Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort. / Tuffier, Stéphane; Zhang, Jiawei; Bergmann, Marie; So, Rina; Napolitano, George Maria; Cole-Hunter, Thomas; Maric, Matija; Antic, Sonja; Brandt, Jørgen; Ketzel, Matthias; Loft, Steffen; Lim, Youn-Hee; Andersen, Zorana Jovanovic.

In: Alzheimer's & Dementia, 2024.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Tuffier, S, Zhang, J, Bergmann, M, So, R, Napolitano, GM, Cole-Hunter, T, Maric, M, Antic, S, Brandt, J, Ketzel, M, Loft, S, Lim, Y-H & Andersen, ZJ 2024, 'Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort', Alzheimer's & Dementia. https://doi.org/10.1002/alz.13814

APA

Tuffier, S., Zhang, J., Bergmann, M., So, R., Napolitano, G. M., Cole-Hunter, T., Maric, M., Antic, S., Brandt, J., Ketzel, M., Loft, S., Lim, Y-H., & Andersen, Z. J. (2024). Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort. Alzheimer's & Dementia. https://doi.org/10.1002/alz.13814

Vancouver

Tuffier S, Zhang J, Bergmann M, So R, Napolitano GM, Cole-Hunter T et al. Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort. Alzheimer's & Dementia. 2024. https://doi.org/10.1002/alz.13814

Author

Tuffier, Stéphane ; Zhang, Jiawei ; Bergmann, Marie ; So, Rina ; Napolitano, George Maria ; Cole-Hunter, Thomas ; Maric, Matija ; Antic, Sonja ; Brandt, Jørgen ; Ketzel, Matthias ; Loft, Steffen ; Lim, Youn-Hee ; Andersen, Zorana Jovanovic. / Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort. In: Alzheimer's & Dementia. 2024.

Bibtex

@article{be37c644e3304d0c8a8e0ad444507b9f,
title = "Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort",
abstract = "INTRODUCTION: We examined the association of long-term exposure to air pollution and road traffic noise with dementia incidence in the Danish Nurse Cohort.METHODS: Female nurses were followed for dementia incidence (hospital contact or medication prescription) from 1993/1999 to 2020. Air pollution and road traffic noise levels were estimated at nurses' residences, and their associations with dementia were examined using Cox regression models.RESULTS: Of 25,233 nurses 1409 developed dementia. Particulate matter with a diameter of ≤2.5 µm (PM 2.5) was associated with dementia incidence, after adjusting for lifestyle, socioeconomic status, and road traffic noise (hazard ratio [95% confidence interval] 1.35 [1.15-1.59] per interquartile range of 2.6 µg/m 3). There was no association of PM2.5 with dementia in physically active nurses. Association with road traffic noise diminished after adjusting for PM₂.₅ (1.02 [0.93-1.11] per 7.6 dB). DISCUSSION: Long-term exposure to air pollution increases risk of dementia, and physical activity may moderate this risk.HIGHLIGHTS: Long-term exposure to air pollution was associated with increased risk of dementia among female nurses from the Danish Nurse Cohort. Association of air pollution with dementia was independent of road traffic noise. Association of road traffic noise with dementia diminished after adjusting for air pollution. Physical activity moderated adverse effects of air pollution on dementia.",
keywords = "Faculty of Health and Medical Sciences, air pollution, cohort studies, dementia, Europe, incidence, noise transportation, nurses, physical activity, women",
author = "St{\'e}phane Tuffier and Jiawei Zhang and Marie Bergmann and Rina So and Napolitano, {George Maria} and Thomas Cole-Hunter and Matija Maric and Sonja Antic and J{\o}rgen Brandt and Matthias Ketzel and Steffen Loft and Youn-Hee Lim and Andersen, {Zorana Jovanovic}",
note = "{\textcopyright} 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.",
year = "2024",
doi = "10.1002/alz.13814",
language = "English",
journal = "Alzheimer's & Dementia",
issn = "1552-5260",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort

AU - Tuffier, Stéphane

AU - Zhang, Jiawei

AU - Bergmann, Marie

AU - So, Rina

AU - Napolitano, George Maria

AU - Cole-Hunter, Thomas

AU - Maric, Matija

AU - Antic, Sonja

AU - Brandt, Jørgen

AU - Ketzel, Matthias

AU - Loft, Steffen

AU - Lim, Youn-Hee

AU - Andersen, Zorana Jovanovic

N1 - © 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.

PY - 2024

Y1 - 2024

N2 - INTRODUCTION: We examined the association of long-term exposure to air pollution and road traffic noise with dementia incidence in the Danish Nurse Cohort.METHODS: Female nurses were followed for dementia incidence (hospital contact or medication prescription) from 1993/1999 to 2020. Air pollution and road traffic noise levels were estimated at nurses' residences, and their associations with dementia were examined using Cox regression models.RESULTS: Of 25,233 nurses 1409 developed dementia. Particulate matter with a diameter of ≤2.5 µm (PM 2.5) was associated with dementia incidence, after adjusting for lifestyle, socioeconomic status, and road traffic noise (hazard ratio [95% confidence interval] 1.35 [1.15-1.59] per interquartile range of 2.6 µg/m 3). There was no association of PM2.5 with dementia in physically active nurses. Association with road traffic noise diminished after adjusting for PM₂.₅ (1.02 [0.93-1.11] per 7.6 dB). DISCUSSION: Long-term exposure to air pollution increases risk of dementia, and physical activity may moderate this risk.HIGHLIGHTS: Long-term exposure to air pollution was associated with increased risk of dementia among female nurses from the Danish Nurse Cohort. Association of air pollution with dementia was independent of road traffic noise. Association of road traffic noise with dementia diminished after adjusting for air pollution. Physical activity moderated adverse effects of air pollution on dementia.

AB - INTRODUCTION: We examined the association of long-term exposure to air pollution and road traffic noise with dementia incidence in the Danish Nurse Cohort.METHODS: Female nurses were followed for dementia incidence (hospital contact or medication prescription) from 1993/1999 to 2020. Air pollution and road traffic noise levels were estimated at nurses' residences, and their associations with dementia were examined using Cox regression models.RESULTS: Of 25,233 nurses 1409 developed dementia. Particulate matter with a diameter of ≤2.5 µm (PM 2.5) was associated with dementia incidence, after adjusting for lifestyle, socioeconomic status, and road traffic noise (hazard ratio [95% confidence interval] 1.35 [1.15-1.59] per interquartile range of 2.6 µg/m 3). There was no association of PM2.5 with dementia in physically active nurses. Association with road traffic noise diminished after adjusting for PM₂.₅ (1.02 [0.93-1.11] per 7.6 dB). DISCUSSION: Long-term exposure to air pollution increases risk of dementia, and physical activity may moderate this risk.HIGHLIGHTS: Long-term exposure to air pollution was associated with increased risk of dementia among female nurses from the Danish Nurse Cohort. Association of air pollution with dementia was independent of road traffic noise. Association of road traffic noise with dementia diminished after adjusting for air pollution. Physical activity moderated adverse effects of air pollution on dementia.

KW - Faculty of Health and Medical Sciences

KW - air pollution

KW - cohort studies

KW - dementia

KW - Europe

KW - incidence

KW - noise transportation

KW - nurses

KW - physical activity

KW - women

U2 - 10.1002/alz.13814

DO - 10.1002/alz.13814

M3 - Journal article

C2 - 38716818

JO - Alzheimer's & Dementia

JF - Alzheimer's & Dementia

SN - 1552-5260

ER -

ID: 391264970