Research areas

  1. Published

    Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies

    Hewitt, N. J., Lechón, M. J. G., Houston, J. B., Hallifax, D., Brown, H. S., Maurel, P., Kenna, J. G., Gustavsson, L., Lohmann, C., Skonberg, C., Guillouzo, A., Tuschl, G., Li, A. P., LeCluyse, E., Groothuis, G. M. M. & Hengstler, J. G., 2007, In: Drug Metabolism Reviews. 39, 1, p. 159-234

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Probabilistic environmental risk characterization of pharmaceuticals in sewage treatment plant discharges

    Christensen, A. M., Markussen, Bo, Baun, A. & Halling-Sørensen, B., 2009, In: Chemosphere. 77, 3, p. 351-358

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Probalistic ecological risk assessment of multiple pharmaceuticals in sewage treatment plant effluent

    Christensen, A. M., Baun, A. & Halling-Sørensen, B., 2008, World under stress: scientific and applied issues in environmental toxicology and chemistry. Society of Environmental Toxicology and Chemistry, p. 46-46

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsCommissioned

  4. Published

    Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles

    Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists

    Jensen, Anders A., Begum, N., Vogensen, S. B., Knapp, K. M., Gundertofte, K., Dzyuba, S. V., Ishii, H., Nakanishi, K., Kristiansen, Uffe & Strømgaard, Kristian, 2007, In: Journal of Medicinal Chemistry. 50, 7, p. 1610-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Process analytical applications of Raman spectroscopy

    Rantanen, Jukka, 2007, In: Journal of Pharmacy and Pharmacology. 59, 2, p. 171-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Prodrugs

    Steffansen, B., Thomsen, A. E. & Frøkjær, Sven, 2003, Estimation of solubility, permeability, absorption and bioavaibility. van de Waterbeemd, H., Lennernäs, H. & Artursson, P. (eds.). Weinheim: Wiley-VCH, p. 532-546

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  8. Published

    Product class 34: arylhydrazines

    Rasmussen, L. K. & Begtrup, M., 2007, Science of synthesis: Houben-Weyl methods of molecular transformations. Category 4: compounds with two carbon-heteroatom bonds, volume 31b: Arene-X(X = N, P). Ramsden, C. A. (ed.). Stuttgart: Thieme Medical Publishers, Vol. 31b. p. 1773-1827

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  9. Published

    Production and nutritional aspects of human milk fat substitutes

    Mu, Huiling, 2010, In: Lipid Technology. 22, 6, p. 126-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In: Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat

    Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Protecting ecosystem health: facing the challange of a blobally changing environment: Organic farming practices strongly influence the PAH degradation potential of agricultural soil

    Styrishave, Bjarne, Johnsen, A. R., Magid, J., Aamand, J. & Halling-Sørensen, B., 2009.

    Research output: Contribution to conferencePosterResearch

  13. Published
  14. Published
  15. Published

    Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence  (TIRF)

    Jørgensen, Lene, Krøyer Wood, G., Rosenkrands, I., Petersen, C. & Christensen, D., 2009, In: Journal of Liposome Research. 19, 2, p. 99-104

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Protein and energy metabolism of young male Wistar rats fed conjugated linoleic acid as structured triacylglycerol

    Jørgensen, H., Hørup Hansen, C., Mu, Huiling & Jakobsen, K., 2010, In: Archives of Animal Nutrition. 64, 4, p. 322-336

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Protein comparability using in vitro methods

    Fanø, M., 2011, Det Farmaceutiske Fakultet.

    Research output: Book/ReportPh.D. thesisResearch

  19. Published

    Protein pharmaceuticals

    van de Weert, Marco & Møller, E. H., 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 35-36

    Research output: Contribution to journalEditorialResearch

  20. Published

    Protein-protein interaktion: et nyt mål for udvikling af lægemidler

    Bach, Anders, Gottschalk, M., Kristensen, Anders Skov & Strømgaard, Kristian, 2008, In: Lægemiddelforskning. p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  21. Published

    Proteiner i lægemidler - de sætter sig alle de forkerte steder

    Baldursdóttir, S. G., Nielsen, S. H., Fullerton, M. & Jørgensen, Lene, 2010, In: Lægemiddelforskning. 2010, p. 43-45

    Research output: Contribution to journalJournal articleResearch

  22. Published

    Psychotropic constituents of Mentha aquatica L.

    van Staden, J., Stafford, G. I., Almqvist, J. P., Vangsøe, S. A. K., Olsen, H. T., Christensen, Søren Brøgger, Adsersen, A. & Jäger, A. K., 2007.

    Research output: Contribution to conferencePosterResearch

  23. Published

    Purification, crystallization and preliminary X-ray diffraction of the G3BP1 NTF2-like domain

    Vognsen, T., Möller, I. R. & Kristensen, O., 1 Jan 2011, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 67, Pt 1, p. 48-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    QSAR models for the human H+/peptide symporter, hPEPT1: Affinity prediction using alignment-independent descriptors

    Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2008, In: Journal of Chemical Information and Modeling. 48, 1, p. 233-241

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Qualitative in situ analysis of multiple solid-state forms using spectroscopy and partial least squares discriminant modeling

    Kogermann, K., Aaltonen, J., Strachan, C. J., Pöllänen, K., Veski, P., Heinämäki, J., Yliruusi, J. & Rantanen, Jukka, 2007, In: Journal of Pharmaceutical Sciences. 96, 7, p. 1802-1820

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Quality assessment of Tulbaghia rhizomes

    Jäger, A. & Stafford, G. I., Sep 2012, In: South African Journal of Botany. 82, p. 92-98 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Quality by design: Spray drying of insulin intended for inhalation

    Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 828-838

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Quality indicators of preventable adverse drug events in patients with type 2 diabetes: application of a new register-based model

    Thomsen, L. A., 2009, København: Museum Tusculanum. 30 p.

