Trend in antibiotic prescription to children aged 0-6 years old in the capital region of Denmark between 2009 and 2018: Differences between municipalities and association with socioeconomic composition
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Trend in antibiotic prescription to children aged 0-6 years old in the capital region of Denmark between 2009 and 2018 : Differences between municipalities and association with socioeconomic composition. / Larsen, Sif Binder; Jensen, Maria Louise Veimer; Bjerrum, Lars; Siersma, Volkert; Bang, Christine Winther; Jensen, Jette Nygaard.
In: The European Journal of General Practice, Vol. 27, No. 1, 2021, p. 257-263.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Trend in antibiotic prescription to children aged 0-6 years old in the capital region of Denmark between 2009 and 2018
T2 - Differences between municipalities and association with socioeconomic composition
AU - Larsen, Sif Binder
AU - Jensen, Maria Louise Veimer
AU - Bjerrum, Lars
AU - Siersma, Volkert
AU - Bang, Christine Winther
AU - Jensen, Jette Nygaard
PY - 2021
Y1 - 2021
N2 - BACKGROUND: To curb future antibiotic resistance it is important to monitor and investigate current prescription patterns of antibiotics.OBJECTIVES: To examine trends in antibiotic prescription to children aged 0-6 years old and the association with socioeconomic status of municipalities in the Capital region of Denmark between 2009 and 2018.METHODS: This is a register-based study combining data on antibiotic treatments from 2009 to 2018, inhabitant-data and socioeconomic municipality scores. Subjects were children aged 0-6 years, residing in the Capital Region of Denmark. The study quantifies the use of antibiotics as number of antibiotic treatments/1000 inhabitants/year (TIY), inhabitants defined as children aged 0-6. Socioeconomic status of the municipalities is evaluated by a score from 3 to 12.RESULTS: The average TIY of the municipalities decreased from 741.2 [95%CI 689.3-793.2] in 2009 to 348.9 [329.4-368.4] in 2018. The difference between the highest and lowest prescribing municipalities was reduced from 648.3 TIY in 2009-212.5 TIY in 2018. The average increase in TIY per unit increase in socioeconomic municipality score changed from 20.05 [7.69-31.06] in 2009 to -4.58 [-16.02-5.60] in 2018, representing a decreasing association between socioeconomic municipality score and use of antibiotic in the respective municipalities.CONCLUSION: The trend in antibiotic prescription to children aged 0-6 years old decreased substantially in all the investigated municipalities in the 10-year study period. Local differences in prescription rates declined towards a more uniform prescription pattern across municipalities and association with socioeconomic status of the municipalities was reduced.
AB - BACKGROUND: To curb future antibiotic resistance it is important to monitor and investigate current prescription patterns of antibiotics.OBJECTIVES: To examine trends in antibiotic prescription to children aged 0-6 years old and the association with socioeconomic status of municipalities in the Capital region of Denmark between 2009 and 2018.METHODS: This is a register-based study combining data on antibiotic treatments from 2009 to 2018, inhabitant-data and socioeconomic municipality scores. Subjects were children aged 0-6 years, residing in the Capital Region of Denmark. The study quantifies the use of antibiotics as number of antibiotic treatments/1000 inhabitants/year (TIY), inhabitants defined as children aged 0-6. Socioeconomic status of the municipalities is evaluated by a score from 3 to 12.RESULTS: The average TIY of the municipalities decreased from 741.2 [95%CI 689.3-793.2] in 2009 to 348.9 [329.4-368.4] in 2018. The difference between the highest and lowest prescribing municipalities was reduced from 648.3 TIY in 2009-212.5 TIY in 2018. The average increase in TIY per unit increase in socioeconomic municipality score changed from 20.05 [7.69-31.06] in 2009 to -4.58 [-16.02-5.60] in 2018, representing a decreasing association between socioeconomic municipality score and use of antibiotic in the respective municipalities.CONCLUSION: The trend in antibiotic prescription to children aged 0-6 years old decreased substantially in all the investigated municipalities in the 10-year study period. Local differences in prescription rates declined towards a more uniform prescription pattern across municipalities and association with socioeconomic status of the municipalities was reduced.
U2 - 10.1080/13814788.2021.1965121
DO - 10.1080/13814788.2021.1965121
M3 - Journal article
C2 - 34486909
VL - 27
SP - 257
EP - 263
JO - European Journal of General Practice
JF - European Journal of General Practice
SN - 1381-4788
IS - 1
ER -
ID: 279252814