Use of non-prescription analgesics and male reproductive function

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Standard

Use of non-prescription analgesics and male reproductive function. / Høyer, B. B.; Ramlau-Hansen, C. H.; Bonde, J. P.; Larsen, S. B.; Toft, G.

In: Reproductive Toxicology, Vol. 74, 12.2017, p. 70-76.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Høyer, BB, Ramlau-Hansen, CH, Bonde, JP, Larsen, SB & Toft, G 2017, 'Use of non-prescription analgesics and male reproductive function', Reproductive Toxicology, vol. 74, pp. 70-76. https://doi.org/10.1016/j.reprotox.2017.09.004

APA

Høyer, B. B., Ramlau-Hansen, C. H., Bonde, J. P., Larsen, S. B., & Toft, G. (2017). Use of non-prescription analgesics and male reproductive function. Reproductive Toxicology, 74, 70-76. https://doi.org/10.1016/j.reprotox.2017.09.004

Vancouver

Høyer BB, Ramlau-Hansen CH, Bonde JP, Larsen SB, Toft G. Use of non-prescription analgesics and male reproductive function. Reproductive Toxicology. 2017 Dec;74:70-76. https://doi.org/10.1016/j.reprotox.2017.09.004

Author

Høyer, B. B. ; Ramlau-Hansen, C. H. ; Bonde, J. P. ; Larsen, S. B. ; Toft, G. / Use of non-prescription analgesics and male reproductive function. In: Reproductive Toxicology. 2017 ; Vol. 74. pp. 70-76.

Bibtex

@article{68009ef2607246339f3ed11fbf4c73fa,
title = "Use of non-prescription analgesics and male reproductive function",
abstract = "We studied the association between intake of non-prescription analgesics and semen quality and male reproductive hormone levels in a cross-sectional study among 1493 men. The men provided one semen (n = 1493) and blood sample (n = 1056) and filled in questionnaires on use of non-prescription analgesics (paracetamol, NSAIDs and combination drugs (yes/no)). Adjusting for age, study and other covariates, we observed no association between intake of non-prescription analgesics and markers of semen quality. Adjusting for age and time of day of blood sampling, users of non-prescription analgesics had a 10.4{\%} (95{\%} confidence interval (CI) 4.0–17.1{\%}) higher testosterone level than non-users. When we stratified by medication type, the association between analgesics and higher testosterone was observed between users of non-steroidal anti-inflammatory drugs (NSAIDs) and combination drugs but not paracetamol. This study suggests that use of non-prescription analgesics is associated with slightly higher serum testosterone levels than non-use.",
keywords = "Gonadal steroid hormones, Non-steroidal anti-inflammatory drugs, Paracetamol, Reproductive health, Semen analysis",
author = "H{\o}yer, {B. B.} and Ramlau-Hansen, {C. H.} and Bonde, {J. P.} and Larsen, {S. B.} and G. Toft",
year = "2017",
month = "12",
doi = "10.1016/j.reprotox.2017.09.004",
language = "English",
volume = "74",
pages = "70--76",
journal = "Reproductive Toxicology",
issn = "0890-6238",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Use of non-prescription analgesics and male reproductive function

AU - Høyer, B. B.

AU - Ramlau-Hansen, C. H.

AU - Bonde, J. P.

AU - Larsen, S. B.

AU - Toft, G.

PY - 2017/12

Y1 - 2017/12

N2 - We studied the association between intake of non-prescription analgesics and semen quality and male reproductive hormone levels in a cross-sectional study among 1493 men. The men provided one semen (n = 1493) and blood sample (n = 1056) and filled in questionnaires on use of non-prescription analgesics (paracetamol, NSAIDs and combination drugs (yes/no)). Adjusting for age, study and other covariates, we observed no association between intake of non-prescription analgesics and markers of semen quality. Adjusting for age and time of day of blood sampling, users of non-prescription analgesics had a 10.4% (95% confidence interval (CI) 4.0–17.1%) higher testosterone level than non-users. When we stratified by medication type, the association between analgesics and higher testosterone was observed between users of non-steroidal anti-inflammatory drugs (NSAIDs) and combination drugs but not paracetamol. This study suggests that use of non-prescription analgesics is associated with slightly higher serum testosterone levels than non-use.

AB - We studied the association between intake of non-prescription analgesics and semen quality and male reproductive hormone levels in a cross-sectional study among 1493 men. The men provided one semen (n = 1493) and blood sample (n = 1056) and filled in questionnaires on use of non-prescription analgesics (paracetamol, NSAIDs and combination drugs (yes/no)). Adjusting for age, study and other covariates, we observed no association between intake of non-prescription analgesics and markers of semen quality. Adjusting for age and time of day of blood sampling, users of non-prescription analgesics had a 10.4% (95% confidence interval (CI) 4.0–17.1%) higher testosterone level than non-users. When we stratified by medication type, the association between analgesics and higher testosterone was observed between users of non-steroidal anti-inflammatory drugs (NSAIDs) and combination drugs but not paracetamol. This study suggests that use of non-prescription analgesics is associated with slightly higher serum testosterone levels than non-use.

KW - Gonadal steroid hormones

KW - Non-steroidal anti-inflammatory drugs

KW - Paracetamol

KW - Reproductive health

KW - Semen analysis

UR - http://www.scopus.com/inward/record.url?scp=85029372256&partnerID=8YFLogxK

U2 - 10.1016/j.reprotox.2017.09.004

DO - 10.1016/j.reprotox.2017.09.004

M3 - Journal article

VL - 74

SP - 70

EP - 76

JO - Reproductive Toxicology

JF - Reproductive Toxicology

SN - 0890-6238

ER -

ID: 188744192