Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors
Research output: Contribution to journal › Journal article › Research › peer-review
The synthesis of four new isoxazoline-based amino acids being analogues of previously described glutamate receptor ligands is reported and their affinity for ionotropic glutamate receptors is analyzed in comparison with that of selected model compounds. Molecular modelling investigations have been carried out to rationalize the interaction with the NMDA receptors.
|Journal||European Journal of Medicinal Chemistry|
|Publication status||Published - 1 Feb 2011|
- The Faculty of Pharmaceutical Sciences