The Current Status and Work of Three Rs Centres and Platforms in Europe*

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The Current Status and Work of Three Rs Centres and Platforms in Europe*. / Neuhaus, Winfried; Reininger-Gutmann, Birgit; Rinner, Beate; Plasenzotti, Roberto; Wilflingseder, Doris; De Kock, Joery; Vanhaecke, Tamara; Rogiers, Vera; Jírová, Dagmar; Kejlová, Kristina; Knudsen, Lisbeth E.; Nielsen, Rasmus Normann; Kleuser, Burkhard; Kral, Vivian; Thöne-Reineke, Christa; Hartung, Thomas; Pallocca, Giorgia; Rovida, Costanza; Leist, Marcel; Hippenstiel, Stefan; Lang, Annemarie; Retter, Ida; Krämer, Stephanie; Jedlicka, Peter; Ameli, Katharina; Fritsche, Ellen; Tigges, Julia; Kuchovská, Eliška; Buettner, Manuela; Bleich, Andre; Baumgart, Nadine; Baumgart, Jan; Meinhardt, Marcus W.; Spanagel, Rainer; Chourbaji, Sabine; Kränzlin, Bettina; Seeger, Bettina; von Köckritz-Blickwede, Maren; Sánchez-Morgado, José M.; Galligioni, Viola; Ruiz-Pérez, Daniel; Movia, Dania; Prina-Mello, Adriele; Ahluwalia, Arti; Chiono, Valeria; Gutleb, Arno C.; Schmit, Marthe; van Golen, Bea; van Weereld, Leane; Kienhuis, Anne; van Oort, Erica; van der Valk, Jan; Smith, Adrian; Roszak, Joanna; Stępnik, Maciej; Sobańska, Zuzanna; Reszka, Edyta; Olsson, I. Anna S.; Franco, Nuno Henrique; Sevastre, Bogdan; Kandarova, Helena; Capdevila, Sara; Johansson, Jessica; Svensk, Emma; Cederroth, Christopher R.; Sandström, Jenny; Ragan, Ian; Bubalo, Nataliia; Kurreck, Jens; Spielmann, Horst.

In: Alternatives to Laboratory Animals, Vol. 50, No. 6, 2022, p. 381-413.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Neuhaus, W, Reininger-Gutmann, B, Rinner, B, Plasenzotti, R, Wilflingseder, D, De Kock, J, Vanhaecke, T, Rogiers, V, Jírová, D, Kejlová, K, Knudsen, LE, Nielsen, RN, Kleuser, B, Kral, V, Thöne-Reineke, C, Hartung, T, Pallocca, G, Rovida, C, Leist, M, Hippenstiel, S, Lang, A, Retter, I, Krämer, S, Jedlicka, P, Ameli, K, Fritsche, E, Tigges, J, Kuchovská, E, Buettner, M, Bleich, A, Baumgart, N, Baumgart, J, Meinhardt, MW, Spanagel, R, Chourbaji, S, Kränzlin, B, Seeger, B, von Köckritz-Blickwede, M, Sánchez-Morgado, JM, Galligioni, V, Ruiz-Pérez, D, Movia, D, Prina-Mello, A, Ahluwalia, A, Chiono, V, Gutleb, AC, Schmit, M, van Golen, B, van Weereld, L, Kienhuis, A, van Oort, E, van der Valk, J, Smith, A, Roszak, J, Stępnik, M, Sobańska, Z, Reszka, E, Olsson, IAS, Franco, NH, Sevastre, B, Kandarova, H, Capdevila, S, Johansson, J, Svensk, E, Cederroth, CR, Sandström, J, Ragan, I, Bubalo, N, Kurreck, J & Spielmann, H 2022, 'The Current Status and Work of Three Rs Centres and Platforms in Europe*', Alternatives to Laboratory Animals, vol. 50, no. 6, pp. 381-413. https://doi.org/10.1177/02611929221140909

