Research areas

  1. Published

    Phorbol Rearrangements

    Zimmermann, T., Franzyk, Henrik & Christensen, Søren Brøgger, 28 Sep 2018, In: Journal of Natural Products. 81, 9, p. 2134-2137 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

    Zimmermann, T., Christensen, Søren Brøgger & Franzyk, Henrik, 15 Jun 2018, In: Molecules. 23, 6, 13 p., 1463.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+-Transport ATPase (SPCA1a)

    Jialin, C., de Raeymaecker, J., Hovgaard, J. B., Smaardijk, S., Vandecaetsbeek, I., Wuytack, F., Møller, J. V., Eggermont, J., de Meyer, M., Christensen, Søren Brøgger & Vangheluwe, P., 2017, In: Journal of Biological Chemistry. 292, 17, p. 6938-6951 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs

    Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, C. B., Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Lithostratigraphy, geology and geochemisttry of the volcanic rocks of the Vaigat Formation on Disko and Nuussuaq, Paleocene of West Greenland

    Pedersen, Asger Ken, Larsen, L. M. & Pedersen, G. K., 2017, Copenhagen: The Geological Survey of Denmark and Greenland. 244 p. (Geological Survey of Denmark and Greenland (GEUS) Bulletin, Vol. 39).

    Research output: Book/ReportBookpeer-review

  6. Published

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

    Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In: European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Basic characteristics and kinetics of degradation in aqueous buffer of selected diclofenac prodrugs intended for joint injection

    Mertz, Nina, Larsen, Susan Weng & Larsen, C. S., 6 Apr 2016. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  8. Published

    Cytochrome P450 Mediated Drug Metabolism

    Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    The potential of protein-nanomaterial interaction for advanced drug delivery

    Peng, Q. & Mu, Huiling, 23 Jan 2016, In: Journal of Controlled Release. 225, p. 121-132 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

    Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development.

    Doan, T. Q. N. & Christensen, Søren Brøgger, Oct 2015, In: Current Pharmaceutical Design. 21, 38, p. 5505-5517 13 p.

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score

    Laustsen, A. H. & Lohse, B., 15 Sep 2015, In: Toxicon. 104, p. 43-45 3 p.

    Research output: Contribution to journalLetterpeer-review

  13. Published

    Noter til Organisk Kemi for Biovidenskab: Organisk og bioorganisk kemi 2015

    Nielsen, J., 9 Feb 2015, 25 p.

    Research output: Other contributionEducation

  14. Published

    The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice

    Diep, T. A., Golbas, G. & Hansen, Harald S., 28 Jun 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  15. Published

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking

    Hauser, Alexander Sebastian, 1 Aug 2014, In: Medicinal Chemistry Research. 23, 8, p. 3861 3875 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices

    Bak, S. A., Hansen, M., Krogh, K. A., Brandt, A., Halling-Sørensen, B. & Björklund, E., 25 Feb 2013, In: International Journal of Environmental Analytical Chemistry. 93, 14, p. 1500-1512

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Altered anziety/depression-like behaviours in mice deficient in tetrahydrobiopterin

    Nasser, A., Birk Møller, L. & Andreasen T., Jesper, 13 Jan 2013.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  18. Published

    Organ culture of C57BL/6 mouse arteries with LPS as an in vitro model of vascular inflammation

    Outzen, E. M., Mehryar, R., Boonen, H. C. M., Nielsen, A. S. & Sheykhzade, Majid, 28 Aug 2013. 1 p.

    Research output: Contribution to conferencePosterResearch

  19. Published

    Lactate dehydrogenase assay for assessment of polycation cytotoxicity

    Parhamifar, L., Andersen, H. & Moghimi, S. M., 2013, Nanotechnology for Nucleic Acid Delivery. Vol. 948. p. 13-22 10 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  20. Exploring the solid-form landscape of pharmaceutical hydrates: transformation pathways of the sodium naproxen anhydrate-hydrate system

    Raijada, D. K., Bond, A., Larsen, F. H., Cornett, C., Qu, H. & Rantanen, J., Jan 2013, In: Pharmaceutical Research. 30, 1, p. 280-289 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Exploring the solid-form landscape of pharmaceutical hydrates: transformation pathways of the sodium naproxen anhydrate-hydrate system