    Research output: Book/ReportPh.D. thesisResearch

  29. Published

    Quantitative HPLC-ICP-MC analysis of antimony redox speciation in complex sample matrices: new insights into the Sb-chemistry causing poor chromatographic recoveries

    Hansen, C., Schmidt, B., Larsen, E. H., Gammelgaard, Bente, Stürup, Stefan & Hansen, H. R., 2011, In: Analyst. 136, 5, p. 996-1002

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Quantitative Pharmacology – pharmacometrics: a vision for an educational programme in Denmark

    Honoré, P. G. H., Bjerrum, Ole Jannik, Ingwersen, S. H., Thygeson, P., Kristensen, K. & Larsen, F., 2010.

    Research output: Contribution to conferencePosterCommunication

  31. Published

    Quantitative chemical transformations for the synthesis and modification of peptidomimetics on solid phase

    Le Quement, S. T., 2007, København: Det Farmaceutiske Fakultet. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  32. Published

    Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists

    Mosley, C. A., Acker, T. M., Hansen, K. B., Mullasseril, P., Andersen, K. T., Le, P., Vellano, K. M., Bräuner, Hans, Liotta, D. C. & Traynelis, S. F., 2010, In: Journal of Medicinal Chemistry. 53, 15, p. 5476-5490

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes

    Zaretzki, J., Rydberg, P., Bergeron, C., Bennett, K. P., Olsen, L. & Breneman, C. M., 2012, In: Journal of Chemical Information and Modeling. 52, 6, p. 1637-1659

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    RS-predictor: a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4

    Zaretzki, J., Bergeron, C., Rydberg, P., Huang, T., Bennett, K. P. & Breneman, C. M., 25 Jul 2011, In: Journal of Chemical Information and Modeling. 51, 7, p. 1667-1689

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Radioiododestannyllation of novel GHB neuroreceptor ligands

    Pedersen, M. H. F., Høg, S., Wellendorph, Petrine & Martiny, L., 2010, In: Journal of Labelled Compounds and Radiopharmaceuticals. 5-6, p. 318-320

    Research output: Contribution to journalConference articleResearchpeer-review

  36. Published

    Raman spectroscopy for quantitative analysis of pharmaceutical solids

    Strachan, C. J., Rades, Thomas, Gordon, K. C. & Rantanen, Jukka, 2007, In: Journal of Pharmacy and Pharmacology. 59, 2, p. 179-192

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides

    Pedersen, J. T., Teilum, Kaare, Heegaard, N. H. H., Østergaard, Jesper, Adolph, H. & Hemmingsen, Lars Bo Stegeager, 2011, In: Angewandte Chemie International Edition. 50, 11, p. 2532-2535 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  38. Published

    Rapid solid-state analysis of freeze-dried protein formulations using NIR and raman spectroscopies

    Grohganz, Holger, Gildemyn, D., Skibsted, E., Flink, J. M. & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Rational design of a-conotoxin analogues targeting a7 nicotinic acetylcholine receptors: Improved antagonistic activity by incorporation of proline derivatives

    Armishaw, C., Jensen, Anders A., Balle, T., Clark, R. J., Harpsøe, Kasper, Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, In: Journal of Biological Chemistry. 284, 14, p. 9498-9512

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Rationales behind the choice of administration form with fentanyl: Delphi survey among Danish general practitioners

    Jacobsen, Ramune, Møldrup, C. & Christrup, Lona Louring, 2010, In: Journal of Opioid Management. 6, 4, p. 259-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Reaction between drug substances and pharmaceutical excipients: formation of citric acid esters and amides of carvedilol in the solid state

    Larsen, J., Cornett, Claus, Jaroszewski, J. W. & Hansen, S. H., 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, 1, p. 11-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Reaction between drug substances and pharmaceutical excipients: Formation of esters between cetirizine and polyols

    Yu, H., Cornett, Claus, Larsen, J. & Hansen, S. H., 2010, In: Journal of Pharmaceutical and Biomedical Analysis. 53, p. 745-750

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Real-time UV imaging of nicotin release from transdermal patch

    Østergaard, Jesper, Meng-Lund, E., Larsen, Susan Weng, Larsen, C. S., Petersson, K., Lenke, J. & Jensen, H., 2010, In: Pharmaceutical Research. 27, p. 2614-2623

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix

    Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Real-time monitoring of the progerss of polymerization reactions directly on surfaces at open atmosphere by ambient mass spectrometry

    Nørgaard, A. W., Vaz, B. G., Lauritsen, F. R. & Eberlin, M. N., 2010, In: Rapid Communications in Mass Spectrometry. 24, p. 3441-3446

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Recent advances in the characterization of lipid-based nanocarriers

    Yaghmur, Anan & Rappolt, M., 2011, Nanotechnologies for solubilization and delivery in foods, cosmetics and pharmaceuticals. Garti, N. & Amar-Yuli, I. (eds.). Pennsylvania: DEStech Publications, Inc., p. 188-202

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  47. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters

    Andersen, J., Kristensen, Anders Skov, Bang-Andersen, B. & Strømgaard, Kristian, 2009, In: Chemical Communications. 25, p. 3677-3692

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients

    Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230

    Research output: Contribution to journalReviewResearch

  49. Published

    Receptorer i historisk og nutidig belysning

    Bräuner, Hans, 2009, In: Carlsbergfondet. Aarsskrift. p. 30-35

    Research output: Contribution to journalJournal articleCommunication

  50. Published

    Receptors: Structure, function, and pharmacology

    Bräuner, Hans, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 189-205

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation