Variation in detection of ductal carcinoma in situ during screening mammography: a survey within the International Cancer Screening Network

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Variation in detection of ductal carcinoma in situ during screening mammography : a survey within the International Cancer Screening Network. / Lynge, Elsebeth; Ponti, Antonio; James, Ted; Májek, Ondřej; von Euler-Chelpin, My; Anttila, Ahti; Fitzpatrick, Patricia; Frigerio, Alfonso; Kawai, Masaaki; Scharpantgen, Astrid; Broeders, Mireille; Hofvind, Solveig; Vidal, Carmen; Ederra, Maria; Salas, Dolores; Bulliard, Jean-Luc; Tomatis, Mariano; Kerlikowske, Karla; Taplin, Stephen; ICSN DCIS Working group.

In: European journal of cancer (Oxford, England : 1990), Vol. 50, No. 1, 01.2014, p. 185-92.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Lynge, E, Ponti, A, James, T, Májek, O, von Euler-Chelpin, M, Anttila, A, Fitzpatrick, P, Frigerio, A, Kawai, M, Scharpantgen, A, Broeders, M, Hofvind, S, Vidal, C, Ederra, M, Salas, D, Bulliard, J-L, Tomatis, M, Kerlikowske, K, Taplin, S & ICSN DCIS Working group 2014, 'Variation in detection of ductal carcinoma in situ during screening mammography: a survey within the International Cancer Screening Network', European journal of cancer (Oxford, England : 1990), vol. 50, no. 1, pp. 185-92. https://doi.org/10.1016/j.ejca.2013.08.013

APA

Lynge, E., Ponti, A., James, T., Májek, O., von Euler-Chelpin, M., Anttila, A., ... ICSN DCIS Working group (2014). Variation in detection of ductal carcinoma in situ during screening mammography: a survey within the International Cancer Screening Network. European journal of cancer (Oxford, England : 1990), 50(1), 185-92. https://doi.org/10.1016/j.ejca.2013.08.013

Vancouver

Lynge E, Ponti A, James T, Májek O, von Euler-Chelpin M, Anttila A et al. Variation in detection of ductal carcinoma in situ during screening mammography: a survey within the International Cancer Screening Network. European journal of cancer (Oxford, England : 1990). 2014 Jan;50(1):185-92. https://doi.org/10.1016/j.ejca.2013.08.013

Author

Lynge, Elsebeth ; Ponti, Antonio ; James, Ted ; Májek, Ondřej ; von Euler-Chelpin, My ; Anttila, Ahti ; Fitzpatrick, Patricia ; Frigerio, Alfonso ; Kawai, Masaaki ; Scharpantgen, Astrid ; Broeders, Mireille ; Hofvind, Solveig ; Vidal, Carmen ; Ederra, Maria ; Salas, Dolores ; Bulliard, Jean-Luc ; Tomatis, Mariano ; Kerlikowske, Karla ; Taplin, Stephen ; ICSN DCIS Working group. / Variation in detection of ductal carcinoma in situ during screening mammography : a survey within the International Cancer Screening Network. In: European journal of cancer (Oxford, England : 1990). 2014 ; Vol. 50, No. 1. pp. 185-92.

Bibtex

@article{13e16b115b7f4add9b97b93c0cff74e1,
title = "Variation in detection of ductal carcinoma in situ during screening mammography: a survey within the International Cancer Screening Network",
abstract = "BACKGROUND: There is concern about detection of ductal carcinoma in situ (DCIS) in screening mammography. DCIS accounts for a substantial proportion of screen-detected lesions but its effect on breast cancer mortality is debated. The International Cancer Screening Network conducted a comparative analysis to determine variation in DCIS detection.PATIENTS AND METHODS: Data were collected during 2004-2008 on number of screening examinations, detected breast cancers, DCIS cases and Globocan 2008 breast cancer incidence rates derived from national or regional cancer registers. We calculated screen-detection rates for breast cancers and DCIS.RESULTS: Data were obtained from 15 screening settings in 12 countries; 7,176,050 screening examinations; 29,605 breast cancers and 5324 DCIS cases. The ratio between highest and lowest breast cancer incidence was 2.88 (95{\%} confidence interval (CI) 2.76-3.00); 2.97 (95{\%} CI 2.51-3.51) for detection of breast cancer; and 3.49 (95{\%} CI 2.70-4.51) for detection of DCIS.CONCLUSIONS: Considerable international variation was found in DCIS detection. This variation could not be fully explained by variation in incidence nor in breast cancer detection rates. It suggests the potential for wide discrepancies in management of DCIS resulting in overtreatment of indolent DCIS or undertreatment of potentially curable disease. Comprehensive cancer registration is needed to monitor DCIS detection. Efforts to understand discrepancies and standardise management may improve care.",
keywords = "Aged, Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating, Data Collection, Early Detection of Cancer, Europe, Female, Humans, Mammography, Middle Aged, United States",
author = "Elsebeth Lynge and Antonio Ponti and Ted James and Ondřej M{\'a}jek and {von Euler-Chelpin}, My and Ahti Anttila and Patricia Fitzpatrick and Alfonso Frigerio and Masaaki Kawai and Astrid Scharpantgen and Mireille Broeders and Solveig Hofvind and Carmen Vidal and Maria Ederra and Dolores Salas and Jean-Luc Bulliard and Mariano Tomatis and Karla Kerlikowske and Stephen Taplin and {ICSN DCIS Working group}",
note = "Copyright {\circledC} 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.",
year = "2014",
month = "1",
doi = "10.1016/j.ejca.2013.08.013",
language = "English",
volume = "50",
pages = "185--92",
journal = "European Journal of Cancer",
issn = "0959-8049",
publisher = "Pergamon",
number = "1",

