The association of pre-pregnancy alcohol drinking with child neuropsychological functioning

Research output: Contribution to journalJournal articlepeer-review

Standard

The association of pre-pregnancy alcohol drinking with child neuropsychological functioning. / Kesmodel, Ulrik Schiøler; Kjaersgaard, M. I. S.; Denny, C. H.; Bertrand, J.; Skogerbø, A.; Eriksen, H-LF; Bay, B.; Underbjerg, M.; Mortensen, E. L.

In: B J O G, Vol. 122, No. 13, 12.2015, p. 1728-1738.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Kesmodel, US, Kjaersgaard, MIS, Denny, CH, Bertrand, J, Skogerbø, A, Eriksen, H-LF, Bay, B, Underbjerg, M & Mortensen, EL 2015, 'The association of pre-pregnancy alcohol drinking with child neuropsychological functioning', B J O G, vol. 122, no. 13, pp. 1728-1738. https://doi.org/10.1111/1471-0528.13172

APA

Kesmodel, U. S., Kjaersgaard, M. I. S., Denny, C. H., Bertrand, J., Skogerbø, A., Eriksen, H-LF., Bay, B., Underbjerg, M., & Mortensen, E. L. (2015). The association of pre-pregnancy alcohol drinking with child neuropsychological functioning. B J O G, 122(13), 1728-1738. https://doi.org/10.1111/1471-0528.13172

Vancouver

Kesmodel US, Kjaersgaard MIS, Denny CH, Bertrand J, Skogerbø A, Eriksen H-LF et al. The association of pre-pregnancy alcohol drinking with child neuropsychological functioning. B J O G. 2015 Dec;122(13):1728-1738. https://doi.org/10.1111/1471-0528.13172

Author

Kesmodel, Ulrik Schiøler ; Kjaersgaard, M. I. S. ; Denny, C. H. ; Bertrand, J. ; Skogerbø, A. ; Eriksen, H-LF ; Bay, B. ; Underbjerg, M. ; Mortensen, E. L. / The association of pre-pregnancy alcohol drinking with child neuropsychological functioning. In: B J O G. 2015 ; Vol. 122, No. 13. pp. 1728-1738.

Bibtex

@article{ceca7061d0534abd865d859e0895c329,
title = "The association of pre-pregnancy alcohol drinking with child neuropsychological functioning",
abstract = "Objective: To examine the effects of pre-pregnancy alcohol drinking on child neuropsychological functioning.Design: Prospective follow-up study.Setting and population: 154 women and their children sampled from the Danish National Birth Cohort.Methods: Participants were sampled based on maternal alcohol consumption before pregnancy. At 5 years of age, the children were tested with the Wechsler Preschool and Primary Scale of Intelligence-Revised, the Test of Everyday Attention for Children atFive (TEACh-5), and the Movement Assessment Battery for Children (MABC). The Behaviour Rating Inventory of Executive Function (BRIEF) was completed by the mothers and a preschool teacher. Parental education, maternal IQ, prenatal maternal smoking, child{\textquoteright}s age at testing, child{\textquoteright}s sex, and maternal alcohol intake during pregnancy were considered potential confounders.Main outcome measures: Performance on the Wechsler Preschool and Primary Scale of Intelligence-Revised, the TEACh-5, theMABC, and the BRIEF.Results: Intake of 15–21 drinks/week on average prior to pregnancy was not associated with any of the outcomes, but intake of ≥22 drinks/week on average was associated with a significantly lower adjusted mean full scale IQ and lower adjusted means in overall attention and sustained attention score, but not in selective attention score or any of the BRIEF index scores or MABC scores.Conclusions: Intake of ≥22 drinks/week before pregnancy was associated with lower mean full scale IQ, overall attention and sustained attention. Assessment of pre-pregnancy drinking provides additional information regarding potential prenatal alcohol exposure and its implications for child neurodevelopment.",
keywords = "Alcohol drinking, attention, executive function, intelligence, motor function, neurodevelopmental effects, pregnancy",
author = "Kesmodel, {Ulrik Schi{\o}ler} and Kjaersgaard, {M. I. S.} and Denny, {C. H.} and J. Bertrand and A. Skogerb{\o} and H-LF Eriksen and B. Bay and M. Underbjerg and Mortensen, {E. L.}",
year = "2015",
month = dec,
doi = "10.1111/1471-0528.13172",
language = "English",
volume = "122",
pages = "1728--1738",
journal = "BJOG: An International Journal of Obstetrics and Gynaecology",
issn = "0140-7686",
publisher = "Wiley-Blackwell",
number = "13",

}

RIS

TY - JOUR

T1 - The association of pre-pregnancy alcohol drinking with child neuropsychological functioning

AU - Kesmodel, Ulrik Schiøler

AU - Kjaersgaard, M. I. S.

