Age-period-cohort modelling of breast cancer incidence in the Nordic countries.

Research output: Contribution to journalJournal articleResearchpeer-review

K Rostgaard, M Vaeth, H Holst, Mette Madsen, E Lynge

The Nordic countries have experienced a steady increase in breast cancer incidence throughout the past 35 years. We analysed the incidence in Denmark, Finland, Norway and Sweden during the period 1958 to 1992 using age-period-cohort models and taking the systematic mammography screening into account. Assuming the age dependency of the incidence pattern in old age to be common for the Nordic countries, an internal comparison could be made among the four countries of the cohort effects and the period effects. The study indicated that the period effects have been of importance for the increase in breast cancer incidence seen in the Nordic countries. The widespread practice of neglecting the period effects in age-period-cohort analysis of time trends in breast cancer incidence therefore probably needs reconsideration. A key finding was that Danish women born in the 20th century seem to have been exposed to an increasing load of cohort borne breast cancer risk factors not experienced to the same extent by Norwegian women, whereas they were seemingly subjected to the same period effects.
Original languageEnglish
JournalStatistics in Medicine
Volume20
Issue number1
Pages (from-to)47-61
Number of pages14
ISSN0277-6715
Publication statusPublished - 2001

Bibliographical note

Keywords: Adult; Age Factors; Aged; Aged, 80 and over; Breast Neoplasms; Cohort Effect; Cohort Studies; Epidemiologic Factors; Female; Finland; Humans; Incidence; Linear Models; Mammography; Mass Screening; Middle Aged; Models, Statistical; Risk Factors; Scandinavia

    Research areas

  • The Faculty of Health and Medical Sciences - Adult, Age Factors, Aged, Breast Neoplasms, Cohort Effect, Cohort Studies, Epidemiologic Factors, Female, Finland, Humans, Incidence, Linear Models, Mammography, Mass Screening, Middle Aged, Models, Statistical, Risk Factors, Scandinavia

ID: 4850624