APA

Neuhaus, W., Reininger-Gutmann, B., Rinner, B., Plasenzotti, R., Wilflingseder, D., De Kock, J., Vanhaecke, T., Rogiers, V., Jírová, D., Kejlová, K., Knudsen, L. E., Nielsen, R. N., Kleuser, B., Kral, V., Thöne-Reineke, C., Hartung, T., Pallocca, G., Rovida, C., Leist, M., ... Spielmann, H. (2022). The Current Status and Work of Three Rs Centres and Platforms in Europe*. Alternatives to Laboratory Animals, 50(6), 381-413. https://doi.org/10.1177/02611929221140909

Vancouver

Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J et al. The Current Status and Work of Three Rs Centres and Platforms in Europe*. Alternatives to Laboratory Animals. 2022;50(6):381-413. https://doi.org/10.1177/02611929221140909

Author

Neuhaus, Winfried ; Reininger-Gutmann, Birgit ; Rinner, Beate ; Plasenzotti, Roberto ; Wilflingseder, Doris ; De Kock, Joery ; Vanhaecke, Tamara ; Rogiers, Vera ; Jírová, Dagmar ; Kejlová, Kristina ; Knudsen, Lisbeth E. ; Nielsen, Rasmus Normann ; Kleuser, Burkhard ; Kral, Vivian ; Thöne-Reineke, Christa ; Hartung, Thomas ; Pallocca, Giorgia ; Rovida, Costanza ; Leist, Marcel ; Hippenstiel, Stefan ; Lang, Annemarie ; Retter, Ida ; Krämer, Stephanie ; Jedlicka, Peter ; Ameli, Katharina ; Fritsche, Ellen ; Tigges, Julia ; Kuchovská, Eliška ; Buettner, Manuela ; Bleich, Andre ; Baumgart, Nadine ; Baumgart, Jan ; Meinhardt, Marcus W. ; Spanagel, Rainer ; Chourbaji, Sabine ; Kränzlin, Bettina ; Seeger, Bettina ; von Köckritz-Blickwede, Maren ; Sánchez-Morgado, José M. ; Galligioni, Viola ; Ruiz-Pérez, Daniel ; Movia, Dania ; Prina-Mello, Adriele ; Ahluwalia, Arti ; Chiono, Valeria ; Gutleb, Arno C. ; Schmit, Marthe ; van Golen, Bea ; van Weereld, Leane ; Kienhuis, Anne ; van Oort, Erica ; van der Valk, Jan ; Smith, Adrian ; Roszak, Joanna ; Stępnik, Maciej ; Sobańska, Zuzanna ; Reszka, Edyta ; Olsson, I. Anna S. ; Franco, Nuno Henrique ; Sevastre, Bogdan ; Kandarova, Helena ; Capdevila, Sara ; Johansson, Jessica ; Svensk, Emma ; Cederroth, Christopher R. ; Sandström, Jenny ; Ragan, Ian ; Bubalo, Nataliia ; Kurreck, Jens ; Spielmann, Horst. / The Current Status and Work of Three Rs Centres and Platforms in Europe*. In: Alternatives to Laboratory Animals. 2022 ; Vol. 50, No. 6. pp. 381-413.

Bibtex

@article{eaf02bd82cb7463ead984db034d7888f,

title = "The Current Status and Work of Three Rs Centres and Platforms in Europe*",

abstract = "The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-called Three Rs, which are the Replacement, Reduction and Refinement of animal use in experiments. ATLA{\textquoteright}s 50th Anniversary year has seen the publication of two articles on European Three Rs centres and platforms. The first of these was about the progressive rise in their numbers and about their founding history; this second part focuses on their current status and activities. This article takes a closer look at their financial and organisational structures, describes their Three Rs focus and core activities (dissemination, education, implementation, scientific quality/translatability, ethics), and presents their areas of responsibility and projects in detail. This overview of the work and diverse structures of the Three Rs centres and platforms is not only intended to bring them closer to the reader, but also to provide role models and show examples of how such Three Rs centres and platforms could be made sustainable. The Three Rs centres and platforms are very important focal points and play an immense role as facilitators of Directive 2010/63/EU {\textquoteleft}on the ground{\textquoteright} in their respective countries. They are also invaluable for the wide dissemination of information and for promoting the implementation of the Three Rs in general.",

