Research areas

  1. Published

    Metabolic profiling based on two-dimensional J-resolved 1H NMR data and parallel factor analysis

    Yilmaz, A., Nyberg, N. T. & Jaroszewski, J. W., 27 Sep 2011, In : Analytical Chemistry. 83, 21, p. 8278-8285

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In : Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A highly selective agonist for the metabotropic glutamate receptor mGluR2

    Nielsen, S. D., Fulco, M., Serpi, M., Nielsen, Birgitte, Hansen, M. B., Hansen, K. L., Thomsen, C., Brodbeck, R., Bräuner-Osborne, Hans, Pellicciari, R., Norrby, P., Greenwood, J. R. & Clausen, Rasmus Prætorius, 23 Sep 2011, In : MedChemComm. 2, 11, p. 1120-1124

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats

    Stefkov, G., Kulevanova, S., Miova, B., Dinevska-Kjovkarovska, S., Mølgaard, Per, Jäger, A. K. & Josefsen, K., 1 Sep 2011, In : Pharmaceutical Biology. 49, 9, p. 885-892

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

    Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In : Neurochemistry International. 59, 4, p. 482-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Ubiquitous plant compounds disturb cell-based assays

    Saaby, L. & Jäger, A. K., 1 Sep 2011, In : Journal of Ethnopharmacology. 137, 1, p. 942-943

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model

    Rasmussen, Rune Skovgaard, Overgaard, K., Kristiansen, Uffe & Johansen, Flemming Fryd, Sep 2011, In : Neurological Research. 33, 7, p. 774-782 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Do two different reaction mechanisms contribute to the hydroxylation of primary amines by cytochrome P450?

    Rydberg, P. & Olsen, L., Sep 2011, In : Journal of Chemical Theory and Computation. 7, 10, p. 3399-3404

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Evolution and applications of plant pathway resources and databases

    Sucaet, Y. & Deva, T., Sep 2011, In : Briefings in Bioinformatics. 12, 5, p. 530-544

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice

    Richner, M., Bjerrum, Ole Jannik, Nykjær, A. & Vaegter, C. B., 18 Aug 2011, In : Journal of Visualized Experiments. 54, p. e3092

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline

    Andreasen T., Jesper, Henningsen, K., Bate, S., Christiansen, S. & Wiborg, O., 1 Aug 2011, In : Journal of Psychopharmacology. 25, 8, p. 1134-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

    Lund, Trine Meldgaard, Obel, L. F., Risa, Ø. & Sonnewald, U., 1 Aug 2011, In : Neurochemistry International. 59, 2, p. 309-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Extraction and detection of Ionophores in the Aquatic Environment

    Bak, S. A., Hansen, M., Krogh, K. A., Björklund, E. & Halling-Sørensen, B., Aug 2011.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  16. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging

    Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, Henrik, Aug 2011, In : Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1

    Thorn, K., Nielsen, C. U., Jakobsen, P., Steffansen, B., Zercher, C. K. & Begtrup, M., Aug 2011, In : Bioorganic & Medicinal Chemistry Letters. 21, 15, p. 4597-4601

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Open3DALIGN: an open-source software aimed at unsupervised ligand alignment

    Tosco, P., Balle, T. & Shiri, F., 27 Jul 2011, In : Journal of Computer - Aided Molecular Design. 25, 8, p. 777-783

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors

    Harpsøe, Kasper, Ahring, P. K., Christensen, J. K., Jensen, M. L., Peters, D. & Balle, T., 27 Jul 2011, In : Journal of Neuroscience. 31, 30, p. 10759-10766

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    RS-predictor: a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4

    Zaretzki, J., Bergeron, C., Rydberg, P., Huang, T., Bennett, K. P. & Breneman, C. M., 25 Jul 2011, In : Journal of Chemical Information and Modeling. 51, 7, p. 1667-1689

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines

    Nielsen, S. D., Smith, G. P., Begtrup, M. & Kristensen, Jesper Langgaard, 22 Jul 2011, In : Tetrahedron. 67, 29, p. 5261-5267

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

    Andersen, J., Stuhr-Hansen, N., Dorvil, Linda Grønborg, Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A. D., Bøgesø, K. P., Bang-Andersen, B., Kristensen, Anders Skov & Strømgaard, Kristian, 19 Jul 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol

    Madsen, K. K., Ebert, B., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 1 Jul 2011, In : Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 214-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Temocene: the porphycene analogue of temoporfin (Foscan®)

    Garcia-Diaz, M., Sanchez-Garcia, D., Nonell, S., Soriano, J., Villanueva, A., Stockert, J. C., Canete, M., Sagrista, M. L. & Mora, M., 1 Jul 2011, In : MedChemComm. 2, 7, p. 616-619 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Chemical composition and biological screening of Capsella bursa-pastoris

    Grosso, C., Vinholes, J., Silva, L. R., Guedes de Pinho, P., Goncalves, R. F., Valentao, P., Jäger, A. K. & Andrade, P. B., Jul 2011, In : Revista Brasileira de Farmacognosia. 21, 4, p. 635-644

    Research output: Contribution to journalJournal articleResearchpeer-review

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