Rudi GJ Westendorp

Rudi GJ Westendorp

Professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. Published

    HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

    Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J., Howard, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., van der A, D. L., Forouhi, N. G., Onland-Moret, N. C., van der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., de Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, Rudi GJ, de Borst, G. J., de Jong, P. A., Algra, A., Spiering, W., Maitland-van der Zee, A. H., Klungel, O. H., de Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., van der Harst, P., Brunner, E. J., Tybjærg-Hansen, Anne, Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N., 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Cellular senescence and chronological age in various human tissues: A systematic review and meta-analysis

    Tuttle, C. S. L., Waaijer, M. E. C., Slee-Valentijn, M. S., Stijnen, T., Westendorp, Rudi GJ & Maier, A. B., 2020, In: Aging Cell. 19, 2, 11 p., e13083.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?

    Waaijer, M. E. C., Westendorp, Rudi GJ, Goldeck, D., Gunn, D. A., Pawelec, G., Stijntjes, M., Slagboom, P. E. & Maier, A. B., Jan 2017, In: Experimental Gerontology. 87, Part B, p. 175–181 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age

    Waaijer, M. E. C., Croco, E., Westendorp, Rudi GJ, Slagboom, P. E., Sedivy, J. M., Lorenzini, A. & Maier, A. B., 30 Jan 2016, In: Aging. 8, 1, p. 147-155 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Do senescence markers correlate in vitro and in situ within individual human donors?

    Waaijer, M. E. C., Gunn, D. A., van Heemst, D., Slagboom, P. E., Sedivy, J. M., Dirks, R. W., Tanke, H. J., Westendorp, Rudi GJ & Maier, A. B., 2018, In: Aging. 10, 2, p. 278-289 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Are skin senescence and immunosenescence linked within individuals?

    Waaijer, M. E. C., Goldeck, D., Gunn, D. A., van Heemst, D., Westendorp, Rudi GJ, Pawelec, G. & Maier, A. B., 2019, In: Aging Cell. 18, 4, 5 p., e12956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age

    Waaijer, M. E. C., Gunn, D. A., Adams, P. D., Pawlikowski, J. S., Griffiths, C. E. M., van Heemst, D., Slagboom, P. E., Westendorp, Rudi GJ & Maier, A. B., Aug 2016, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 71, 8, p. 1022-1028 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells

    Weilner, S., Schraml, E., Wieser, M., Messner, P., Schneider, K., Wassermann, K., Micutkova, L., Fortschegger, K., Maier, A. B., Westendorp, Rudi GJ, Resch, H., Wolbank, S., Redl, H., Jansen-Dürr, P., Pietschmann, P., Grillari-Voglauer, R. & Grillari, J., Aug 2016, In: Aging Cell. 15, 4, p. 744–754 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Corporate culture: research can benefit

    Westendorp, Rudi GJ & Wewer, Ulla M., 2017, In: Nature. 542, 7641, 1 p., 295.

    Research output: Contribution to journalJournal articleCommunication

  10. Published

    Bedside manners: How to deal with delirium

    Westendorp, Rudi GJ, Sep 2017, In: Cleveland Clinic Journal of Medicine. 84, 9, p. 699-700 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  11. Published

    Gaan we luisteren of meten?

    Westendorp, Rudi GJ & Kusumastuti, Sasmita, 18 Nov 2019, In: Nederlands Tijdschrift voor Geneeskunde. 163, D4473.

    Research output: Contribution to journalComment/debateResearch

  12. Published

    High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk

    Wijsman, L. W., de Craen, A. J., Trompet, S., Sabayan, B., Muller, M., Stott, D. J., Ford, I., Welsh, P., Westendorp, Rudi GJ, Jukema, J. W., Sattar, N. & Mooijaart, S. P., Sep 2016, In: European Journal of Preventive Cardiology. 23, 13, p. 1383-1392 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Blood Pressure Lowering Medication, Visit-to-Visit Blood Pressure Variability, and Cognitive Function in Old Age

    Wijsman, L. W., de Craen, A. J. M., Muller, M., Sabayan, B., Stott, D., Ford, I., Trompet, S., Jukema, J. W., Westendorp, Rudi GJ & Mooijaart, S. P., Mar 2016, In: American Journal of Hypertension. 29, 3, p. 311-318 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history

