Polypharmacy and the risk of drug-drug interactions among Danish elderly: A prescription database study

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Polypharmacy and the risk of drug-drug interactions among Danish elderly : A prescription database study. / Rosholm, J U; Bjerrum, L; Hallas, J; Worm, J; Gram, L F.

In: Danish Medical Bulletin, Vol. 45, No. 2, 1998, p. 210-213.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Rosholm, JU, Bjerrum, L, Hallas, J, Worm, J & Gram, LF 1998, 'Polypharmacy and the risk of drug-drug interactions among Danish elderly: A prescription database study', Danish Medical Bulletin, vol. 45, no. 2, pp. 210-213.

APA

Rosholm, J. U., Bjerrum, L., Hallas, J., Worm, J., & Gram, L. F. (1998). Polypharmacy and the risk of drug-drug interactions among Danish elderly: A prescription database study. Danish Medical Bulletin, 45(2), 210-213.

Vancouver

Rosholm JU, Bjerrum L, Hallas J, Worm J, Gram LF. Polypharmacy and the risk of drug-drug interactions among Danish elderly: A prescription database study. Danish Medical Bulletin. 1998;45(2):210-213.

Author

Rosholm, J U ; Bjerrum, L ; Hallas, J ; Worm, J ; Gram, L F. / Polypharmacy and the risk of drug-drug interactions among Danish elderly : A prescription database study. In: Danish Medical Bulletin. 1998 ; Vol. 45, No. 2. pp. 210-213.

Bibtex

@article{7eb4ada031c611df8ed1000ea68e967b,
title = "Polypharmacy and the risk of drug-drug interactions among Danish elderly: A prescription database study",
abstract = "OBJECTIVE: To analyze the use of all subsidized prescription drugs with special attention to the elderly (> or = 70 years of age), including their use of drug combination generally accepted as carrying a risk of severe interactions. DESIGN: Descriptive prevalence study. SETTING: Odense Pharmacoepidemiological Database, Denmark. The fourth quarter of 1994. SUBJECTS: All inhabitants in the county of Funen, Denmark. MAIN OUTCOME MEASURES: Prevalence of drug use for persons < 70 and > or = 70 years of age including number of drugs used and of drug combinations. Occurrence of 45 drug combinations generally accepted as carrying a risk of severe interactions. RESULTS: Among persons less than 70 years, 67.9% used none, 16.5% used one drug and 15.6% used two or more prescription drugs. The corresponding prevalences for the elderly were 35.7%, 15.9% and 48.4%. The 26,337 elderly patients with at least two drugs used 21,293 different combinations. Of the elderly patients who had purchased > or = two drugs, 4.4% had combinations of drugs carrying a risk of severe interactions. CONCLUSIONS: Most elderly use drugs and usually several drugs concomitantly. The elderly form a heterogeneous group of drug users. Drug combinations carrying a risk of severe interactions are relatively frequent.",
author = "Rosholm, {J U} and L Bjerrum and J Hallas and J Worm and Gram, {L F}",
year = "1998",
language = "English",
volume = "45",
pages = "210--213",
journal = "Danish Medical Journal",
issn = "1603-9629",
publisher = "Almindelige Danske Laegeforening",
number = "2",

}

RIS

TY - JOUR

T1 - Polypharmacy and the risk of drug-drug interactions among Danish elderly

T2 - A prescription database study

AU - Rosholm, J U

AU - Bjerrum, L

AU - Hallas, J

AU - Worm, J

AU - Gram, L F

PY - 1998

Y1 - 1998

N2 - OBJECTIVE: To analyze the use of all subsidized prescription drugs with special attention to the elderly (> or = 70 years of age), including their use of drug combination generally accepted as carrying a risk of severe interactions. DESIGN: Descriptive prevalence study. SETTING: Odense Pharmacoepidemiological Database, Denmark. The fourth quarter of 1994. SUBJECTS: All inhabitants in the county of Funen, Denmark. MAIN OUTCOME MEASURES: Prevalence of drug use for persons < 70 and > or = 70 years of age including number of drugs used and of drug combinations. Occurrence of 45 drug combinations generally accepted as carrying a risk of severe interactions. RESULTS: Among persons less than 70 years, 67.9% used none, 16.5% used one drug and 15.6% used two or more prescription drugs. The corresponding prevalences for the elderly were 35.7%, 15.9% and 48.4%. The 26,337 elderly patients with at least two drugs used 21,293 different combinations. Of the elderly patients who had purchased > or = two drugs, 4.4% had combinations of drugs carrying a risk of severe interactions. CONCLUSIONS: Most elderly use drugs and usually several drugs concomitantly. The elderly form a heterogeneous group of drug users. Drug combinations carrying a risk of severe interactions are relatively frequent.

AB - OBJECTIVE: To analyze the use of all subsidized prescription drugs with special attention to the elderly (> or = 70 years of age), including their use of drug combination generally accepted as carrying a risk of severe interactions. DESIGN: Descriptive prevalence study. SETTING: Odense Pharmacoepidemiological Database, Denmark. The fourth quarter of 1994. SUBJECTS: All inhabitants in the county of Funen, Denmark. MAIN OUTCOME MEASURES: Prevalence of drug use for persons < 70 and > or = 70 years of age including number of drugs used and of drug combinations. Occurrence of 45 drug combinations generally accepted as carrying a risk of severe interactions. RESULTS: Among persons less than 70 years, 67.9% used none, 16.5% used one drug and 15.6% used two or more prescription drugs. The corresponding prevalences for the elderly were 35.7%, 15.9% and 48.4%. The 26,337 elderly patients with at least two drugs used 21,293 different combinations. Of the elderly patients who had purchased > or = two drugs, 4.4% had combinations of drugs carrying a risk of severe interactions. CONCLUSIONS: Most elderly use drugs and usually several drugs concomitantly. The elderly form a heterogeneous group of drug users. Drug combinations carrying a risk of severe interactions are relatively frequent.

M3 - Journal article

C2 - 9587704

VL - 45

SP - 210

EP - 213

JO - Danish Medical Journal

JF - Danish Medical Journal

SN - 1603-9629

IS - 2

ER -

ID: 18686189