Research areas

  1. Published

    Clinical rationale for administering fentanyl to cancer pain patients: two Delphi surveys of pain management experts in Denmark

    Jacobsen, Ramune, Møldrup, C. & Christrup, Lona Louring, 2008, In: Journal of Opioid Management. 4, 6, p. 383-391

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Investigation of racemisation of the enantiomers of glitazone drug compounds at different pH using chiral HPLC and chiral CE

    Jamali, B., Bjørnsdottir, I., Nordfang, O. & Hansen, S. H., 2008, In: Journal of Pharmaceutical and Biomedical Analysis. 46, 1, p. 82-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lægemidler fra naturstoffer: fortid eller fremtid?

    Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Investigations of pathophysiology and pharmacology in experimental models of bladder overactivity

    Jensen, D. G., 2008, Det Farmaceutiske Fakultet. 70 p.

    Research output: Book/ReportPh.D. thesisResearch

  5. Published

    Anti-plasmodial activity of extracts of five species of Icelandic liverworts

    Jensen, J. S. R., Palsdottir, G. M., Omarsdottir, S., Olafsdottir, E. S. & Jaroszewski, J. W., 2008, In: Planta Medica. 74, 9, p. 976 (PA150)

    Research output: Contribution to journalConference abstract in journalResearch

  6. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin

    Jensen, L. B., Nielsen, Hanne Mørck & Foged, Camilla, 2008, In: Lægemiddelforskning. p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  7. Published

    Pharmacokinetic-Pharmacodynamic relationships of cognitive and psychomotor effects of intravenous buprenorphine infusion in human volunteers

    Jensen, M. L., Sjøgren, P., Upton, R. N., Foster, D. J. R., Bonde, P., Graae, C., Skram, U., Stevner, L. L. S. & Christrup, Lona Louring, 2008, In: Basic & Clinical Pharmacology & Toxicology. 103, 1, p. 94-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Bioassay-guided isolation of apigenin with GABA-benzodiazepine activity from Tanacetum parthenium

    Jäger, A. K., Krydsfeldt, K. & Rasmussen, H. B., 2008.

    Research output: Contribution to conferencePosterResearch

  9. Published

    Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution

    Jørgensen, A. D., Nøhr, J., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sigurskjold, B. W., Sauer, J., Svergun, D. I., Svensson, B. & Vestergaard, Bente, 2008, In: Journal of Biological Chemistry. 283, 21, p. 14772-14780

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Humid storage conditions increase the dissolution rate of diazepam from solid dispersions prepared by melt agglomeration

    Jørgensen, A. C. & Torstenson, A. S., 2008, In: Pharmaceutical Development and Technology. 13, 3, p. 187-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    New initiative for thematic issues: An invitation: Brief overview of the five "hot" themes in Ecological Modelliong

    Jørgensen, S. E., Grant, W. E., Legovic, T. & Nielsen, S. N., 2008, In: Ecological Modelling. p. 273-275

    Research output: Contribution to journalComment/debateResearch

  12. Published

    Har apotekerne tjek på inhalationen?

    Kaae, Susanne, Søndergaard, B. & Nørgaard, Lotte Stig, 2008, In: Lægemiddelforskning. p. 37-39

    Research output: Contribution to journalJournal articleCommunication

  13. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

    Kasper, C., Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In: FEBS Letters. 582, 29, p. 4089-4094

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Brug biblioteket - find informationen: kompendium i biblioteksvejledning og informationssøgning

    Kastrup, E. H., Kristiansen, D., Kaad, L. & Weile, Martin, 2008, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet.

    Research output: Book/ReportCompendium/lecture notesEducation

  15. Published

    Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4

    Kayser, O., Julsing, M. K., Vasilev, N. P., Schneidman-Duhovny, D., Koulman, A., Clarkson, C., Woerdenbag, H. J., Ionkova, I., Wolfson, H. J., Bos, R., Muntendam, R., Jaroszewski, J. W. & Quax, W. J., 2008, In: Planta Medica. 74, 9, p. 925 (SL74)

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    Establishing quantitative in-line analysis of multiple solid-state transformations during dehydration

