Quality assessment of Tulbaghia rhizomes

Research output: Contribution to journal › Journal article › peer-review

Standard

Quality assessment of Tulbaghia rhizomes. / Jäger, Anna; Stafford, Gary Ivan.

In: South African Journal of Botany, Vol. 82, 09.2012, p. 92-98.

Research output: Contribution to journal › Journal article › peer-review

Harvard

Jäger, A & Stafford, GI 2012, 'Quality assessment of Tulbaghia rhizomes', South African Journal of Botany, vol. 82, pp. 92-98. https://doi.org/10.1016/j.sajb.2012.07.025

APA

Jäger, A., & Stafford, G. I. (2012). Quality assessment of Tulbaghia rhizomes. South African Journal of Botany, 82, 92-98. https://doi.org/10.1016/j.sajb.2012.07.025

Vancouver

Jäger A, Stafford GI. Quality assessment of Tulbaghia rhizomes. South African Journal of Botany. 2012 Sep;82:92-98. https://doi.org/10.1016/j.sajb.2012.07.025

Author

Jäger, Anna ; Stafford, Gary Ivan. / Quality assessment of Tulbaghia rhizomes. In: South African Journal of Botany. 2012 ; Vol. 82. pp. 92-98.

Bibtex

@article{3785c8f62b5845dfbef58b456e7e7190,
title = "Quality assessment of Tulbaghia rhizomes",
abstract = "Tulbaghia species are used in traditional medicine in southern Africa. They contain sulphur compounds, which have anti-Candida activity. The sulphur compounds are unstable, so different extraction methods were investigated. Grinding the rhizome material in liquid nitrogen and extraction with ethanol yielded the best results. Eight Tulbaghia species were tested and found to contain the same pattern of sulphur compounds on the TLC plate, though in varying concentrations, except T. simmleri, for which sulphur compounds could not be detected. This means that more species can potentially be utilised for the drug Tulbaghiae rhizoma. A simple quantitative TLC dilution method was developed, which can be used to ascertain whether the rhizome material contains a sufficient level of sulphur compounds. The effect of storage was investigated. The content of sulphur compounds in the rhizomes decreased fast upon storage, half of the main compound was lost four weeks after harvest. Possible adulterants for Tulbaghiae rhizoma are Allium sativum and Agapanthus campanulatus. It was not possible to detect adulteration with A. sativum, but a simple TLC test could detect adulteration with 10 % A. campanulatus material.",
keywords = "Faculty of Science, Former Faculty of Pharmaceutical Sciences",
author = "Anna J{\"a}ger and Stafford, {Gary Ivan}",
year = "2012",
month = sep,
doi = "10.1016/j.sajb.2012.07.025",
language = "English",
volume = "82",
pages = "92--98",
journal = "South African Journal of Botany",
issn = "0254-6299",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Quality assessment of Tulbaghia rhizomes

AU - Jäger, Anna

AU - Stafford, Gary Ivan

PY - 2012/9

Y1 - 2012/9

N2 - Tulbaghia species are used in traditional medicine in southern Africa. They contain sulphur compounds, which have anti-Candida activity. The sulphur compounds are unstable, so different extraction methods were investigated. Grinding the rhizome material in liquid nitrogen and extraction with ethanol yielded the best results. Eight Tulbaghia species were tested and found to contain the same pattern of sulphur compounds on the TLC plate, though in varying concentrations, except T. simmleri, for which sulphur compounds could not be detected. This means that more species can potentially be utilised for the drug Tulbaghiae rhizoma. A simple quantitative TLC dilution method was developed, which can be used to ascertain whether the rhizome material contains a sufficient level of sulphur compounds. The effect of storage was investigated. The content of sulphur compounds in the rhizomes decreased fast upon storage, half of the main compound was lost four weeks after harvest. Possible adulterants for Tulbaghiae rhizoma are Allium sativum and Agapanthus campanulatus. It was not possible to detect adulteration with A. sativum, but a simple TLC test could detect adulteration with 10 % A. campanulatus material.

AB - Tulbaghia species are used in traditional medicine in southern Africa. They contain sulphur compounds, which have anti-Candida activity. The sulphur compounds are unstable, so different extraction methods were investigated. Grinding the rhizome material in liquid nitrogen and extraction with ethanol yielded the best results. Eight Tulbaghia species were tested and found to contain the same pattern of sulphur compounds on the TLC plate, though in varying concentrations, except T. simmleri, for which sulphur compounds could not be detected. This means that more species can potentially be utilised for the drug Tulbaghiae rhizoma. A simple quantitative TLC dilution method was developed, which can be used to ascertain whether the rhizome material contains a sufficient level of sulphur compounds. The effect of storage was investigated. The content of sulphur compounds in the rhizomes decreased fast upon storage, half of the main compound was lost four weeks after harvest. Possible adulterants for Tulbaghiae rhizoma are Allium sativum and Agapanthus campanulatus. It was not possible to detect adulteration with A. sativum, but a simple TLC test could detect adulteration with 10 % A. campanulatus material.

KW - Faculty of Science

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1016/j.sajb.2012.07.025

DO - 10.1016/j.sajb.2012.07.025

M3 - Journal article

VL - 82

SP - 92

EP - 98

JO - South African Journal of Botany

JF - South African Journal of Botany

SN - 0254-6299

ER -

ID: 40575525