY - JOUR

T1 - One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

AU - Højgaard, Davíð R.M.A.

AU - Hybel, Katja A.

AU - Ivarsson, Tord

AU - Skarphedinsson, Gudmundur

AU - Becker Nissen, Judith

AU - Weidle, Bernhard

AU - Melin, Karin

AU - Torp, Nor Christian

AU - Valderhaug, Robert

AU - Dahl, Kitty

AU - Mortensen, Erik Lykke

AU - Compton, Scott

AU - Jensen, Sanne

AU - Lenhard, Fabian

AU - Hove Thomsen, Per

PY - 2017

Y1 - 2017

N2 - Objective: This study describes 1-year treatment outcomes from a large sample of cognitive-behavioral therapy (CBT) responders, investigates age as a possible moderator of these treatment outcomes, and evaluates clinical relapse at the 1-year follow-up. Method: This study is the planned follow-up to the Nordic Long-term OCD [obsessive-compulsive disorder] Treatment Study (NordLOTS), which included 177 children and adolescents who were rated as treatment responders following CBT for OCD. Participants were assessed with the Children's Yale−Brown Obsessive-Compulsive Scale (CY-BOCS) at 6- and 12-month follow-up. Treatment response and remission were defined as CY-BOCS total scores ≤15 and ≤10, respectively. Linear mixed-effects models were used to analyze all outcomes. Results: At 1 year, a total of 155 children and adolescents (87.6%) were available for follow-up assessment, with 142 of these (91.6%) rated below a total score of ≤15 on the CY-BOCS. At 1-year follow-up, 121 (78.1%) were in remission. On average, CY-BOCS total scores dropped by 1.72 points during the first year after terminating treatment (p =.001). A total of 28 participants (15.8%) relapsed (CY-BOCS ≥ 16) at either the 6- or 12-month assessment; only 2 patients required additional CBT. Conclusion: Results suggest that manualized CBT in a community setting for pediatric OCD has durable effects for those who respond to an initial course of treatment; children and adolescents who respond to such treatment can be expected to maintain their treatment gains for at least 1 year following acute care. Clinical trial registration information: Nordic Long-term Obsessive-Compulsive Disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.

AB - Objective: This study describes 1-year treatment outcomes from a large sample of cognitive-behavioral therapy (CBT) responders, investigates age as a possible moderator of these treatment outcomes, and evaluates clinical relapse at the 1-year follow-up. Method: This study is the planned follow-up to the Nordic Long-term OCD [obsessive-compulsive disorder] Treatment Study (NordLOTS), which included 177 children and adolescents who were rated as treatment responders following CBT for OCD. Participants were assessed with the Children's Yale−Brown Obsessive-Compulsive Scale (CY-BOCS) at 6- and 12-month follow-up. Treatment response and remission were defined as CY-BOCS total scores ≤15 and ≤10, respectively. Linear mixed-effects models were used to analyze all outcomes. Results: At 1 year, a total of 155 children and adolescents (87.6%) were available for follow-up assessment, with 142 of these (91.6%) rated below a total score of ≤15 on the CY-BOCS. At 1-year follow-up, 121 (78.1%) were in remission. On average, CY-BOCS total scores dropped by 1.72 points during the first year after terminating treatment (p =.001). A total of 28 participants (15.8%) relapsed (CY-BOCS ≥ 16) at either the 6- or 12-month assessment; only 2 patients required additional CBT. Conclusion: Results suggest that manualized CBT in a community setting for pediatric OCD has durable effects for those who respond to an initial course of treatment; children and adolescents who respond to such treatment can be expected to maintain their treatment gains for at least 1 year following acute care. Clinical trial registration information: Nordic Long-term Obsessive-Compulsive Disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.

KW - cognitive-behavioral therapy

KW - follow-up

KW - obsessive-compulsive disorder

KW - pediatric

KW - treatment

U2 - 10.1016/j.jaac.2017.09.002

DO - 10.1016/j.jaac.2017.09.002

M3 - Journal article

C2 - 29096776

AN - SCOPUS:85032443084

VL - 56

SP - 940-947.e1

JO - American Academy of Child and Adolescent Psychiatry. Journal

JF - American Academy of Child and Adolescent Psychiatry. Journal

SN - 0890-8567

IS - 11

ER -

ID: 196915669