Register-based studies of cardiovascular disease
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Register-based studies of cardiovascular disease. / Abildstrøm, Steen Z; Torp-Pedersen, Christian; Madsen, Mette.
In: Scandinavian Journal of Public Health, Vol. 39, No. Suppl 7, 2011, p. 165-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Register-based studies of cardiovascular disease
AU - Abildstrøm, Steen Z
AU - Torp-Pedersen, Christian
AU - Madsen, Mette
PY - 2011
Y1 - 2011
N2 - Introduction: The use of the unique personal identification number in the Nordic database systems enables the researchers to link the registers at the individual level. The registers can be used for both defining specific patient populations and to identify later events during follow-up. This review gives three examples within cardiovascular epidemiology to illustrate the use of the national administrative registers available to all researchers upon request. Research topics: The hospitalisation rate of acute myocardial infarction (AMI) was expected to be increased and case-fatality rate to decrease when the diagnostic criteria were changed in 2000. Linkage of national registers found a relative increase in hospitalisation rate of 14% while the case-fatality rate was unaffected. The pharmacological treatment of AMI patients was evaluated by linkage of administrative data. The use of evidence-based treatment increased significantly over time and adherence to treatment was high. Finally, use of specific nonsteroidal antiinflammatory drugs by healthy subjects was associated with a dose-dependent increase in cardiovascular risk. CONCLUSION: The nationwide registers have proven very useful in monitoring the hospitalisation rate and treatment of cardiovascular disease. The risk of unmeasured factors affecting the results calls for cautious interpretation of the results.
AB - Introduction: The use of the unique personal identification number in the Nordic database systems enables the researchers to link the registers at the individual level. The registers can be used for both defining specific patient populations and to identify later events during follow-up. This review gives three examples within cardiovascular epidemiology to illustrate the use of the national administrative registers available to all researchers upon request. Research topics: The hospitalisation rate of acute myocardial infarction (AMI) was expected to be increased and case-fatality rate to decrease when the diagnostic criteria were changed in 2000. Linkage of national registers found a relative increase in hospitalisation rate of 14% while the case-fatality rate was unaffected. The pharmacological treatment of AMI patients was evaluated by linkage of administrative data. The use of evidence-based treatment increased significantly over time and adherence to treatment was high. Finally, use of specific nonsteroidal antiinflammatory drugs by healthy subjects was associated with a dose-dependent increase in cardiovascular risk. CONCLUSION: The nationwide registers have proven very useful in monitoring the hospitalisation rate and treatment of cardiovascular disease. The risk of unmeasured factors affecting the results calls for cautious interpretation of the results.
U2 - 10.1177/1403494810396559
DO - 10.1177/1403494810396559
M3 - Journal article
C2 - 21775377
VL - 39
SP - 165
EP - 169
JO - Acta socio-medica Scandinavica
JF - Acta socio-medica Scandinavica
SN - 1403-4948
IS - Suppl 7
ER -
ID: 33852523