    Raijada, D. K., Bond, A., Larsen, F. H., Cornett, Claus, Qu, H. & Rantanen, Jukka, 2013, In: Pharmaceutical Research. 30, 1, p. 280-289 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Pollution Pathways of Pharmaceutical Residues in the Aquatic Environment on the Island of Mallorca, Spain

    Rodríguez-Navas, C., Björklund, E., Bak, S. A., Hansen, M., Krogh, K. A., Maya, F., Forteza, R. & Cerdà, V., 2013, In: Archives of Environmental Contamination and Toxicology. 61, 1, p. 56-66

    Research output: Contribution to journalJournal articlepeer-review

  23. Liposomal temocene (m-THPPo) photodynamic treatment induces cell death by mitochondria-independent apoptosis

    Soriano, J., Garcia-Diaz, M., Mora, M., Sagristá, M. L., Nonell, S., Villanueva, A., Stockert, J. C. & Cañete, M., 28 May 2013, In: BBA General Subjects. 1830, 10, p. 4611-4620 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Pattern-oriented Agent-based Monte Carlo simulation of Cellular Redox Environment

    Tang, J., Holcombe, M. & Boonen, H. C. M., 28 Aug 2013. 1 p.

    Research output: Contribution to conferencePosterResearch

  25. Published

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat

    Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT)

    Aksu, B., De Beer, T., Folestad, S., Ketolainen, J., Lindén, H., Lopes, J. A., de Matas, M., Oostra, W., Rantanen, Jukka & Weimer, M., 29 Sep 2012, In: European Journal of Pharmaceutical Sciences. 47, 2, p. 402-405 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journalJournal article

  28. Published

    Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane exctraction

    Balchen, M., Lund, H., Reubsaet, L. & Pedersen-Bjergaard, Stig, 2012, In: Analytica Chimica Acta. 716, p. 16-23

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    In vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against Taenia Solium cysts

    Cederberg, S., Sikasunge, C. S., Andersson, Åsa & Johansen, M. V., 2012, In: Journal of Parasitology Research. 2012, 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Role of excipients on solid-state properties of piroxicam during processing

    Christensen, N. P. A., Cornett, Claus & Rantanen, Jukka, 2012, In: Journal of Pharmaceutical Sciences. 101, 3, p. 1202-1211

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Drugs for the neglected disease malaria based on natural products

    Christensen, Søren Brøgger & Bygbjerg, Ib Christian, 2012, Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. Tringali, C. (ed.). 2 ed. Boca Raton: CRC Press, p. 525-550

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  32. Published

    Concise synthesis of new bridged-nicotine analogues

    Crestey, F., Hooyberghs, G. & Kristensen, Jesper Langgaard, 4 Feb 2012, In: Tetrahedron. 68, 5, p. 1417-1421

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

    Devraj, R., Williams, H. D., Warren, D. B., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In: International Journal of Pharmaceutics. 441, 1-2, p. 323-333

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Multidisciplinary management of metastatic renal cell carcinoma in the era of targeted therapies

    Escudier, B., Osanto, S., Ljungberg, B., Porta, C., Wagstaff, J., Mulders, P., Gore, M., Bex, A., Bellmunt, J., Bracarda, S., Franklin, A., Honoré, P. G. H., Ravaud, A., Stein, J. V., Aziz, Z. & Akaza, H., 2012, In: Cancer Treatment Reviews. 38, 2, p. 127-132 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    License to kill: formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems

    Foged, Camilla, Hansen, J. & Agger, E. M., 2012, In: European Journal of Pharmaceutical Sciences. 45, 4, p. 482-491

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Estimating intestinal absorption of inorganic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection

    Gammelgaard, Bente, Rasmussen, L. H., Gabel-Jensen, C. & Steffansen, B., 2012, In: Biological Trace Element Research. 145, 2, p. 248-256

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS

    Gammelgaard, Bente, Stürup, Stefan & Christensen, M. V., 2012, In: Metallomics. 4, 2, p. 149-155

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Volatile organic compounds in landfill ordorant emissions on the island of Mallorca

    González, C. R., Björklund, E., Forteza, R. & Cerdà, V., 2012, In: International Journal of Environmental Analytical Chemistry. 92, 12, p. 1-16, iFirst

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Introduction to pharmaceutical chemical analysis

    Hansen, S. H., Pedersen-Bjergaard, Stig & Rasmussen, K. E., 2012, Chichester: Wiley. 477 p.