keywords = "3R, 3Rs, EU3Rnet, NAM, NAMs, new approach methodologies, non-animal methods, novel approach methodologies",

author = "Winfried Neuhaus and Birgit Reininger-Gutmann and Beate Rinner and Roberto Plasenzotti and Doris Wilflingseder and {De Kock}, Joery and Tamara Vanhaecke and Vera Rogiers and Dagmar J{\'i}rov{\'a} and Kristina Kejlov{\'a} and Knudsen, {Lisbeth E.} and Nielsen, {Rasmus Normann} and Burkhard Kleuser and Vivian Kral and Christa Th{\"o}ne-Reineke and Thomas Hartung and Giorgia Pallocca and Costanza Rovida and Marcel Leist and Stefan Hippenstiel and Annemarie Lang and Ida Retter and Stephanie Kr{\"a}mer and Peter Jedlicka and Katharina Ameli and Ellen Fritsche and Julia Tigges and Eli{\v s}ka Kuchovsk{\'a} and Manuela Buettner and Andre Bleich and Nadine Baumgart and Jan Baumgart and Meinhardt, {Marcus W.} and Rainer Spanagel and Sabine Chourbaji and Bettina Kr{\"a}nzlin and Bettina Seeger and {von K{\"o}ckritz-Blickwede}, Maren and S{\'a}nchez-Morgado, {Jos{\'e} M.} and Viola Galligioni and Daniel Ruiz-P{\'e}rez and Dania Movia and Adriele Prina-Mello and Arti Ahluwalia and Valeria Chiono and Gutleb, {Arno C.} and Marthe Schmit and {van Golen}, Bea and {van Weereld}, Leane and Anne Kienhuis and {van Oort}, Erica and {van der Valk}, Jan and Adrian Smith and Joanna Roszak and Maciej St{\c e}pnik and Zuzanna Soba{\'n}ska and Edyta Reszka and Olsson, {I. Anna S.} and Franco, {Nuno Henrique} and Bogdan Sevastre and Helena Kandarova and Sara Capdevila and Jessica Johansson and Emma Svensk and Cederroth, {Christopher R.} and Jenny Sandstr{\"o}m and Ian Ragan and Nataliia Bubalo and Jens Kurreck and Horst Spielmann",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2022.",

year = "2022",

doi = "10.1177/02611929221140909",

language = "English",

volume = "50",

pages = "381--413",

journal = "ATLA Alternatives to Laboratory Animals",

issn = "0261-1929",

publisher = "Fund for the Replacement of Animals in Medical Experiments",

number = "6",

}

RIS

TY - JOUR

T1 - The Current Status and Work of Three Rs Centres and Platforms in Europe*

AU - Neuhaus, Winfried

AU - Reininger-Gutmann, Birgit

AU - Rinner, Beate

AU - Plasenzotti, Roberto

AU - Wilflingseder, Doris

AU - De Kock, Joery

AU - Vanhaecke, Tamara

AU - Rogiers, Vera

AU - Jírová, Dagmar

AU - Kejlová, Kristina

AU - Knudsen, Lisbeth E.

AU - Nielsen, Rasmus Normann

AU - Kleuser, Burkhard

AU - Kral, Vivian

AU - Thöne-Reineke, Christa

AU - Hartung, Thomas

AU - Pallocca, Giorgia

AU - Rovida, Costanza

AU - Leist, Marcel

AU - Hippenstiel, Stefan

AU - Lang, Annemarie

AU - Retter, Ida

AU - Krämer, Stephanie

AU - Jedlicka, Peter

AU - Ameli, Katharina

AU - Fritsche, Ellen

AU - Tigges, Julia

AU - Kuchovská, Eliška

AU - Buettner, Manuela

AU - Bleich, Andre

AU - Baumgart, Nadine

AU - Baumgart, Jan

AU - Meinhardt, Marcus W.