    Wijsman, L. W., Muller, M., de Craen, A. J. .. M., Jukema, J. W., Westendorp, Rudi GJ & Mooijaart, S. P., 2018, In: Journal of Hypertension. 36, 4, p. 773–778 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms

    Wildisen, L., Del Giovane, C., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Collet, T., Cappola, A. R., Asvold, B. O., Bakker, S. J. L., Yeap, B. B., Almeida, O. P., Ceresini, G., Dullaart, R. P. F., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, Rudi GJ, Gussekloo, J., Kloppel, S., Aujesky, D., Bauer, D., Peeters, R., Feller, M. & Rodondi, N., 2020, In: Scientific Reports. 10, 1, 12 p., 19111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies

    Wildisen, L., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Cappola, A. R., Åsvold, B. O., Bakker, S. J. L., Ceresini, G., Dullaart, R., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, Rudi GJ, Gussekloo, J., Peeters, R. P., Kloeppel, S., Aujesky, D., Bauer, D. C., Rodondi, N., Del Giovane, C. & Feller, M., 2019, In: BMJ Open. 9, 7, 4 p., 029716.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism An Ancillary Study of a Randomized Clinical Trial

    Wildisen, L., Feller, M., Del Giovane, C., Moutzouri, E., Du Puy, R. S., Mooijaart, S. P., Collet, T., Poortvliet, R. K. E., Kearney, P., Quinn, T. J., Kloppel, S., Bauer, D. C., Peeters, R. P., Westendorp, Rudi GJ, Aujesky, D., Gussekloo, J. & Rodondi, N., 2021, In: JAMA network open. 4, 2, 12 p., 2036645.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data

    Thyroid Studies Collaboration, T. S. C., 2018, In: The Journal of clinical endocrinology and metabolism. 103, 10, p. 3658-3667 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. E-pub ahead of print

    Personalised need of care in an ageing society: the making of a prediction tool based on register data

    Wright, M. N., Kusumastuti, Sasmita, Mortensen, Laust Hvas, Westendorp, Rudi GJ & Gerds, Thomas Alexander, 2021, (E-pub ahead of print) In: Journal of the Royal Statistical Society, Series A (Statistics in Society).

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Onset of Workplace Bullying and Risk of Weight Gain: A Multicohort Longitudinal Study

    Xu, T., Magnusson Hanson, L. L., Clark, A. J., Ersbøll, A. K., Westerlund, H., Madsen, I. E. H., Rugulies, Reiner Ernst, Pentti, J., Stenholm, S., Vahtera, J., Sørensen, Jeppe Karl, Nordentoft, M., Westendorp, Rudi GJ, Hansen, Åse Marie, Oksanen, T., Virtanen, M., Kivimäki, M. & Rod, Naja Hulvej, 2020, In: Obesity. 28, 11, p. 2216-2223 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials

    Zijlstra, L. E., Jukema, J. W., Westendorp, Rudi GJ, Du Puy, R. S., Poortvliet, R. K. E., Kearney, P. M., O'Keeffe, L., Dekkers, O. M., Blum, M. R., Rodondi, N., Collet, T., Quinn, T. J., Sattar, N., Stott, D. J., Trompet, S., den Elzen, W. P. J., Gussekloo, J. & Mooijaart, S. P., 2021, In: Frontiers in Endocrinology. 12, 8 p., 674841.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

    Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone

    Zutinic, A., Pijl, H., Ballieux, B. E., Roelfsema, F., Westendorp, Rudi GJ, Blauw, G. J. & van Heemst, D., 1 Jul 2020, In: The Journal of clinical endocrinology and metabolism. 105, 7, p. e2572–e2580 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial

    de Montmollin, M., Feller, M., Beglinger, S., McConnachie, A., Aujesky, D., Collet, T., Ford, I., Gussekloo, J., Kearney, P. M., McCarthy, V. J. C., Mooijaart, S., Poortvliet, R. K. E., Quinn, T., Stott, D. J., Watt, Torquil, Westendorp, Rudi GJ, Rodondi, N. & Bauer, D. C., 2 Jun 2020, In: Annals of Internal Medicine. 172, 11, p. 709-716 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey

    den Elzen, W. P. J., Lefèbre-van de Fliert, A. A., Virgini, V., Mooijaart, S. P., Frey, P., Kearney, P. M., Kerse, N., Mallen, C. D., McCarthy, V. J. C., Muth, C., Rosemann, T., Russell, A., Schers, H., Stott, D. J., de Waal, M. W. M., Warner, A., Westendorp, Rudi GJ, Rodondi, N. & Gussekloo, J., Feb 2015, In: British Journal of General Practice. 65, 631, p. e121-132 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Disentangling the effects of circulating IGF-1, glucose, and cortisol on features of perceived age

    van Drielen, K., Gunn, D. A., Noordam, R., Griffiths, C. E. M., Westendorp, Rudi GJ, de Craen, A. J. M. & van Heemst, D., Jun 2015, In: Age (Omaha). 37, 34, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effect of APOE ε4 allele on survival and fertility in an adverse environment

    van Exel, E., Koopman, J. J. E., Bodegom, D. V., Meij, J. J., Knijff, P. D., Ziem, J. B., Finch, C. E. & Westendorp, Rudi GJ, 6 Jul 2017, In: PLOS ONE. 12, 7, p. 1-13 13 p., e0179497.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effects of intranasal insulin application on the hypothalamic BOLD response to glucose ingestion

    van Opstal, A. M., Akintola, A. A., Elst, M. V. D., Westendorp, Rudi GJ, Pijl, H., van Heemst, D. & van der Grond, J., 17 Oct 2017, In: Scientific Reports. 7, p. 1-7 7 p., 13327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study

    van Vliet, N. A., Noordam, R., van Klinken, J. B., Westendorp, Rudi GJ, Bassett, J. D., Williams, G. R. & van Heemst, D., 2018, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33, 7, p. 1318-1325 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Thyroid status and mortality in nonagenarians from long-lived families and the general population

    van Vliet, N. A., van der Spoel, E., Beekman, M., Slagboom, P. E., Blauw, G. J., Gussekloo, J., Westendorp, Rudi GJ & van Heemst, D., Oct 2017, In: Aging. 9, 10, p. 2223—2234 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Early and extraordinary peaks in physical performance come with a longevity cost

    van de Vijver, P. L., van Bodegom, D. & Westendorp, Rudi GJ, 19 Aug 2016, In: Aging. 8, 8, p. 1822-1829 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

    van der Spoel, E., Rozing, M. P., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., de Craen, A. J. M., Westendorp, Rudi GJ & van Heemst, D., 12 Nov 2015, In: Aging. 7, 11, p. 956–963 8 p., PMC4694065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

    van der Spoel, E., Roelfsema, F., Akintola, A. A., Jansen, S. W., Slagboom, P. E., Westendorp, Rudi GJ, Blauw, G. J., Pijl, H. & van Heemst, D., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. e1201–e1214 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Familial Longevity Is Not Associated with Major Differences in the Hypothalamic–Pituitary–Gonadal Axis in Healthy Middle-Aged Men

    van der Spoel, E., Roelfsema, F., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Blauw, G. J., Slagboom, P. E., Westendorp, Rudi GJ, Piji, H. & van Heemst, D., 9 Nov 2016, In: Frontiers in Endocrinology. 7, p. 1-7 7 p., 143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity

    van der Spoel, E., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Slagboom, P. E., Blauw, G. J., Westendorp, Rudi GJ, Pijl, H., Roelfsema, F. & van Heemst, D., Dec 2016, In: Aging Cell. 15, 6, p. 1126–1131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Thyroid Function Within the Normal Range and Risk of Coronary Heart Disease: An Individual Participant Data Analysis of 14 Cohorts

    Åsvold, B. O., Vatten, L. J., Bjøro, T., Bauer, D. C., Bremner, A., Cappola, A. R., Ceresini, G., den Elzen, W. P. J., Ferrucci, L., Franco, O. H., Franklyn, J. A., Gussekloo, J., Iervasi, G., Imaizumi, M., Kearney, P. M., Khaw, K., Maciel, R. M. B., Newman, A. B., Peeters, R. P., Psaty, B. M., Razvi, S., Sgarbi, J. A., Stott, D. J., Trompet, S., Vanderpump, M. P. J., Völzke, H., Walsh, J. P., Westendorp, Rudi GJ, Rodondi, N. & Thyroid Studies Collaboration, T. S. C., Jun 2015, In: J A M A Internal Medicine. 175, 6, p. 1037-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 Next

ID: 129476659