    Research output: Book/ReportBookpeer-review

  40. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains

    Haq, S. R., Chi, C. N., Bach, Anders, Dogan, J., Engström, Å., Hultqvist, G., Karlsson, O. A., Lundström, P., Montemiglio, L. C., Strømgaard, Kristian, Gianni, S. & Jemth, P., Jan 2012, In: Journal of the American Chemical Society. 134, 1, p. 599-605

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    An electrochemical approach to protein adsorption at charged interfaces

    Hartvig, R. A., 2012, København: Det Farmaceutiske Fakultet. 127 p.

    Research output: Book/ReportPh.D. thesis

  42. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Forced degradation of therapeutic proteins

    Hawe, A., Wiggenhorn, M., van de Weert, Marco, Garbe, J. H. O., Mahler, H. & Jiskoot, W., 2012, In: Journal of Pharmaceutical Sciences. 101, 3, p. 895-913

    Research output: Contribution to journalReviewpeer-review

  44. Published

    Evaluation of the antibacterial activity of Chilean plants traditionally used for wound healing therapy against multidrug-resistant Staphylococcus aureus

    Holler, J. G., Søndergaard, K., Slotved, H., Gúzman, A. & Mølgaard, Per, Jan 2012, In: Planta Medica. 78, 2, p. 200-205

    Research output: Contribution to journalLetterpeer-review

  45. Published

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

    Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In: European Journal of Pharmaceutical Sciences. 47, p. 347-351

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA

    Jensen, D. M. K., Jensen, L. B., Koocheki, S., Cun, D., Nielsen, Hanne Mørck, Foged, Camilla & Bengtson, L., 2012, In: Journal of Controlled Release. 157, 1, p. 141-148

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression

    Jensen, L. B., Griger, J., Naeye, B., Varkouhi, A. K., Raemdonck, K., Schiffelers, R., Lammers, T., Storm, G., Smedt, S. C. D., Sproat, B. S., Nielsen, Hanne Mørck & Foged, Camilla, 2012, In: Pharmaceutical Research. 29, p. 669-682

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake

    Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In: Langmuir. 28, 11, p. 5167-5175

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Quality assessment of Tulbaghia rhizomes

    Jäger, A. & Stafford, G. I., Sep 2012, In: South African Journal of Botany. 82, p. 92-98 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Tool boxes for an integrated ecological and environmental management

    Jørgensen, S. E. & Nielsen, S. N., 2012, In: Ecological Indicators. 21, p. 104-109

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators

    Kaae, B. H., Harpsøe, Kasper, Kvist, T., Mathiesen, Jesper M., Mølck, C., Gloriam, David E., Jimenez, H. N., Uberti, M. A., Nielsen, S. M., Nielsen, Birgitte, Bräuner, Hans, Sauerberg, P., Clausen, Rasmus Prætorius & Madsen, Ulf, 2012, In: ChemMedChem. 7, 3, p. 440-451

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    How to engage experienced medicine users at the counter for a pharmacy-based asthma inhaler service

    Kaae, Susanne & Nørgaard, Lotte Stig, 2012, In: International Journal of Pharmacy Practice. 20, p. 99-106

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

    Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: International Journal of Pharmaceutics. 428, 1-2, p. 171-177

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction

    Koradia, V. S., Tenho, M., Diego, H. L. D., Ringkjøbing-Elma, M., Møller-Sonnergaard, Jørn, Salonen, J., Lehto, V. & Rantanen, Jukka, 2012, In: Pharmaceutical Research. 29, 1, p. 134-144

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In: Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil

    Kristensen, J. B., Jørgensen, H. & Mu, Huiling, 2012, In: European Journal of Lipid Science and Technology. 114, 2, p. 146-152

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors

    Kristensen, L. H., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 168 p.

    Research output: Book/ReportPh.D. thesis

  58. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, P., Kastrup, Jette Sandholm Jensen, Helin, K., Olsen, L. & Gajhede, Michael, Jun 2012, In: F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    Internal correction of spectral interferences and mass bias for selenium metabolism studies using enriched stabel isotopes in combination with multiple linear regression

    Lunøe, K., Martinez-Sierra, J. G., Gammelgaard, Bente & Alonso, J. I. G., 2012, In: Analytical and Bioanalytical Chemistry. 402, 9, p. 2749-2763

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    Modelling the carbon cycle of Siena province (Tuscany, central Italy)

    Marchi, M., Jørgensen, S. E., Pulselli, F. M., Marchettini, N. & Bastianoni, S., 2012, In: Ecological Modelling. 225, p. 40-60

