Body mass index and height in young adult men in relation to subsequent risk of mood disorder

Research output: Contribution to journalJournal articlepeer-review

Standard

Body mass index and height in young adult men in relation to subsequent risk of mood disorder. / Okholm, Gunhild Tidemann; Jorgensen, Terese Sara Hoj; Rozing, Maarten Pieter; Wium-Andersen, Marie Kim; Wium-Andersen, Ida Kim; Jorgensen, Martin Balslev; Sørensen, Thorkild I. A.; Osler, Merete.

In: European Journal of Epidemiology, Vol. 36, 2021, p. 1065–1074.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Okholm, GT, Jorgensen, TSH, Rozing, MP, Wium-Andersen, MK, Wium-Andersen, IK, Jorgensen, MB, Sørensen, TIA & Osler, M 2021, 'Body mass index and height in young adult men in relation to subsequent risk of mood disorder', European Journal of Epidemiology, vol. 36, pp. 1065–1074. https://doi.org/10.1007/s10654-021-00783-z

APA

Okholm, G. T., Jorgensen, T. S. H., Rozing, M. P., Wium-Andersen, M. K., Wium-Andersen, I. K., Jorgensen, M. B., Sørensen, T. I. A., & Osler, M. (2021). Body mass index and height in young adult men in relation to subsequent risk of mood disorder. European Journal of Epidemiology, 36, 1065–1074. https://doi.org/10.1007/s10654-021-00783-z

Vancouver

Okholm GT, Jorgensen TSH, Rozing MP, Wium-Andersen MK, Wium-Andersen IK, Jorgensen MB et al. Body mass index and height in young adult men in relation to subsequent risk of mood disorder. European Journal of Epidemiology. 2021;36:1065–1074. https://doi.org/10.1007/s10654-021-00783-z

Author

Okholm, Gunhild Tidemann ; Jorgensen, Terese Sara Hoj ; Rozing, Maarten Pieter ; Wium-Andersen, Marie Kim ; Wium-Andersen, Ida Kim ; Jorgensen, Martin Balslev ; Sørensen, Thorkild I. A. ; Osler, Merete. / Body mass index and height in young adult men in relation to subsequent risk of mood disorder. In: European Journal of Epidemiology. 2021 ; Vol. 36. pp. 1065–1074.

Bibtex

@article{4343d9ad4cc547cba3f19799c4273958,
title = "Body mass index and height in young adult men in relation to subsequent risk of mood disorder",
abstract = "Adolescence represents an important period in brain and mental development, which raises the question of whether measures of body size at entry into adult life influence the risk of developing mood disorders. We examined the association of BMI and height in a cohort of young men with risk of mood disorders throughout life. The study included 630,807 Danish men born 1939-1959 and 1983-1997 with measures of height and weight at conscription board examinations. Psychiatrist's diagnosis of mood disorders was obtained from national patient registries from 1969 to 2016. The associations of BMI and height with mood disorders were estimated by Cox proportional hazard regression analyses adjusting for education, cognitive ability, migration status drug and alcohol misuse. During a mean follow-up of 26.3 years, 2,608 (0.6%) and 19,690 (3.1%) men were diagnosed with bipolar disorder and depression, respectively. We found an inverse linear association of BMI with risk of bipolar disorder, whereas the association of BMI with depression was curve-linear with a decline in risk until BMI around 25 kg/m(2), and an almost constant risk across the BMI range above 25 kg/m(2). Height was not associated with bipolar disorder or depression. Comparison of brothers, assumed to share family factors of possible influence on the risk of mood disorders, showed similar results although with wider confidence intervals. BMI in the lower range at men's entry into adulthood is inversely associated with risk of bipolar disorder and depression throughout adult life, whereas height is not related.",
keywords = "Body mass index, Height, Depression, Bipolar disorder, Cohort study, DEPRESSIVE SYMPTOMS, ASSOCIATION, OBESITY, COHORT, SUICIDE, OVERWEIGHT, ANXIETY, HEALTH, TWIN",
author = "Okholm, {Gunhild Tidemann} and Jorgensen, {Terese Sara Hoj} and Rozing, {Maarten Pieter} and Wium-Andersen, {Marie Kim} and Wium-Andersen, {Ida Kim} and Jorgensen, {Martin Balslev} and S{\o}rensen, {Thorkild I. A.} and Merete Osler",
year = "2021",
doi = "10.1007/s10654-021-00783-z",
language = "English",
volume = "36",
pages = "1065–1074",
journal = "European Journal of Epidemiology",
issn = "0393-2990",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Body mass index and height in young adult men in relation to subsequent risk of mood disorder