    Kogermann, K., Aaltonen, J., Strachan, C. J., Pöllänen, K., Heinämäki, J., Yliruusi, J. & Rantanen, Jukka, 2008, In: Journal of Pharmaceutical Sciences. 97, 11, p. 4983-4999

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Synthesis of RHPS4 via an anionic ring closing cascade

    Kristensen, Jesper Langgaard, 2008, In: Tetrahedron Letters. 49, 15, p. 2351-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp

    Kristensen, O., Ross, B. & Gajhede, Michael, 2008, In: Journal of Molecular Biology. 375, 5, p. 1469-1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry

    Krogh, K. A., Björklund, B. E., Loeffler, D., Fink, G., Halling-Sørensen, B. & Ternes, T. A., 2008, In: Journal of Chromatography A. 1211, 1-2, p. 60-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Sorption and mobility of ivermectin in different soils

    Krogh, K. A., Søborg, T., Larsen, Birger Brodin & Halling-Sørensen, B., 2008, In: Journal of Environmental Quality. 37, 6, p. 2202-2211

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling

    Krzywkowski, K. M., Davies, P. A., Irving, A. J., Bräuner, Hans & Jensen, Anders A., 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 12, p. 1027-1040

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Bräuner, Hans & Jensen, Anders A., 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 2, p. 722-727

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Human 5-HT3 receptors: implications of genetic variations, chaperone proteins, and subunit concatenation on function and expression

    Krzywkowski, K. M., 2008, København: Det Farmaceutiske Fakultet. 100 p.

    Research output: Book/ReportPh.D. thesisResearch

  24. Published

    Flavylium salts as in vitro precursors of potent ligands to brain GABA-A receptors

    Kueny-Stotz, M., Chassaing, S., Brouillard, R., Nielsen, M. P. C. & Goeldner, M., 2008, In: Bioorganic & Medicinal Chemistry Letters. 18, 17, p. 4864-4867

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors

    Lager, E., Nilsson, J., Nielsen, E. Ø., Nielsen, M. P. C., Liljefors, T. & Sterner, O., 2008, In: Bioorganic & Medicinal Chemistry. 16, 14, p. 6936-6948

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Lipid-based formulations for danazol containing a digestible surfactant, labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis

    Larsen, A., Holm, R., Pedersen, M. L. & Mullertz, Anette , 2008, In: Pharmaceutical Research. 25, 12, p. 2769-2777

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: Characterization of conditions for affinity and transport experiments in Caco-2 cells.

    Larsen, M., Larsen, Birger Brodin, Frølund, Bente & Nielsen, C. U., 2008, In: European Journal of Pharmaceutical Sciences. 35, 1-2, p. 86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Palladium-catalyzed monoamination of dihalogenated benzenes

    Larsen, S. B., Bang-Andersen, B., Johansen, Tommy Nørskov & Jørgensen, M., 2008, In: Tetrahedron. 64, 13, p. 2938-2950

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    QSAR models for the human H+/peptide symporter, hPEPT1: Affinity prediction using alignment-independent descriptors

    Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2008, In: Journal of Chemical Information and Modeling. 48, 1, p. 233-241

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Assessment of drug release from oil depot formulations using an in vitro model: Potential applicability in accelerated release testing

    Larsen, Susan Weng, Jessen, M. N. B., Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Development and Industrial Pharmacy. 34, 3, p. 297-304

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In: European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies

    Lauridsen, M., Maher, A. D., Keun, H., Lindon, J. C., Nicholson, J. K., Nyberg, N. T., Hansen, S. H., Cornett, Claus & Jaroszewski, J. W., 2008, In: Analytical Chemistry. 80, 9, p. 3365-3371

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Simultaneous measurement of liquid-phase and solid-phase transformation kinetics in rotating disc and channel flow cell dissolution devices

    Lehto, P., Aaltonen, J., Niemelä, P., Rantanen, Jukka, Hirvonen, J., Tanninen, V. P. & Peltonen, L., 2008, In: Internation Journal of Pharmaceutics. 363, 1-2, p. 66-72

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Environmental risk assessment of ivermectin - A case study with a veterinary pharmaceutical