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo

    Mullertz, Anette , Fatouros, D. G., Smith, J. R., Vertzoni, M. & Reppas, C., 2012, In: Molecular Pharmaceutics. 9, 2, p. 237-247

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In: Analytical and Bioanalytical Chemistry. 402, p. 2131-2139

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABAA receptors

    Nilsson, J., Nielsen, E. Ø., Liljefors, T., Nielsen, M. P. C. & Sterner, O., Feb 2012, In: Bioorganic Chemistry. 40, p. 125-130

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Role of Cu2+ in oligomerization and aggregation of alzheimer's amyloid-β peptides

    Pedersen, J. T., 2012, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet. 85 p.

    Research output: Book/ReportPh.D. thesis

  68. Published

    Behaviour of HPMC compacts investigated using UV-imaging

    Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    A robust force field based method for calculating conformational energies of charged drug-like molecules

    Pøhlsgaard, J., Harpsøe, Kasper, Jørgensen, Flemming Steen & Olsen, L., 2012, In: Journal of Chemical Information and Modeling. 52, 2, p. 409-419

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation

    Rand, Kasper Dyrberg, Pringle, S. D., Morris, M. & Brown, J. M., 2012, In: Analytical Chemistry. 84, 4, p. 1931-1940

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: Unique role of halogen bonding revealed

    Rohde, L. A. H., Ahring, P. K., Jensen, M. L., Nielsen, E. Ø., Peters, D., Helgstrand, C., Krintel, C., Harpsøe, Kasper, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Balle, T., 3 Feb 2012, In: The Journal of Biological Chemistry. 287, 6, p. 4248-4259

    Research output: Contribution to journalJournal articlepeer-review

  72. Published

    Comment on "Binding free energies of inhibitors to iron porphyrin complex as a model for cytochrome P450"

    Rydberg, P., Apr 2012, In: Biopolymers. 97, 4, p. 250-251

    Research output: Contribution to journalComment/debatepeer-review

  73. Published

    Ligand-based site of metabolism prediction for cytochrome P450 2D6

    Rydberg, P. & Olsen, L., 12 Jan 2012, In: A C S Medicinal Chemistry Letters. 3, 1, p. 69-73

    Research output: Contribution to journalLetterpeer-review

  74. Published

    Genetic fuzzy system modeling and simulation of vascular behaviour

    Tang, J. & Boonen, H. C. M., 13 Jun 2012. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  75. Published

    In vitro release from oil injectabels for intra-articular administration: importance of interfacial area, diffusivity and partitioning

    Thing, M. A., Larsen, C. S., Østergaard, Jesper, Jensen, H. & Larsen, Susan Weng, 2012, In: European Journal of Pharmaceutical Sciences. 45, 3, p. 351-357

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems

    Thomas, N., Mullertz, Anette , Graf, A. & Rades, T., 2012, In: Journal of Pharmaceutical Sciences. 101, 5, p. 1721-1731

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Biased agonism of the calcium-sensing receptor

    Thomsen, A. R. B., Hvidtfeldt, M. & Bräuner, Hans, Feb 2012, In: Cell Calcium. 51, 2, p. 107-116

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine

    Thunig, J., Flø, L., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2012, In: Rapid Communications in Massspectrometry. 26, 2, p. 133-140

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    A 3D-QSAR-driven approach to binding mode and affinity prediction

    Tosco, P. & Balle, T., 2012, In: Journal of Chemical Information and Modeling. 52, 2, p. 302-307

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Chemical composition of the essential oil from Microlicia graveolens growing wild in Minas Gerais

    Toudahl, A. B., Filho, S. A. V., Souza, G. H. B., Morais, L. D., dos Santos, O. D. H. & Jäger, A., May 2012, In: Revista Brasileira de Farmacognosia. 22, 3, p. 680-681

    Research output: Contribution to journalLetterpeer-review

  81. Published

    Assessing element-specific patterns of bioaccumulation across New England lakes

    Ward, D. M., Mayes, B., Stürup, Stefan, Folt, C. L. & Chen, C. Y., 2012, In: Science of the Total Environment. 421-422, 3-4, p. 230-237

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration

    Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In: Biomacromolecules. 13, p. 905-917

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Polymer-mediated anti-solvent crystallization of nitrendipine: Monodispersed spherical crystals and growth mechanism