AU - Okholm, Gunhild Tidemann

AU - Jorgensen, Terese Sara Hoj

AU - Rozing, Maarten Pieter

AU - Wium-Andersen, Marie Kim

AU - Wium-Andersen, Ida Kim

AU - Jorgensen, Martin Balslev

AU - Sørensen, Thorkild I. A.

AU - Osler, Merete

PY - 2021

Y1 - 2021

N2 - Adolescence represents an important period in brain and mental development, which raises the question of whether measures of body size at entry into adult life influence the risk of developing mood disorders. We examined the association of BMI and height in a cohort of young men with risk of mood disorders throughout life. The study included 630,807 Danish men born 1939-1959 and 1983-1997 with measures of height and weight at conscription board examinations. Psychiatrist's diagnosis of mood disorders was obtained from national patient registries from 1969 to 2016. The associations of BMI and height with mood disorders were estimated by Cox proportional hazard regression analyses adjusting for education, cognitive ability, migration status drug and alcohol misuse. During a mean follow-up of 26.3 years, 2,608 (0.6%) and 19,690 (3.1%) men were diagnosed with bipolar disorder and depression, respectively. We found an inverse linear association of BMI with risk of bipolar disorder, whereas the association of BMI with depression was curve-linear with a decline in risk until BMI around 25 kg/m(2), and an almost constant risk across the BMI range above 25 kg/m(2). Height was not associated with bipolar disorder or depression. Comparison of brothers, assumed to share family factors of possible influence on the risk of mood disorders, showed similar results although with wider confidence intervals. BMI in the lower range at men's entry into adulthood is inversely associated with risk of bipolar disorder and depression throughout adult life, whereas height is not related.

AB - Adolescence represents an important period in brain and mental development, which raises the question of whether measures of body size at entry into adult life influence the risk of developing mood disorders. We examined the association of BMI and height in a cohort of young men with risk of mood disorders throughout life. The study included 630,807 Danish men born 1939-1959 and 1983-1997 with measures of height and weight at conscription board examinations. Psychiatrist's diagnosis of mood disorders was obtained from national patient registries from 1969 to 2016. The associations of BMI and height with mood disorders were estimated by Cox proportional hazard regression analyses adjusting for education, cognitive ability, migration status drug and alcohol misuse. During a mean follow-up of 26.3 years, 2,608 (0.6%) and 19,690 (3.1%) men were diagnosed with bipolar disorder and depression, respectively. We found an inverse linear association of BMI with risk of bipolar disorder, whereas the association of BMI with depression was curve-linear with a decline in risk until BMI around 25 kg/m(2), and an almost constant risk across the BMI range above 25 kg/m(2). Height was not associated with bipolar disorder or depression. Comparison of brothers, assumed to share family factors of possible influence on the risk of mood disorders, showed similar results although with wider confidence intervals. BMI in the lower range at men's entry into adulthood is inversely associated with risk of bipolar disorder and depression throughout adult life, whereas height is not related.

KW - Body mass index

KW - Height

KW - Depression

KW - Bipolar disorder

KW - Cohort study

KW - DEPRESSIVE SYMPTOMS

KW - ASSOCIATION

KW - OBESITY

KW - COHORT

KW - SUICIDE

KW - OVERWEIGHT

KW - ANXIETY

KW - HEALTH

KW - TWIN

U2 - 10.1007/s10654-021-00783-z

DO - 10.1007/s10654-021-00783-z

M3 - Journal article

C2 - 34247338

VL - 36

SP - 1065

EP - 1074

JO - European Journal of Epidemiology

JF - European Journal of Epidemiology

SN - 0393-2990

ER -

ID: 274331656