    Liebig, M., Fernandez, A. A., Blübaum-Gronau, E., Boxall, A., Duis, K., Egeler, P., Fenner, K., Fink, G., Garric, J., Halling-Sørensen, B., Jensen, J., Knacker, T., Krogh, K. A., Küster, A., Pope, L., Römbke, J., Rönnefahrt, I., Argüello, P. S., Schneider, M., Tait, A. & 3 others, Tarazona, J., Ternes, T. & Werhan, A., 2008, World under stress: scientific and applied issues in environmental toxicology and chemistry. Society of Environmental Toxicology and Chemistry, p. 28-28

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  36. Published

    Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments

    Liljander, M., Andersson, Åsa, Holmdahl, R. & Mattsson, R., 2008, In: Arthritis Research & Therapy. 10, 4, p. R88 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Do family practitioners in Lithuania inform their patients about adverse effects of common medications?

    Liseckiene, I., Liubarskiene, Z., Jacobsen, Ramune, Valius, L. & Norup, M. S., 2008, In: Journal of Medical Ethics. 34, 3, p. 137-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

    Lue, B., Nielsen, F. S., Magnussen, T., Schou, H. M., Kristensen, K., Jacobsen, L. O. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 648-657

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    COX-1 inhibition of Heteromorpha arborescens

    Lundgaard, N. H., Prior, R. M., Light, M. E., Stafford, G. I., van Staden, J. & Jäger, A. K., 2008, In: South African Journal of Botany. 74, 2, p. 335-337

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    GMP - three letters with many interpretations:  Protection of patients or killing the clinical and research applications of PET?

    Långström, B. & Honoré, P. G. H., 2008, In: European Journal of Nuclear Medicine and Molecular Imaging. 35, 4, p. 693-694

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    GABA-transportører: håb om bedre epilepsibehandling

    Madsen, K. K., Clausen, Rasmus Prætorius, Larsson, O. M. & Schousboe, Arne, 2008, In: Lægemiddelforskning. p. 22-24

    Research output: Contribution to journalJournal articleCommunication

  43. Published

    Pharmacological manipulation of extrasynaptic GABA transporters: implications for epilepsy management

    Madsen, K. K., Ebert, B., Larsson, O. M., Clausen, Rasmus Prætorius, Schousboe, Arne & White, H. S., 2008, In: Epilepsia. Suppl. 7, p. 347

    Research output: Contribution to journalConference abstract in journalResearch

  44. Published

    Regulation of excitation by GABA neurotransmission: Focus on metabolism and transport

    Madsen, K. K., Larsson, O. M. & Schousboe, Arne, 2008, In: Results and Problems in Cell Differentiation. 44, p. 201-221

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Bioactivation of diclofenac in vitro and in vivo: correlation to electrochemical studies

    Madsen, K. G., Skonberg, C., Jurva, U., Cornett, Claus, Hansen, S. H., Johansen, Tommy Nørskov & Olsen, J., 2008, In: Chemical Research in Toxicology. 21, 5, p. 1107-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Contribution of South African plants to medicinal plant biotechnology

    Makunga, N. P., Jäger, A. K. & van Staden, J., 2008, In: South African Journal of Botany. 2, p. 372

    Research output: Contribution to journalConference abstract in journalResearch

  47. Published

    Drying methods for protein pharmaceuticals

    Maltesen, M. J. & van de Weert, Marco, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 81-88

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Quality by design: Spray drying of insulin intended for inhalation

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 828-838

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Exposure assessment methods for veterinary and human use medicines in the environment: PEC vs MEC comparisons

    Metcalfe, C. D., Alder, A. C., Halling-Sørensen, B., Krogh, K. A., Fenner, K., Larsbo, M., Straub, J. O., Ternes, T. A., Topp, E., Lapen, D. R. & Boxall, A. B. A., 2008, Pharmaceuticals in the environment: Sources, fate, effects and risks. Kümmerer, K. (ed.). Berlin Heidelberg: Springer, p. 147 - 171

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  50. Published

    Hydroxypropyl methylcellulose-controlled crystallization of erythromycin a dihydrate crystals with modified morphology

    Mirza, S., Miroshnyk, I., Heinämäki, J., Rantanen, Jukka, Antikainen, O., Vuorela, P., Vuorela, H. & Yliruusi, J., 2008, In: Crystal Growth & Design. 8, 10, p. 3526-3531

    Research output: Contribution to journalJournal articleResearchpeer-review