    Xia, D., Ouyang, M., Wu, J., Jiang, Y., Piao, H., Sun, S., Zheng, L., Rantanen, Jukka, Cui, F. & Yang, Mingshi, 2012, In: Pharmaceutical Research. 29, p. 158-169

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers

    Xia, D., Wu, J., Cui, F., Qu, H., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 15 Aug 2012, In: European Journal of Pharmaceutical Sciences. 46, 5, p. 446-454 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition

    Yaghmur, Anan, Rappolt, M., Østergaard, Jesper, Larsen, C. S. & Larsen, Susan Weng, 2012, In: Langmuir. 28, 5, p. 2881-2889

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Self-assembled nanostructures of fully hydrated monoelaidin - Elaidic and monoelaidin - Oleic acid systems

    Yaghmur, Anan, Satori, B. & Rappolt, M., 2012, In: Langmuir. 28, p. 10105-10119

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells

    Yang, L., Fawcett, J. P., Østergaard, Jesper, Zhang, H. & Tucker, I. G., 2012, In: Molecular Pharmaceutics. 9, 1, p. 29-36

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis

    Ye, F., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 61, p. 176-183

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix

    Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    NMR spectroscopy for metabolic profiling of plant extracts

    Yilmaz, A., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 114 p.

    Research output: Book/ReportPh.D. thesis

  91. Published

    RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes

    Zaretzki, J., Rydberg, P., Bergeron, C., Bennett, K. P., Olsen, L. & Breneman, C. M., 2012, In: Journal of Chemical Information and Modeling. 52, 6, p. 1637-1659

    Research output: Contribution to journalJournal articlepeer-review

  92. Published

    Adverse drug reactions following immunization in Danish children: retrospective analysis of spontaneous reports submitted to the Danish Medicines Agency

    Aagaard, L., Hansen, E. W. & Hansen, E. H., 2011, Science against microbial pathogens: communicating current research and technical advances. Méndez-Vilas, A. (ed.). Badajoz: Formatex, Vol. 1. p. 407-413 (Microbiology series; No. 3).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  93. Published

    Adverse events following immunization in children: retrospective analysis of spontaneous reports over a decade

    Aagaard, L., Hansen, E. W. & Hansen, E. H., 2011, In: European Journal of Clinical Pharmacology. 67, 1, p. 283-288

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Characteristics of adverse drug reactions related to off-label prescribing in the Danish paediatric population

    Aagaard, L. & Hansen, E. H., 2011. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  95. Published

    1H NMR- and HPLC-based metabolomics combined with hyphenated HPLC-SPE-NMR methods for the investigation of herbal remedies and medicinal plants

    Agnolet, S., 2011, København: Det Farmaceutiske Fakultet.

    Research output: Book/ReportPh.D. thesis

  96. Published

    Biological targeting and innovative therapeutic interventions with phage-displayed peptides and structured nucleic acids (aptamers)

    Ahmadvand, D., Rahbarizadeh, F. & Moghimi, S. M., 2011, In: Current Opinion in Biotechnology. 22, 2, p. 832-838

    Research output: Contribution to journalJournal articlepeer-review

  97. Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

    Andersen, J., Stuhr-Hansen, N., Zachariassen, L., Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A., Bøgesø, K. P., Bang-Andersen, B., Kristensen, A. S. & Strømgaard, K., 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142

    Research output: Contribution to journalJournal articlepeer-review

  98. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

    Andersen, J., Stuhr-Hansen, N., Zachariassen, L., Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A. D., Bøgesø, K. P., Bang-Andersen, B., Kristensen, Anders Skov & Strømgaard, Kristian, 19 Jul 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142

    Research output: Contribution to journalJournal articlepeer-review

  99. Published

    Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline

    Andreasen T., Jesper, Henningsen, K., Bate, S., Christiansen, S. & Wiborg, O., 1 Aug 2011, In: Journal of Psychopharmacology. 25, 8, p. 1134-41 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Improving the stability of alpha-conotoxin AuIB through N-to-C cyclization: The effect of linker length on stability and activity at nicotinic acetylcholine receptors

    Armishaw, C. J., Jensen, Anders A., Balle, L. D., Scott, K. C. M., Sørensen, L. & Strømgaard, Kristian, 2011, In: Antioxidants & Redox Signaling. 14, 1, p. 65-76

    Research output: Contribution to journalJournal articlepeer-review

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