Use of opioids in a danish population-based cohort of cancer patients

Research output: Contribution to journalJournal articlepeer-review

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Use of opioids in a danish population-based cohort of cancer patients. / Jarlbaek, Lene; Andersen, Morten; Hallas, Jesper; Engholm, Gerda; Kragstrup, Jakob.

In: Journal of Pain and Symptom Management, Vol. 29, No. 4, 04.2005, p. 336-343.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Jarlbaek, L, Andersen, M, Hallas, J, Engholm, G & Kragstrup, J 2005, 'Use of opioids in a danish population-based cohort of cancer patients', Journal of Pain and Symptom Management, vol. 29, no. 4, pp. 336-343. https://doi.org/10.1016/j.jpainsymman.2004.07.010

APA

Jarlbaek, L., Andersen, M., Hallas, J., Engholm, G., & Kragstrup, J. (2005). Use of opioids in a danish population-based cohort of cancer patients. Journal of Pain and Symptom Management, 29(4), 336-343. https://doi.org/10.1016/j.jpainsymman.2004.07.010

Vancouver

Jarlbaek L, Andersen M, Hallas J, Engholm G, Kragstrup J. Use of opioids in a danish population-based cohort of cancer patients. Journal of Pain and Symptom Management. 2005 Apr;29(4):336-343. https://doi.org/10.1016/j.jpainsymman.2004.07.010

Author

Jarlbaek, Lene ; Andersen, Morten ; Hallas, Jesper ; Engholm, Gerda ; Kragstrup, Jakob. / Use of opioids in a danish population-based cohort of cancer patients. In: Journal of Pain and Symptom Management. 2005 ; Vol. 29, No. 4. pp. 336-343.

Bibtex

@article{3cd94710f5564ed6a1993fad01d9785d,
title = "Use of opioids in a danish population-based cohort of cancer patients",
abstract = "Until recently, Denmark has had the highest use of strong opioids per capita in the world. Our aim was to analyze cancer patients' use of opioids in this population by linkage between the Danish Cancer Register and a prescription database. The changes in opioid use from 1994 to 1998 in the entire cohort of cancer patients (n = 24,190) in a Danish county (n ∼ 470,000) were analyzed. The overall consumption of opioids increased from 20 kg to 37 kg oral morphine equivalents (omeq) per year. The average consumption increased from 7.6 to 10.7g omeq/opioid user/year. The annual proportion of users increased from 17% to 20%. The proportion of patients who were alive 2 years after their first opioid prescription increased from 38% to 55%. Increased awareness towards pain treatment, with earlier initiation of opioid treatment and higher doses to the cancer patients, could be major explanations for the increase in the cancer patients' use of opioids.",
keywords = "Cancer pain, Danish Cancer Register, OPED, Opioids, Oral morphine equivalents, Pain treatment, Pharmacoepidemiological, Population-based, Tramadol, Transdermal fentanyl",
author = "Lene Jarlbaek and Morten Andersen and Jesper Hallas and Gerda Engholm and Jakob Kragstrup",
note = "Funding Information: This study was supported by grants from the Danish Cancer Society. There is no conflict of interest. ",
year = "2005",
month = apr,
doi = "10.1016/j.jpainsymman.2004.07.010",
language = "English",
volume = "29",
pages = "336--343",
journal = "Journal of Pain and Symptom Management",
issn = "0885-3924",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Use of opioids in a danish population-based cohort of cancer patients

AU - Jarlbaek, Lene

AU - Andersen, Morten

AU - Hallas, Jesper

AU - Engholm, Gerda

AU - Kragstrup, Jakob

N1 - Funding Information: This study was supported by grants from the Danish Cancer Society. There is no conflict of interest.

PY - 2005/4

Y1 - 2005/4

N2 - Until recently, Denmark has had the highest use of strong opioids per capita in the world. Our aim was to analyze cancer patients' use of opioids in this population by linkage between the Danish Cancer Register and a prescription database. The changes in opioid use from 1994 to 1998 in the entire cohort of cancer patients (n = 24,190) in a Danish county (n ∼ 470,000) were analyzed. The overall consumption of opioids increased from 20 kg to 37 kg oral morphine equivalents (omeq) per year. The average consumption increased from 7.6 to 10.7g omeq/opioid user/year. The annual proportion of users increased from 17% to 20%. The proportion of patients who were alive 2 years after their first opioid prescription increased from 38% to 55%. Increased awareness towards pain treatment, with earlier initiation of opioid treatment and higher doses to the cancer patients, could be major explanations for the increase in the cancer patients' use of opioids.

AB - Until recently, Denmark has had the highest use of strong opioids per capita in the world. Our aim was to analyze cancer patients' use of opioids in this population by linkage between the Danish Cancer Register and a prescription database. The changes in opioid use from 1994 to 1998 in the entire cohort of cancer patients (n = 24,190) in a Danish county (n ∼ 470,000) were analyzed. The overall consumption of opioids increased from 20 kg to 37 kg oral morphine equivalents (omeq) per year. The average consumption increased from 7.6 to 10.7g omeq/opioid user/year. The annual proportion of users increased from 17% to 20%. The proportion of patients who were alive 2 years after their first opioid prescription increased from 38% to 55%. Increased awareness towards pain treatment, with earlier initiation of opioid treatment and higher doses to the cancer patients, could be major explanations for the increase in the cancer patients' use of opioids.

KW - Cancer pain

KW - Danish Cancer Register

KW - OPED

KW - Opioids

KW - Oral morphine equivalents

KW - Pain treatment

KW - Pharmacoepidemiological

KW - Population-based

KW - Tramadol

KW - Transdermal fentanyl

UR - http://www.scopus.com/inward/record.url?scp=18044363090&partnerID=8YFLogxK

U2 - 10.1016/j.jpainsymman.2004.07.010

DO - 10.1016/j.jpainsymman.2004.07.010

M3 - Journal article

C2 - 15857736

AN - SCOPUS:18044363090

VL - 29

SP - 336

EP - 343

JO - Journal of Pain and Symptom Management

JF - Journal of Pain and Symptom Management

SN - 0885-3924

IS - 4

ER -

ID: 324168655