The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database. / Janbek, Janet; Kriegbaum, Margit; Grand, Mia Klinten; Specht, Ina Olmer; Lind, Bent Struer; Andersen, Christen Lykkegaard; Heitmann, Berit Lilienthal.

In: BMJ Open, Vol. 10, No. 5, e034318, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Janbek, J, Kriegbaum, M, Grand, MK, Specht, IO, Lind, BS, Andersen, CL & Heitmann, BL 2020, 'The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database', BMJ Open, vol. 10, no. 5, e034318. https://doi.org/10.1136/bmjopen-2019-034318

APA

Janbek, J., Kriegbaum, M., Grand, M. K., Specht, I. O., Lind, B. S., Andersen, C. L., & Heitmann, B. L. (2020). The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database. BMJ Open, 10(5), [e034318]. https://doi.org/10.1136/bmjopen-2019-034318

Vancouver

Janbek J, Kriegbaum M, Grand MK, Specht IO, Lind BS, Andersen CL et al. The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database. BMJ Open. 2020;10(5). e034318. https://doi.org/10.1136/bmjopen-2019-034318

Author

Janbek, Janet ; Kriegbaum, Margit ; Grand, Mia Klinten ; Specht, Ina Olmer ; Lind, Bent Struer ; Andersen, Christen Lykkegaard ; Heitmann, Berit Lilienthal. / The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database. In: BMJ Open. 2020 ; Vol. 10, No. 5.

Bibtex

@article{5a41f4509fc94c2eae8cd6a11247a2c8,
title = "The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database",
abstract = "PURPOSE: The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database was established based on data from The Danish Medical Birth Register and the Copenhagen Primary Care Laboratory (CopLab) database. The aim was to provide a biomedical and epidemiological data resource for research in early disease programming (eg, parental clinical biomarker levels and pregnancy/ birth outcomes or long-term health in the offspring).PARTICIPANTS: The cohort consisted in total of 203 608 women (with 340 891 pregnancies) who gave birth to 348 248 children and with 200 590 related fathers. In this paper, we focused on women and fathers who had clinical test requisitions prior to and during pregnancy, and on all children. Thus, the cohort in focus consisted of 203 054 pregnancies with requisitions on 147 045 pregnant women, 39 815 fathers with requisitions during periconception and 65 315 children with requisitions.FINDINGS TO DATE: In addition to information on pregnancy and birth health status and general socio-demographic data, over 2.2 million clinically relevant test results were available for pregnancies with requisitions, over 1.5 million for children and over 600 000 test results were available for the fathers with requisitions during periconception. These were ordered by general practitioners in the primary care setting only and included general blood tests, nutritional biomarkers (macronutrients and micronutrients) and hormone tests. Information on tests related to infections, allergies, heart and lung function and sperm analyses (fathers) were also available.FUTURE PLANS: The CopPreg database provides ready to use and valid data from already collected, objectively measured and analysed clinical tests. With several research projects planned, we further invite national and international researchers to use this vast data resource. In a coming paper, we will explore and discuss the indication bias in our cohort.",
author = "Janet Janbek and Margit Kriegbaum and Grand, {Mia Klinten} and Specht, {Ina Olmer} and Lind, {Bent Struer} and Andersen, {Christen Lykkegaard} and Heitmann, {Berit Lilienthal}",
note = "{\textcopyright} Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",
year = "2020",
doi = "10.1136/bmjopen-2019-034318",
language = "English",
volume = "10",
journal = "BMJ Open",
issn = "2044-6055",
publisher = "BMJ Publishing Group",
number = "5",

}

RIS

TY - JOUR

T1 - The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database

AU - Janbek, Janet

AU - Kriegbaum, Margit

AU - Grand, Mia Klinten

AU - Specht, Ina Olmer

AU - Lind, Bent Struer

AU - Andersen, Christen Lykkegaard

AU - Heitmann, Berit Lilienthal

N1 - © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2020

Y1 - 2020

N2 - PURPOSE: The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database was established based on data from The Danish Medical Birth Register and the Copenhagen Primary Care Laboratory (CopLab) database. The aim was to provide a biomedical and epidemiological data resource for research in early disease programming (eg, parental clinical biomarker levels and pregnancy/ birth outcomes or long-term health in the offspring).PARTICIPANTS: The cohort consisted in total of 203 608 women (with 340 891 pregnancies) who gave birth to 348 248 children and with 200 590 related fathers. In this paper, we focused on women and fathers who had clinical test requisitions prior to and during pregnancy, and on all children. Thus, the cohort in focus consisted of 203 054 pregnancies with requisitions on 147 045 pregnant women, 39 815 fathers with requisitions during periconception and 65 315 children with requisitions.FINDINGS TO DATE: In addition to information on pregnancy and birth health status and general socio-demographic data, over 2.2 million clinically relevant test results were available for pregnancies with requisitions, over 1.5 million for children and over 600 000 test results were available for the fathers with requisitions during periconception. These were ordered by general practitioners in the primary care setting only and included general blood tests, nutritional biomarkers (macronutrients and micronutrients) and hormone tests. Information on tests related to infections, allergies, heart and lung function and sperm analyses (fathers) were also available.FUTURE PLANS: The CopPreg database provides ready to use and valid data from already collected, objectively measured and analysed clinical tests. With several research projects planned, we further invite national and international researchers to use this vast data resource. In a coming paper, we will explore and discuss the indication bias in our cohort.

AB - PURPOSE: The Copenhagen Primary Care Laboratory Pregnancy (CopPreg) database was established based on data from The Danish Medical Birth Register and the Copenhagen Primary Care Laboratory (CopLab) database. The aim was to provide a biomedical and epidemiological data resource for research in early disease programming (eg, parental clinical biomarker levels and pregnancy/ birth outcomes or long-term health in the offspring).PARTICIPANTS: The cohort consisted in total of 203 608 women (with 340 891 pregnancies) who gave birth to 348 248 children and with 200 590 related fathers. In this paper, we focused on women and fathers who had clinical test requisitions prior to and during pregnancy, and on all children. Thus, the cohort in focus consisted of 203 054 pregnancies with requisitions on 147 045 pregnant women, 39 815 fathers with requisitions during periconception and 65 315 children with requisitions.FINDINGS TO DATE: In addition to information on pregnancy and birth health status and general socio-demographic data, over 2.2 million clinically relevant test results were available for pregnancies with requisitions, over 1.5 million for children and over 600 000 test results were available for the fathers with requisitions during periconception. These were ordered by general practitioners in the primary care setting only and included general blood tests, nutritional biomarkers (macronutrients and micronutrients) and hormone tests. Information on tests related to infections, allergies, heart and lung function and sperm analyses (fathers) were also available.FUTURE PLANS: The CopPreg database provides ready to use and valid data from already collected, objectively measured and analysed clinical tests. With several research projects planned, we further invite national and international researchers to use this vast data resource. In a coming paper, we will explore and discuss the indication bias in our cohort.

U2 - 10.1136/bmjopen-2019-034318

DO - 10.1136/bmjopen-2019-034318

M3 - Journal article

C2 - 32448791

VL - 10

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 5

M1 - e034318

ER -

ID: 241938878