The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity: findings from the Danish Nurse Cohort

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Standard

The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity : findings from the Danish Nurse Cohort. / Hammer, Maria D.; Andersen, Amalie J.; Larsen, Sofus C.; Simonsen, Mette K.; Heitmann, Berit L.

In: International Journal of Obesity, Vol. 46, No. 2, 2022, p. 433-436.

Research output: Contribution to journal › Letter › Research › peer-review

Harvard

Hammer, MD, Andersen, AJ, Larsen, SC, Simonsen, MK & Heitmann, BL 2022, 'The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity: findings from the Danish Nurse Cohort', International Journal of Obesity, vol. 46, no. 2, pp. 433-436. https://doi.org/10.1038/s41366-021-00990-4

APA

Hammer, M. D., Andersen, A. J., Larsen, S. C., Simonsen, M. K., & Heitmann, B. L. (2022). The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity: findings from the Danish Nurse Cohort. International Journal of Obesity, 46(2), 433-436. https://doi.org/10.1038/s41366-021-00990-4

Vancouver

Hammer MD, Andersen AJ, Larsen SC, Simonsen MK, Heitmann BL. The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity: findings from the Danish Nurse Cohort. International Journal of Obesity. 2022;46(2):433-436. https://doi.org/10.1038/s41366-021-00990-4

Author

Hammer, Maria D. ; Andersen, Amalie J. ; Larsen, Sofus C. ; Simonsen, Mette K. ; Heitmann, Berit L. / The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity : findings from the Danish Nurse Cohort. In: International Journal of Obesity. 2022 ; Vol. 46, No. 2. pp. 433-436.

Bibtex

@article{862995a960c342549205103521f7adc2,
title = "The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity: findings from the Danish Nurse Cohort",
abstract = "Several studies show an increased risk of coronary heart disease (CHD) among people with obesity, but it is largely unknown whether this association also depends on a familial predisposition to obesity. This study examined if associations between Body Mass Index (BMI) or waist circumference (WC) and incident CHD differed among Danish female nurses with and without familial overweight and obesity. Analyses were based on data from the Danish Nurse Cohort (n = 20,701). Self-reported height, weight and self-measured WC were assessed in 1999, as was information on familial overweight/obesity, defined as having one or both parents with overweight/obesity. Information on the development of or death from CHD was collected from nationwide Danish registries in 2015. Analyses were based on Cox proportional hazard regression models adjusted for potential confounding factors. Both BMI and WC were directly associated with CHD risk, but we found no evidence of effect modification from familial predisposition to obesity. Hence a familial predisposition to obesity does not seem to influence the risk of CHD associated with general or central obesity.",
author = "Hammer, {Maria D.} and Andersen, {Amalie J.} and Larsen, {Sofus C.} and Simonsen, {Mette K.} and Heitmann, {Berit L.}",
year = "2022",
doi = "10.1038/s41366-021-00990-4",
language = "English",
volume = "46",
pages = "433--436",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "nature publishing group",
number = "2",

}

RIS

TY - JOUR

T1 - The association between general and central obesity and the risks of coronary heart disease in women with and without a familial predisposition to obesity

T2 - findings from the Danish Nurse Cohort

AU - Hammer, Maria D.

AU - Andersen, Amalie J.

AU - Larsen, Sofus C.

AU - Simonsen, Mette K.

AU - Heitmann, Berit L.

PY - 2022

Y1 - 2022

N2 - Several studies show an increased risk of coronary heart disease (CHD) among people with obesity, but it is largely unknown whether this association also depends on a familial predisposition to obesity. This study examined if associations between Body Mass Index (BMI) or waist circumference (WC) and incident CHD differed among Danish female nurses with and without familial overweight and obesity. Analyses were based on data from the Danish Nurse Cohort (n = 20,701). Self-reported height, weight and self-measured WC were assessed in 1999, as was information on familial overweight/obesity, defined as having one or both parents with overweight/obesity. Information on the development of or death from CHD was collected from nationwide Danish registries in 2015. Analyses were based on Cox proportional hazard regression models adjusted for potential confounding factors. Both BMI and WC were directly associated with CHD risk, but we found no evidence of effect modification from familial predisposition to obesity. Hence a familial predisposition to obesity does not seem to influence the risk of CHD associated with general or central obesity.

AB - Several studies show an increased risk of coronary heart disease (CHD) among people with obesity, but it is largely unknown whether this association also depends on a familial predisposition to obesity. This study examined if associations between Body Mass Index (BMI) or waist circumference (WC) and incident CHD differed among Danish female nurses with and without familial overweight and obesity. Analyses were based on data from the Danish Nurse Cohort (n = 20,701). Self-reported height, weight and self-measured WC were assessed in 1999, as was information on familial overweight/obesity, defined as having one or both parents with overweight/obesity. Information on the development of or death from CHD was collected from nationwide Danish registries in 2015. Analyses were based on Cox proportional hazard regression models adjusted for potential confounding factors. Both BMI and WC were directly associated with CHD risk, but we found no evidence of effect modification from familial predisposition to obesity. Hence a familial predisposition to obesity does not seem to influence the risk of CHD associated with general or central obesity.

U2 - 10.1038/s41366-021-00990-4

DO - 10.1038/s41366-021-00990-4

M3 - Letter

C2 - 34671107

VL - 46

SP - 433

EP - 436

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 2

ER -

ID: 282803386