The relationship between self-reported general health and observed depression and anxiety in cancer patients during chemotherapy
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The relationship between self-reported general health and observed depression and anxiety in cancer patients during chemotherapy. / Middelboe, Thomas; Ovesen, Lars; Mortensen, Erik Lykke; Bech, Per.
In: Nordic Journal of Psychiatry, Vol. 49, No. 1, 1995, p. 25-31.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The relationship between self-reported general health and observed depression and anxiety in cancer patients during chemotherapy
AU - Middelboe, Thomas
AU - Ovesen, Lars
AU - Mortensen, Erik Lykke
AU - Bech, Per
N1 - Funding Information: Acknowledgements - This study was supported by the Danish Cancer Society, @ant 89-402. The authors want to thank Dr. Mogens Gmnvold for critical comments to an earlier version of this manuscript.
PY - 1995
Y1 - 1995
N2 - In a prospective follow-up study of 30 patients before and during intermittent chemotherapy for solid malignancies, depression and anxiety were assessed with the Hamilton rating scales, and self-reported general health was measured by the General Health Questionnaire (GHQ), Functional Living Index-Cancer (FLIC), and Quality of Life Index (QLI). There were no significant changes in levels of psychopathology or self-reported health after 3 months of chemotherapy, but a significant decrease in Hamilton scores was seen after 6 months among patients responding favorably to chemotherapy. Although states of depression and anxiety occurred in more than 40% of the patients, they were not adequately detected with the GHQ when using the recommended threshold score. Moreover, the commonly used FLIC and QLI were only moderately associated with observer ratings for anxiety and depression. The health-related quality of life concept is discussed, and the risk of neglecting signs of significant psychopathology in cancer patients is emphasized. It is suggested that screening for depression in cancer patients should be performed routinely.
AB - In a prospective follow-up study of 30 patients before and during intermittent chemotherapy for solid malignancies, depression and anxiety were assessed with the Hamilton rating scales, and self-reported general health was measured by the General Health Questionnaire (GHQ), Functional Living Index-Cancer (FLIC), and Quality of Life Index (QLI). There were no significant changes in levels of psychopathology or self-reported health after 3 months of chemotherapy, but a significant decrease in Hamilton scores was seen after 6 months among patients responding favorably to chemotherapy. Although states of depression and anxiety occurred in more than 40% of the patients, they were not adequately detected with the GHQ when using the recommended threshold score. Moreover, the commonly used FLIC and QLI were only moderately associated with observer ratings for anxiety and depression. The health-related quality of life concept is discussed, and the risk of neglecting signs of significant psychopathology in cancer patients is emphasized. It is suggested that screening for depression in cancer patients should be performed routinely.
KW - Anxiety
KW - Cancer
KW - Depression
KW - General health
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84907137821&partnerID=8YFLogxK
U2 - 10.3109/08039489509011880
DO - 10.3109/08039489509011880
M3 - Journal article
AN - SCOPUS:84907137821
VL - 49
SP - 25
EP - 31
JO - Nordisk Psykiatrisk Tidsskrift
JF - Nordisk Psykiatrisk Tidsskrift
SN - 0803-9496
IS - 1
ER -
ID: 275901103