Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes: Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’

Research output: Contribution to journalJournal articlepeer-review

Standard

Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes : Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’. / Holmes-Truscott, Elizabeth; Holloway, Edith E; Husin, Hanafi M; Furler, John; Hagger, Virginia; Skinner, Timothy C; Speight, Jane.

In: BMJ Open, Vol. 12, e051524, 02.2022.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Holmes-Truscott, E, Holloway, EE, Husin, HM, Furler, J, Hagger, V, Skinner, TC & Speight, J 2022, 'Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes: Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’', BMJ Open, vol. 12, e051524. https://doi.org/10.1136/bmjopen-2021-051524

APA

Holmes-Truscott, E., Holloway, E. E., Husin, H. M., Furler, J., Hagger, V., Skinner, T. C., & Speight, J. (2022). Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes: Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’. BMJ Open, 12, [e051524]. https://doi.org/10.1136/bmjopen-2021-051524

Vancouver

Holmes-Truscott E, Holloway EE, Husin HM, Furler J, Hagger V, Skinner TC et al. Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes: Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’. BMJ Open. 2022 Feb;12. e051524. https://doi.org/10.1136/bmjopen-2021-051524

Author

Holmes-Truscott, Elizabeth ; Holloway, Edith E ; Husin, Hanafi M ; Furler, John ; Hagger, Virginia ; Skinner, Timothy C ; Speight, Jane. / Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes : Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’. In: BMJ Open. 2022 ; Vol. 12.

Bibtex

@article{5ed6df59143f4ecbb9e477acca22def7,
title = "Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes: Study protocol for a two-armed randomised controlled trial of {\textquoteleft}Is insulin right for me?{\textquoteright}",
abstract = "Introduction Psychological barriers to insulin therapy are associated with the delay of clinically indicated treatment intensification for people with type 2 diabetes (T2D), yet few evidence-based interventions exist to address these barriers. We describe the protocol for a randomised controlled trial (RCT) examining the efficacy of a novel, theoretically grounded, psychoeducational, web-based resource designed to reduce psychological barriers to insulin among adults with non-insulin treated T2D: {\textquoteleft}Is insulin right for me?{\textquoteright}.Methods and analysis Double-blind, parallel group RCT. A target sample of N=392 participants (n=196/arm) will be randomised (1:1) to {\textquoteleft}Is insulin right for me?{\textquoteright} (intervention) or widely available online resources (control). Eligible participants include adults (18–75 years), residing in Australia, currently taking oral hypoglycaemic agents to manage T2D. They will be primarily recruited via invitations and reminders from the national diabetes registry (from a purposefully selected sample of N≥12 000). Exclusion criteria: experience of self-administered injectable; previously enrolled in pilot RCT; {\textquoteleft}very willing{\textquoteright} to start insulin as baseline. Outcomes will be assessed via online survey at 2 weeks and 6 months. Primary outcome between-group: difference in mean negative Insulin Treatment Appraisal Scores (ITAS negative) at 2-week and 6-month follow-up. Secondary outcomes: between-group differences in mean positive insulin appraisals (ITAS positive) and percentage difference in intention to commence insulin at follow-up time points. All data analyses will be conducted according to the intention-to-treat principle.Ethics and dissemination Deakin University Human Research Ethics Committee (2020–073). Dissemination via peer-reviewed journals, conferences and a plain-language summary.Trial registration number ACTRN12621000191897; Australian and New Zealand Clinical Trials Registry.",
keywords = "Faculty of Social Sciences",
author = "Elizabeth Holmes-Truscott and Holloway, {Edith E} and Husin, {Hanafi M} and John Furler and Virginia Hagger and Skinner, {Timothy C} and Jane Speight",
year = "2022",
month = feb,
doi = "10.1136/bmjopen-2021-051524",
language = "English",
volume = "12",
journal = "BMJ Open",
issn = "2044-6055",
publisher = "BMJ Publishing Group",

}

RIS

TY - JOUR

T1 - Web-based intervention to reduce psychological barriers to insulin therapy among adults with non-insulin-treated type 2 diabetes

T2 - Study protocol for a two-armed randomised controlled trial of ‘Is insulin right for me?’

