Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention

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Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention. / Molero, José M; Moragas, Ana; González López-Valcárcel, Beatriz; Bjerrum, Lars; Cots, Josep M; Llor, Carl.

In: International Journal of Clinical Practice, Vol. 73, No. 5, e13312, 2019.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Molero, JM, Moragas, A, González López-Valcárcel, B, Bjerrum, L, Cots, JM & Llor, C 2019, 'Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention', International Journal of Clinical Practice, vol. 73, no. 5, e13312. https://doi.org/10.1111/ijcp.13312

APA

Molero, J. M., Moragas, A., González López-Valcárcel, B., Bjerrum, L., Cots, J. M., & Llor, C. (2019). Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention. International Journal of Clinical Practice, 73(5), [e13312]. https://doi.org/10.1111/ijcp.13312

Vancouver

Molero JM, Moragas A, González López-Valcárcel B, Bjerrum L, Cots JM, Llor C. Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention. International Journal of Clinical Practice. 2019;73(5). e13312. https://doi.org/10.1111/ijcp.13312

Author

Molero, José M ; Moragas, Ana ; González López-Valcárcel, Beatriz ; Bjerrum, Lars ; Cots, Josep M ; Llor, Carl. / Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention. In: International Journal of Clinical Practice. 2019 ; Vol. 73, No. 5.

Bibtex

@article{59229abba09d4db79f9e686d56396874,
title = "Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention",
abstract = "AIMS: Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out six years earlier.METHODS: GPs who had completed two registrations in 2008 and 2009 were again invited to participate in a third audit-based study in 2015. A multifaceted intervention was held one to three months before the second registration. A new group of GPs with no previous training on the rational use of antibiotics were also invited to participate and acted as controls. Multilevel logistic regression was performed considering the prescription of antibiotics as the dependent variable.RESULTS: A total of 121 GPs of the 210 who underwent the intervention (57.6{\%}) and 117 control GPs registered 4,333 episodes of LRTIs. On adjustment for covariables, compared to the antibiotic prescription for LRTIs observed just after the intervention, antibiotic prescription slightly increased six years later among GPs who had undergone the intervention (OR 1.17, 95{\%} CI 0.95-1.43), while control GPs prescribed significantly more antibiotics (OR 2.31, 95{\%} CI 1.62-3.29). However, withholding antibiotic prescribing with C-reactive protein (CRP) values < 10 mg/L was more frequently observed just after the intervention compared to six years later (12.7{\%} vs. 32.2{\%}; p < 0.01).CONCLUSIONS: Antibiotic prescribing for LRTIs remains low six years after an intervention, although GPs are less confident to withhold antibiotic therapy in patients with low CRP levels. This article is protected by copyright. All rights reserved.",
author = "Molero, {Jos{\'e} M} and Ana Moragas and {Gonz{\'a}lez L{\'o}pez-Valc{\'a}rcel}, Beatriz and Lars Bjerrum and Cots, {Josep M} and Carl Llor",
note = "This article is protected by copyright. All rights reserved.",
year = "2019",
doi = "10.1111/ijcp.13312",
language = "English",
volume = "73",
journal = "International Journal of Clinical Practice",
issn = "1368-5031",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Reducing antibiotic prescribing for lower respiratory tract infections six years after a multifaceted intervention

AU - Molero, José M

AU - Moragas, Ana

AU - González López-Valcárcel, Beatriz

AU - Bjerrum, Lars

AU - Cots, Josep M

AU - Llor, Carl

N1 - This article is protected by copyright. All rights reserved.

PY - 2019

Y1 - 2019

N2 - AIMS: Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out six years earlier.METHODS: GPs who had completed two registrations in 2008 and 2009 were again invited to participate in a third audit-based study in 2015. A multifaceted intervention was held one to three months before the second registration. A new group of GPs with no previous training on the rational use of antibiotics were also invited to participate and acted as controls. Multilevel logistic regression was performed considering the prescription of antibiotics as the dependent variable.RESULTS: A total of 121 GPs of the 210 who underwent the intervention (57.6%) and 117 control GPs registered 4,333 episodes of LRTIs. On adjustment for covariables, compared to the antibiotic prescription for LRTIs observed just after the intervention, antibiotic prescription slightly increased six years later among GPs who had undergone the intervention (OR 1.17, 95% CI 0.95-1.43), while control GPs prescribed significantly more antibiotics (OR 2.31, 95% CI 1.62-3.29). However, withholding antibiotic prescribing with C-reactive protein (CRP) values < 10 mg/L was more frequently observed just after the intervention compared to six years later (12.7% vs. 32.2%; p < 0.01).CONCLUSIONS: Antibiotic prescribing for LRTIs remains low six years after an intervention, although GPs are less confident to withhold antibiotic therapy in patients with low CRP levels. This article is protected by copyright. All rights reserved.

AB - AIMS: Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out six years earlier.METHODS: GPs who had completed two registrations in 2008 and 2009 were again invited to participate in a third audit-based study in 2015. A multifaceted intervention was held one to three months before the second registration. A new group of GPs with no previous training on the rational use of antibiotics were also invited to participate and acted as controls. Multilevel logistic regression was performed considering the prescription of antibiotics as the dependent variable.RESULTS: A total of 121 GPs of the 210 who underwent the intervention (57.6%) and 117 control GPs registered 4,333 episodes of LRTIs. On adjustment for covariables, compared to the antibiotic prescription for LRTIs observed just after the intervention, antibiotic prescription slightly increased six years later among GPs who had undergone the intervention (OR 1.17, 95% CI 0.95-1.43), while control GPs prescribed significantly more antibiotics (OR 2.31, 95% CI 1.62-3.29). However, withholding antibiotic prescribing with C-reactive protein (CRP) values < 10 mg/L was more frequently observed just after the intervention compared to six years later (12.7% vs. 32.2%; p < 0.01).CONCLUSIONS: Antibiotic prescribing for LRTIs remains low six years after an intervention, although GPs are less confident to withhold antibiotic therapy in patients with low CRP levels. This article is protected by copyright. All rights reserved.

U2 - 10.1111/ijcp.13312

DO - 10.1111/ijcp.13312

M3 - Journal article

VL - 73

JO - International Journal of Clinical Practice

JF - International Journal of Clinical Practice

SN - 1368-5031

IS - 5

M1 - e13312

ER -

ID: 212503833