AU - Spanagel, Rainer

AU - Chourbaji, Sabine

AU - Kränzlin, Bettina

AU - Seeger, Bettina

AU - von Köckritz-Blickwede, Maren

AU - Sánchez-Morgado, José M.

AU - Galligioni, Viola

AU - Ruiz-Pérez, Daniel

AU - Movia, Dania

AU - Prina-Mello, Adriele

AU - Ahluwalia, Arti

AU - Chiono, Valeria

AU - Gutleb, Arno C.

AU - Schmit, Marthe

AU - van Golen, Bea

AU - van Weereld, Leane

AU - Kienhuis, Anne

AU - van Oort, Erica

AU - van der Valk, Jan

AU - Smith, Adrian

AU - Roszak, Joanna

AU - Stępnik, Maciej

AU - Sobańska, Zuzanna

AU - Reszka, Edyta

AU - Olsson, I. Anna S.

AU - Franco, Nuno Henrique

AU - Sevastre, Bogdan

AU - Kandarova, Helena

AU - Capdevila, Sara

AU - Johansson, Jessica

AU - Svensk, Emma

AU - Cederroth, Christopher R.

AU - Sandström, Jenny

AU - Ragan, Ian

AU - Bubalo, Nataliia

AU - Kurreck, Jens

AU - Spielmann, Horst

PY - 2022

Y1 - 2022

N2 - The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-called Three Rs, which are the Replacement, Reduction and Refinement of animal use in experiments. ATLA’s 50th Anniversary year has seen the publication of two articles on European Three Rs centres and platforms. The first of these was about the progressive rise in their numbers and about their founding history; this second part focuses on their current status and activities. This article takes a closer look at their financial and organisational structures, describes their Three Rs focus and core activities (dissemination, education, implementation, scientific quality/translatability, ethics), and presents their areas of responsibility and projects in detail. This overview of the work and diverse structures of the Three Rs centres and platforms is not only intended to bring them closer to the reader, but also to provide role models and show examples of how such Three Rs centres and platforms could be made sustainable. The Three Rs centres and platforms are very important focal points and play an immense role as facilitators of Directive 2010/63/EU ‘on the ground’ in their respective countries. They are also invaluable for the wide dissemination of information and for promoting the implementation of the Three Rs in general.

AB - The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-called Three Rs, which are the Replacement, Reduction and Refinement of animal use in experiments. ATLA’s 50th Anniversary year has seen the publication of two articles on European Three Rs centres and platforms. The first of these was about the progressive rise in their numbers and about their founding history; this second part focuses on their current status and activities. This article takes a closer look at their financial and organisational structures, describes their Three Rs focus and core activities (dissemination, education, implementation, scientific quality/translatability, ethics), and presents their areas of responsibility and projects in detail. This overview of the work and diverse structures of the Three Rs centres and platforms is not only intended to bring them closer to the reader, but also to provide role models and show examples of how such Three Rs centres and platforms could be made sustainable. The Three Rs centres and platforms are very important focal points and play an immense role as facilitators of Directive 2010/63/EU ‘on the ground’ in their respective countries. They are also invaluable for the wide dissemination of information and for promoting the implementation of the Three Rs in general.

KW - 3R

KW - 3Rs

KW - EU3Rnet

KW - NAM

KW - NAMs

KW - new approach methodologies

KW - non-animal methods

KW - novel approach methodologies

U2 - 10.1177/02611929221140909

DO - 10.1177/02611929221140909

M3 - Journal article

C2 - 36458800

AN - SCOPUS:85141021511

VL - 50

SP - 381

EP - 413

JO - ATLA Alternatives to Laboratory Animals

JF - ATLA Alternatives to Laboratory Animals

SN - 0261-1929

IS - 6

ER -

ID: 337594093

Department of Public Health