AU - Holmes-Truscott, Elizabeth

AU - Holloway, Edith E

AU - Husin, Hanafi M

AU - Furler, John

AU - Hagger, Virginia

AU - Skinner, Timothy C

AU - Speight, Jane

PY - 2022/2

Y1 - 2022/2

N2 - Introduction Psychological barriers to insulin therapy are associated with the delay of clinically indicated treatment intensification for people with type 2 diabetes (T2D), yet few evidence-based interventions exist to address these barriers. We describe the protocol for a randomised controlled trial (RCT) examining the efficacy of a novel, theoretically grounded, psychoeducational, web-based resource designed to reduce psychological barriers to insulin among adults with non-insulin treated T2D: ‘Is insulin right for me?’.Methods and analysis Double-blind, parallel group RCT. A target sample of N=392 participants (n=196/arm) will be randomised (1:1) to ‘Is insulin right for me?’ (intervention) or widely available online resources (control). Eligible participants include adults (18–75 years), residing in Australia, currently taking oral hypoglycaemic agents to manage T2D. They will be primarily recruited via invitations and reminders from the national diabetes registry (from a purposefully selected sample of N≥12 000). Exclusion criteria: experience of self-administered injectable; previously enrolled in pilot RCT; ‘very willing’ to start insulin as baseline. Outcomes will be assessed via online survey at 2 weeks and 6 months. Primary outcome between-group: difference in mean negative Insulin Treatment Appraisal Scores (ITAS negative) at 2-week and 6-month follow-up. Secondary outcomes: between-group differences in mean positive insulin appraisals (ITAS positive) and percentage difference in intention to commence insulin at follow-up time points. All data analyses will be conducted according to the intention-to-treat principle.Ethics and dissemination Deakin University Human Research Ethics Committee (2020–073). Dissemination via peer-reviewed journals, conferences and a plain-language summary.Trial registration number ACTRN12621000191897; Australian and New Zealand Clinical Trials Registry.

AB - Introduction Psychological barriers to insulin therapy are associated with the delay of clinically indicated treatment intensification for people with type 2 diabetes (T2D), yet few evidence-based interventions exist to address these barriers. We describe the protocol for a randomised controlled trial (RCT) examining the efficacy of a novel, theoretically grounded, psychoeducational, web-based resource designed to reduce psychological barriers to insulin among adults with non-insulin treated T2D: ‘Is insulin right for me?’.Methods and analysis Double-blind, parallel group RCT. A target sample of N=392 participants (n=196/arm) will be randomised (1:1) to ‘Is insulin right for me?’ (intervention) or widely available online resources (control). Eligible participants include adults (18–75 years), residing in Australia, currently taking oral hypoglycaemic agents to manage T2D. They will be primarily recruited via invitations and reminders from the national diabetes registry (from a purposefully selected sample of N≥12 000). Exclusion criteria: experience of self-administered injectable; previously enrolled in pilot RCT; ‘very willing’ to start insulin as baseline. Outcomes will be assessed via online survey at 2 weeks and 6 months. Primary outcome between-group: difference in mean negative Insulin Treatment Appraisal Scores (ITAS negative) at 2-week and 6-month follow-up. Secondary outcomes: between-group differences in mean positive insulin appraisals (ITAS positive) and percentage difference in intention to commence insulin at follow-up time points. All data analyses will be conducted according to the intention-to-treat principle.Ethics and dissemination Deakin University Human Research Ethics Committee (2020–073). Dissemination via peer-reviewed journals, conferences and a plain-language summary.Trial registration number ACTRN12621000191897; Australian and New Zealand Clinical Trials Registry.

KW - Faculty of Social Sciences

U2 - 10.1136/bmjopen-2021-051524

DO - 10.1136/bmjopen-2021-051524

M3 - Journal article

C2 - 35190420

VL - 12

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

M1 - e051524

ER -

ID: 298086513