}

RIS

TY - JOUR

T1 - Variation in detection of ductal carcinoma in situ during screening mammography

T2 - a survey within the International Cancer Screening Network

AU - Lynge, Elsebeth

AU - Ponti, Antonio

AU - James, Ted

AU - Májek, Ondřej

AU - von Euler-Chelpin, My

AU - Anttila, Ahti

AU - Fitzpatrick, Patricia

AU - Frigerio, Alfonso

AU - Kawai, Masaaki

AU - Scharpantgen, Astrid

AU - Broeders, Mireille

AU - Hofvind, Solveig

AU - Vidal, Carmen

AU - Ederra, Maria

AU - Salas, Dolores

AU - Bulliard, Jean-Luc

AU - Tomatis, Mariano

AU - Kerlikowske, Karla

AU - Taplin, Stephen

AU - ICSN DCIS Working group

N1 - Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

PY - 2014/1

Y1 - 2014/1

N2 - BACKGROUND: There is concern about detection of ductal carcinoma in situ (DCIS) in screening mammography. DCIS accounts for a substantial proportion of screen-detected lesions but its effect on breast cancer mortality is debated. The International Cancer Screening Network conducted a comparative analysis to determine variation in DCIS detection.PATIENTS AND METHODS: Data were collected during 2004-2008 on number of screening examinations, detected breast cancers, DCIS cases and Globocan 2008 breast cancer incidence rates derived from national or regional cancer registers. We calculated screen-detection rates for breast cancers and DCIS.RESULTS: Data were obtained from 15 screening settings in 12 countries; 7,176,050 screening examinations; 29,605 breast cancers and 5324 DCIS cases. The ratio between highest and lowest breast cancer incidence was 2.88 (95% confidence interval (CI) 2.76-3.00); 2.97 (95% CI 2.51-3.51) for detection of breast cancer; and 3.49 (95% CI 2.70-4.51) for detection of DCIS.CONCLUSIONS: Considerable international variation was found in DCIS detection. This variation could not be fully explained by variation in incidence nor in breast cancer detection rates. It suggests the potential for wide discrepancies in management of DCIS resulting in overtreatment of indolent DCIS or undertreatment of potentially curable disease. Comprehensive cancer registration is needed to monitor DCIS detection. Efforts to understand discrepancies and standardise management may improve care.

AB - BACKGROUND: There is concern about detection of ductal carcinoma in situ (DCIS) in screening mammography. DCIS accounts for a substantial proportion of screen-detected lesions but its effect on breast cancer mortality is debated. The International Cancer Screening Network conducted a comparative analysis to determine variation in DCIS detection.PATIENTS AND METHODS: Data were collected during 2004-2008 on number of screening examinations, detected breast cancers, DCIS cases and Globocan 2008 breast cancer incidence rates derived from national or regional cancer registers. We calculated screen-detection rates for breast cancers and DCIS.RESULTS: Data were obtained from 15 screening settings in 12 countries; 7,176,050 screening examinations; 29,605 breast cancers and 5324 DCIS cases. The ratio between highest and lowest breast cancer incidence was 2.88 (95% confidence interval (CI) 2.76-3.00); 2.97 (95% CI 2.51-3.51) for detection of breast cancer; and 3.49 (95% CI 2.70-4.51) for detection of DCIS.CONCLUSIONS: Considerable international variation was found in DCIS detection. This variation could not be fully explained by variation in incidence nor in breast cancer detection rates. It suggests the potential for wide discrepancies in management of DCIS resulting in overtreatment of indolent DCIS or undertreatment of potentially curable disease. Comprehensive cancer registration is needed to monitor DCIS detection. Efforts to understand discrepancies and standardise management may improve care.

KW - Aged

KW - Breast Neoplasms

KW - Carcinoma, Ductal, Breast

KW - Carcinoma, Intraductal, Noninfiltrating

KW - Data Collection

KW - Early Detection of Cancer

KW - Europe

KW - Female

KW - Humans

KW - Mammography

KW - Middle Aged

KW - United States

U2 - 10.1016/j.ejca.2013.08.013

DO - 10.1016/j.ejca.2013.08.013

M3 - Journal article

VL - 50

SP - 185

EP - 192

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

IS - 1

ER -

ID: 135653830