AU - Denny, C. H.

AU - Bertrand, J.

AU - Skogerbø, A.

AU - Eriksen, H-LF

AU - Bay, B.

AU - Underbjerg, M.

AU - Mortensen, E. L.

PY - 2015/12

Y1 - 2015/12

N2 - Objective: To examine the effects of pre-pregnancy alcohol drinking on child neuropsychological functioning.Design: Prospective follow-up study.Setting and population: 154 women and their children sampled from the Danish National Birth Cohort.Methods: Participants were sampled based on maternal alcohol consumption before pregnancy. At 5 years of age, the children were tested with the Wechsler Preschool and Primary Scale of Intelligence-Revised, the Test of Everyday Attention for Children atFive (TEACh-5), and the Movement Assessment Battery for Children (MABC). The Behaviour Rating Inventory of Executive Function (BRIEF) was completed by the mothers and a preschool teacher. Parental education, maternal IQ, prenatal maternal smoking, child’s age at testing, child’s sex, and maternal alcohol intake during pregnancy were considered potential confounders.Main outcome measures: Performance on the Wechsler Preschool and Primary Scale of Intelligence-Revised, the TEACh-5, theMABC, and the BRIEF.Results: Intake of 15–21 drinks/week on average prior to pregnancy was not associated with any of the outcomes, but intake of ≥22 drinks/week on average was associated with a significantly lower adjusted mean full scale IQ and lower adjusted means in overall attention and sustained attention score, but not in selective attention score or any of the BRIEF index scores or MABC scores.Conclusions: Intake of ≥22 drinks/week before pregnancy was associated with lower mean full scale IQ, overall attention and sustained attention. Assessment of pre-pregnancy drinking provides additional information regarding potential prenatal alcohol exposure and its implications for child neurodevelopment.

AB - Objective: To examine the effects of pre-pregnancy alcohol drinking on child neuropsychological functioning.Design: Prospective follow-up study.Setting and population: 154 women and their children sampled from the Danish National Birth Cohort.Methods: Participants were sampled based on maternal alcohol consumption before pregnancy. At 5 years of age, the children were tested with the Wechsler Preschool and Primary Scale of Intelligence-Revised, the Test of Everyday Attention for Children atFive (TEACh-5), and the Movement Assessment Battery for Children (MABC). The Behaviour Rating Inventory of Executive Function (BRIEF) was completed by the mothers and a preschool teacher. Parental education, maternal IQ, prenatal maternal smoking, child’s age at testing, child’s sex, and maternal alcohol intake during pregnancy were considered potential confounders.Main outcome measures: Performance on the Wechsler Preschool and Primary Scale of Intelligence-Revised, the TEACh-5, theMABC, and the BRIEF.Results: Intake of 15–21 drinks/week on average prior to pregnancy was not associated with any of the outcomes, but intake of ≥22 drinks/week on average was associated with a significantly lower adjusted mean full scale IQ and lower adjusted means in overall attention and sustained attention score, but not in selective attention score or any of the BRIEF index scores or MABC scores.Conclusions: Intake of ≥22 drinks/week before pregnancy was associated with lower mean full scale IQ, overall attention and sustained attention. Assessment of pre-pregnancy drinking provides additional information regarding potential prenatal alcohol exposure and its implications for child neurodevelopment.

KW - Alcohol drinking

KW - attention

KW - executive function

KW - intelligence

KW - motor function

KW - neurodevelopmental effects

KW - pregnancy

U2 - 10.1111/1471-0528.13172

DO - 10.1111/1471-0528.13172

M3 - Journal article

C2 - 25395365

VL - 122

SP - 1728

EP - 1738

JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

SN - 0140-7686

IS - 13

ER -

ID: 160892584