Physical and emotional well-being of survivors of childhood and young adult allo-SCT: A Danish national cohort study

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Physical and emotional well-being of survivors of childhood and young adult allo-SCT : A Danish national cohort study. / Jensen, Josef Nathan; Gøtzsche, Frederik; Heilmann, Carsten; Sengeløv, Henrik; Adamsen, Lis; Christensen, Karl Bang; Larsen, Hanne Bækgaard.

In: Pediatric Transplantation, Vol. 20, No. 5, 08.2016, p. 697-706.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Jensen, JN, Gøtzsche, F, Heilmann, C, Sengeløv, H, Adamsen, L, Christensen, KB & Larsen, HB 2016, 'Physical and emotional well-being of survivors of childhood and young adult allo-SCT: A Danish national cohort study', Pediatric Transplantation, vol. 20, no. 5, pp. 697-706. https://doi.org/10.1111/petr.12713

APA

Jensen, J. N., Gøtzsche, F., Heilmann, C., Sengeløv, H., Adamsen, L., Christensen, K. B., & Larsen, H. B. (2016). Physical and emotional well-being of survivors of childhood and young adult allo-SCT: A Danish national cohort study. Pediatric Transplantation, 20(5), 697-706. https://doi.org/10.1111/petr.12713

Vancouver

Jensen JN, Gøtzsche F, Heilmann C, Sengeløv H, Adamsen L, Christensen KB et al. Physical and emotional well-being of survivors of childhood and young adult allo-SCT: A Danish national cohort study. Pediatric Transplantation. 2016 Aug;20(5):697-706. https://doi.org/10.1111/petr.12713

Author

Jensen, Josef Nathan ; Gøtzsche, Frederik ; Heilmann, Carsten ; Sengeløv, Henrik ; Adamsen, Lis ; Christensen, Karl Bang ; Larsen, Hanne Bækgaard. / Physical and emotional well-being of survivors of childhood and young adult allo-SCT : A Danish national cohort study. In: Pediatric Transplantation. 2016 ; Vol. 20, No. 5. pp. 697-706.

Bibtex

@article{3136b7293ac0438eb0b86551b7e49b6b,
title = "Physical and emotional well-being of survivors of childhood and young adult allo-SCT: A Danish national cohort study",
abstract = "The aim of this investigation was to examine, within a population-based study of a national cohort comprising Danish survivors of allo-SCT (n = 148), the long-term effects of allo-SCT in children and young adults. Physical and emotional well-being was assessed using the Short Form 36 (SF-36) and the HADS. Allo-SCT-related data were obtained from the participants' medical records. The study includes 148 patients, with an 89{\%} response rate (n = 132). For comparison purposes, norm data from Danish (1994, n = 6000), Swedish (2006, n = 285), and British (2001, n = 1792) population samples were used. Factors negatively influencing the SF-36 subscales included female gender; TBI; stem cells derived from PB; older age at time of questioning; and living alone. Factors significantly (p < 0.05) influencing HADS were transplantation with stem cells derived from PB and being underweight at time of questioning (median values were within normal range). Overall scores of allo-SCT patients were similar to norm data. In conclusion, this national cohort study shows that patients treated with SCT in early life (<25) and whose survival period extended beyond 10 yr (mean) from SCT, showed similar levels of anxiety, depression, and physical and emotional well-being to those of the normal population.",
keywords = "Journal Article",
author = "Jensen, {Josef Nathan} and Frederik G{\o}tzsche and Carsten Heilmann and Henrik Sengel{\o}v and Lis Adamsen and Christensen, {Karl Bang} and Larsen, {Hanne B{\ae}kgaard}",
note = "{\circledC} 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2016",
month = "8",
doi = "10.1111/petr.12713",
language = "English",
volume = "20",
pages = "697--706",
journal = "Pediatric Transplantation",
issn = "1397-3142",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Physical and emotional well-being of survivors of childhood and young adult allo-SCT

T2 - A Danish national cohort study

AU - Jensen, Josef Nathan

AU - Gøtzsche, Frederik

AU - Heilmann, Carsten

AU - Sengeløv, Henrik

AU - Adamsen, Lis

AU - Christensen, Karl Bang

AU - Larsen, Hanne Bækgaard

N1 - © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2016/8

Y1 - 2016/8

N2 - The aim of this investigation was to examine, within a population-based study of a national cohort comprising Danish survivors of allo-SCT (n = 148), the long-term effects of allo-SCT in children and young adults. Physical and emotional well-being was assessed using the Short Form 36 (SF-36) and the HADS. Allo-SCT-related data were obtained from the participants' medical records. The study includes 148 patients, with an 89% response rate (n = 132). For comparison purposes, norm data from Danish (1994, n = 6000), Swedish (2006, n = 285), and British (2001, n = 1792) population samples were used. Factors negatively influencing the SF-36 subscales included female gender; TBI; stem cells derived from PB; older age at time of questioning; and living alone. Factors significantly (p < 0.05) influencing HADS were transplantation with stem cells derived from PB and being underweight at time of questioning (median values were within normal range). Overall scores of allo-SCT patients were similar to norm data. In conclusion, this national cohort study shows that patients treated with SCT in early life (<25) and whose survival period extended beyond 10 yr (mean) from SCT, showed similar levels of anxiety, depression, and physical and emotional well-being to those of the normal population.

AB - The aim of this investigation was to examine, within a population-based study of a national cohort comprising Danish survivors of allo-SCT (n = 148), the long-term effects of allo-SCT in children and young adults. Physical and emotional well-being was assessed using the Short Form 36 (SF-36) and the HADS. Allo-SCT-related data were obtained from the participants' medical records. The study includes 148 patients, with an 89% response rate (n = 132). For comparison purposes, norm data from Danish (1994, n = 6000), Swedish (2006, n = 285), and British (2001, n = 1792) population samples were used. Factors negatively influencing the SF-36 subscales included female gender; TBI; stem cells derived from PB; older age at time of questioning; and living alone. Factors significantly (p < 0.05) influencing HADS were transplantation with stem cells derived from PB and being underweight at time of questioning (median values were within normal range). Overall scores of allo-SCT patients were similar to norm data. In conclusion, this national cohort study shows that patients treated with SCT in early life (<25) and whose survival period extended beyond 10 yr (mean) from SCT, showed similar levels of anxiety, depression, and physical and emotional well-being to those of the normal population.

KW - Journal Article

U2 - 10.1111/petr.12713

DO - 10.1111/petr.12713

M3 - Journal article

C2 - 27231147

VL - 20

SP - 697

EP - 706

JO - Pediatric Transplantation

JF - Pediatric Transplantation

SN - 1397-3142

IS - 5

ER -

ID: 166376687