Overbelastningsskader i senevaev: indsigt i adaptationsmekanismer

Research output: Contribution to journalJournal articlepeer-review

Standard

Overbelastningsskader i senevaev : indsigt i adaptationsmekanismer. / Kjaer, Michael; Langberg, Henning; Magnusson, Peter.

In: Ugeskrift for Laeger, Vol. 165, No. 14, 2003, p. 1438-43.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Kjaer, M, Langberg, H & Magnusson, P 2003, 'Overbelastningsskader i senevaev: indsigt i adaptationsmekanismer', Ugeskrift for Laeger, vol. 165, no. 14, pp. 1438-43.

APA

Kjaer, M., Langberg, H., & Magnusson, P. (2003). Overbelastningsskader i senevaev: indsigt i adaptationsmekanismer. Ugeskrift for Laeger, 165(14), 1438-43.

Vancouver

Kjaer M, Langberg H, Magnusson P. Overbelastningsskader i senevaev: indsigt i adaptationsmekanismer. Ugeskrift for Laeger. 2003;165(14):1438-43.

Author

Kjaer, Michael ; Langberg, Henning ; Magnusson, Peter. / Overbelastningsskader i senevaev : indsigt i adaptationsmekanismer. In: Ugeskrift for Laeger. 2003 ; Vol. 165, No. 14. pp. 1438-43.

Bibtex

@article{e9e6d7c113484b818340a25e0b4b6e86,
title = "Overbelastningsskader i senevaev: indsigt i adaptationsmekanismer",
abstract = "Tendon tissue plays a central role in force transmission from skeletal muscles to bones and is subject to a considerable amount of overuse injuries associated with occupation and leisure exercise. It has been shown that connective tissue within and around tendon displays increased blood flow and metabolic activity during exercise in vivo and that the extracellular matrix is stimulated by physical activity whereby both collagen synthesis and degradation are enhanced in both tendon and muscle. Training leads to a net synthesis of collagen type I in tendon, and the thicker tendons that well-trained individuals possess contribute to a lower relative loading of the tendons during exercise. Signals for increased collagen synthesis seem to run in parallel with mechanically induced activation of protease driven degradation of connective tissue in tendon and muscle. Hormonal growth factors as well as inflammatory mediators play a role for this effect, but the relative importance of individual factors in the development of acute or chronic tendon injuries in relation to sports remains uncertain. Newly developed in-vivo techniques open new possibilities for a deeper understanding of the pathogenesis behind tendon overuse injuries.",
keywords = "Adaptation, Physiological, Athletic Injuries, Collagen, Cumulative Trauma Disorders, Exercise, Growth Substances, Humans, Occupational Diseases, Tendon Injuries",
author = "Michael Kjaer and Henning Langberg and Peter Magnusson",
year = "2003",
language = "Dansk",
volume = "165",
pages = "1438--43",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "14",

}

RIS

TY - JOUR

T1 - Overbelastningsskader i senevaev

T2 - indsigt i adaptationsmekanismer

AU - Kjaer, Michael

AU - Langberg, Henning

AU - Magnusson, Peter

PY - 2003

Y1 - 2003

N2 - Tendon tissue plays a central role in force transmission from skeletal muscles to bones and is subject to a considerable amount of overuse injuries associated with occupation and leisure exercise. It has been shown that connective tissue within and around tendon displays increased blood flow and metabolic activity during exercise in vivo and that the extracellular matrix is stimulated by physical activity whereby both collagen synthesis and degradation are enhanced in both tendon and muscle. Training leads to a net synthesis of collagen type I in tendon, and the thicker tendons that well-trained individuals possess contribute to a lower relative loading of the tendons during exercise. Signals for increased collagen synthesis seem to run in parallel with mechanically induced activation of protease driven degradation of connective tissue in tendon and muscle. Hormonal growth factors as well as inflammatory mediators play a role for this effect, but the relative importance of individual factors in the development of acute or chronic tendon injuries in relation to sports remains uncertain. Newly developed in-vivo techniques open new possibilities for a deeper understanding of the pathogenesis behind tendon overuse injuries.

AB - Tendon tissue plays a central role in force transmission from skeletal muscles to bones and is subject to a considerable amount of overuse injuries associated with occupation and leisure exercise. It has been shown that connective tissue within and around tendon displays increased blood flow and metabolic activity during exercise in vivo and that the extracellular matrix is stimulated by physical activity whereby both collagen synthesis and degradation are enhanced in both tendon and muscle. Training leads to a net synthesis of collagen type I in tendon, and the thicker tendons that well-trained individuals possess contribute to a lower relative loading of the tendons during exercise. Signals for increased collagen synthesis seem to run in parallel with mechanically induced activation of protease driven degradation of connective tissue in tendon and muscle. Hormonal growth factors as well as inflammatory mediators play a role for this effect, but the relative importance of individual factors in the development of acute or chronic tendon injuries in relation to sports remains uncertain. Newly developed in-vivo techniques open new possibilities for a deeper understanding of the pathogenesis behind tendon overuse injuries.

KW - Adaptation, Physiological

KW - Athletic Injuries

KW - Collagen

KW - Cumulative Trauma Disorders

KW - Exercise

KW - Growth Substances

KW - Humans

KW - Occupational Diseases

KW - Tendon Injuries

M3 - Tidsskriftartikel

C2 - 12715672

VL - 165

SP - 1438

EP - 1443

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 14

ER -

ID: 38367435