Status og perspektiver for behandling af de kroniske myeloproliferative neoplasier
Research output: Contribution to journal › Journal article › Research › peer-review
Polycythaemia vera, essential thrombocytosis and primary myelofibrosis are closely related, clonal myeloproliferative neoplasms. Our knowledge of the underlying molecular mechanisms driving these diseases has increased dramatically during the latest ten years. Traditionally, treatment of these malignancies has focused on lowering their inherent thromboembolic risk but with the discovery of the JAK2-V617F mutation and most recently the calreticulin mutations new therapeutic options such as interferon-alpha, JAK2-inhibitors and statins are being contemplated. This article reviews these new treatment options.
Translated title of the contribution | Status and perspectives on chronic myeloproliferative neoplasm treatment |
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Original language | Danish |
Journal | Ugeskrift for Laeger |
Volume | 177 |
Issue number | 26 |
Pages (from-to) | 2522-2526 |
Number of pages | 5 |
ISSN | 0041-5782 |
Publication status | Published - 21 Dec 2015 |
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